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16 Possible Causes for Hyperintensities in the Globus Pallidus (T2-Weighted), Pyramidal Tract Signs, Slow Speech

Did you mean: Hyperintensities in the Globus Pallidus (T2-Weighted, Pyramidal Tract Signs, Slow Speech

  • Hallervorden-Spatz Syndrome

    Table-1: Diagnostic features of Hallervorden spatz disease [11] Obligate Features Collaborate Features Exclusion Features Onset during first two decades Pyramidal tract signs[medresearch.in] These abnormalities progressed over the years with slowing of voluntary movements, rigidity of limbs and dystonic posturing. Speech was slurred.[jpgmonline.com] This virtually pathognomonic radiographic abnormality, called the eye-of-the-tiger sign, comprises hyperintensities within a hypointense medial globus pallidus on T2-weighted[ncbi.nlm.nih.gov]

  • Binswanger Disease

    Other prominent features of the disease include urinary incontinence, difficulty walking, clumsiness, slowness of conduct, lack of facial expression, and speech difficulty[prep4usmle.com] The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[plaza.umin.ac.jp] Frequent pauses in your speech while searching for words Slow speech Difficulty repeating phrases or sentences Progressive Nonfluent-agrammatic Aphasia (PNFA) Difficulty[alzheimersweekly.com]

  • Central Pontine Myelinolysis

    In (CPM), the initial signs include dysarthria and dysphagia (secondary to corticobulbar fiber involvement), and flaccid quadriparesis (from pyramidal tract involvement) which[omicsonline.org] As a result, you may suffer from: muscle weakness in the face, arms, and legs delayed or poor reflexes and responses slowed speech and poor enunciation tremors swallowing[healthline.com] […] of Globus Pallidus (broad arrow), suggestive of Extrapontine myelinolysis.[ipfs.io]

  • Wilson Disease

    In Wilson disease, an abnormal striatum depicted on MR images correlated with pseudoparkinsonian signs, an abnormal dentatothalamic tract correlated with cerebellar signs,[pubs.rsna.org] Neurologic – the patient may present with slurred or slowed speech, tremors, dystonia, and dysphagia. Motor strength is not affected, nor are there sensory defects.[journalofethics.ama-assn.org] On T1W images, these lesions are normal to hypointense but hyperintense lesions especially in globus pallidus may also be seen [ 2 ].[omcr.oxfordjournals.org]

  • Creutzfeldt Jakob Disease

    Other neurologic findings may include cerebellar signs, pyramidal tract signs, extrapyramidal signs, corticla visual defects, abnormal extraocular movements, lower motor neuron[library.med.utah.edu] A 59-year-old woman presented with a 2-month history of headache, difficulty in finding words, and slow speech.[doi.org] Extrapontine myelinolysis manifests predominantly as areas of bilateral FLAIR /T2-weighted imaging hyperintensity in the globus pallidus, putamen, and thalamus, which are[doi.org]

  • Neurodegeneration with Brain Iron Accumulation

    . • Begins in childhood • Profound dystonia, dysarthria, spasticity and pyramidal tract signs • Pigmentary retinopathy, leading to night blindness and visual field constriction[slideshare.net] […] trunk), dysarthria (slurred or slow speech) choreoathetosis (involuntary, purposeless jerky muscle movements), muscle rigidity (uncontrolled tightness of the muscles), spasticity[ninds.nih.gov] Even before the globus pallidus hypointensity developed, patients with mutations could be distinguished by the presence of isolated globus pallidus hyperintensity on T2-weighted[ncbi.nlm.nih.gov]

  • Alexander Disease

    We report a case of genetically confirmed adult-onset AD with palatal myoclonus, pyramidal tract signs, cerebellar signs, and marked atrophy of the medulla oblongata and spinal[ncbi.nlm.nih.gov] In some cases, a bone marrow transplant can help by slowing or stopping the progression of the disease.[webmd.com] In addition, there are symmetrical hyperintensity signals in the posterior part of the globus pallidus on T2-weighted images in the two symptomatic patients, which are rarely[ncbi.nlm.nih.gov]

  • Neuroferritinopathy

    tract signs, and psychiatric symptoms.[ncbi.nlm.nih.gov] […] movements) Increased tendon reflexes Speech problems Dysarthria Difficulty using or controlling the muscles of the mouth, tongue, larynx or vocal cords, which are used to[nbiacure.org] pallidus, on T2-weighted images.[emedicine.medscape.com]

  • McLeod Neuroacanthocytosis Syndrome

    Rarely, pyramidal tract signs; and d. Rarely, cranial nerve involvement [ Kane & Havel 1995, Tarugi & Averna 2011 ]. 3.[ncbi.nlm.nih.gov] […] the expression of Kx red blood cell antigen) Symptoms of Huntington’s disease-like 2 Symptoms include: dystonia chorea exaggerated reflexes (known as hyperreflexia) very slow[medic8.com] […] pattern of hyperintensity within the hypointense medial globus pallidus.[scienceopen.com]

  • Mitochondrial Membrane Protein-Associated Neurodegeneration

    tract signs with heavy iron accumulation at the globus pallidum and the substantia nigra [ 1, 2 ].[omicsonline.org] […] surgeons, and neurosurgeons is essential.PrognosisThe progression of MPAN is usually slow and may lead to loss of independent ambulation due to spasticity, dystonia, and[malacards.org] Key Diagnostic Features: Once the parkinsonian symptoms appear, brain MRI shows hypointensity in the region of substantia nigra (SN) and globus pallidus (GP) on T2-weighted[ajnr.org]