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25 Possible Causes for Hyperintensities in the Globus Pallidus (T2-Weighted), Slow Speech

Did you mean: Hyperintensities in the Globus Pallidus (T2-Weighted, Slow Speech

  • Hallervorden-Spatz Syndrome

    These abnormalities progressed over the years with slowing of voluntary movements, rigidity of limbs and dystonic posturing. Speech was slurred.[jpgmonline.com] This virtually pathognomonic radiographic abnormality, called the eye-of-the-tiger sign, comprises hyperintensities within a hypointense medial globus pallidus on T2-weighted[ncbi.nlm.nih.gov] Intermediate forms manifest onset in first decade with slow progression or onset in second decade with rapid progression.[genecards.org]

  • Binswanger Disease

    Other prominent features of the disease include urinary incontinence, difficulty walking, clumsiness, slowness of conduct, lack of facial expression, and speech difficulty[prep4usmle.com] The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[plaza.umin.ac.jp] Frequent pauses in your speech while searching for words Slow speech Difficulty repeating phrases or sentences Progressive Nonfluent-agrammatic Aphasia (PNFA) Difficulty[alzheimersweekly.com]

  • Central Pontine Myelinolysis

    As a result, you may suffer from: muscle weakness in the face, arms, and legs delayed or poor reflexes and responses slowed speech and poor enunciation tremors swallowing[healthline.com] […] of Globus Pallidus (broad arrow), suggestive of Extrapontine myelinolysis.[ipfs.io] Clinical findings Weakness, double vision, muscle spasms, speech defects, delirium, sleep disorders, hallucinations, tremors and uncontrolled eye movements.[medical-dictionary.thefreedictionary.com]

  • Wilson Disease

    Neurologic – the patient may present with slurred or slowed speech, tremors, dystonia, and dysphagia. Motor strength is not affected, nor are there sensory defects.[journalofethics.ama-assn.org] On T1W images, these lesions are normal to hypointense but hyperintense lesions especially in globus pallidus may also be seen [ 2 ].[omcr.oxfordjournals.org] […] movements Slurred or slow speech, excessive saliva, decreased or slow facial expressions (mask-like facies) Emotional or behavioural changes Confusion, delirium or dementia[dermnetnz.org]

  • Creutzfeldt Jakob Disease

    A 59-year-old woman presented with a 2-month history of headache, difficulty in finding words, and slow speech.[doi.org] Extrapontine myelinolysis manifests predominantly as areas of bilateral FLAIR /T2-weighted imaging hyperintensity in the globus pallidus, putamen, and thalamus, which are[doi.org] Within weeks the person may complain of clumsiness and feeling muddled, become unsteady walking, and have slow or slurred speech.[alzheimers.org.uk]

  • Neurodegeneration with Brain Iron Accumulation

    […] trunk), dysarthria (slurred or slow speech) choreoathetosis (involuntary, purposeless jerky muscle movements), muscle rigidity (uncontrolled tightness of the muscles), spasticity[ninds.nih.gov] Even before the globus pallidus hypointensity developed, patients with mutations could be distinguished by the presence of isolated globus pallidus hyperintensity on T2-weighted[ncbi.nlm.nih.gov] Others may present with speech delay and autistic features, which may remain as the only evidence of disease for a year or more, given the slow progression of atypical NAD[ncbi.nlm.nih.gov]

  • Wernicke Encephalopathy

    Patients present with a slow onset of nonspecific symptoms such as headache, vertigo, movement disorders, syncope, and seizures.[doi.org] […] in the globus pallidus.[ncbi.nlm.nih.gov] Other neurologic deficits include paresis, spasticity, gait disturbance, speech disorders, coma, dementia, Parkinsonism, chorea, tremors, dystonia, myoclonia, and orthostatic[doi.org]

  • Alexander Disease

    In some cases, a bone marrow transplant can help by slowing or stopping the progression of the disease.[webmd.com] In addition, there are symmetrical hyperintensity signals in the posterior part of the globus pallidus on T2-weighted images in the two symptomatic patients, which are rarely[ncbi.nlm.nih.gov] Treating it depends on the type, and doctors address the symptoms of the disease with medications and special kinds of physical, occupational, and speech therapy .[webmd.com]

  • McLeod Neuroacanthocytosis Syndrome

    […] the expression of Kx red blood cell antigen) Symptoms of Huntington’s disease-like 2 Symptoms include: dystonia chorea exaggerated reflexes (known as hyperreflexia) very slow[medic8.com] […] pattern of hyperintensity within the hypointense medial globus pallidus.[scienceopen.com] , tremors and low speech.[rarediseases.org]

  • Neurofibromatosis Type 1

    His speech was slow but fluent and sometimes disjointed.[cureus.com] Rarely, hyperintensities and mild mass effect have been reported in the globus pallidus on T1-weighted images.[emedicine.com] If the T2 lesions show enhancement, glioma development should be suspected.[emedicine.com]

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