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12 Possible Causes for Hyperintensities in the Globus Pallidus (T2-Weighted), Stupor

Did you mean: Hyperintensities in the Globus Pallidus (T2-Weighted, Stupor

  • Wernicke Encephalopathy

    In untreated patients, stupor may progress to coma, then to death. There are no specific diagnostic studies.[] […] in the globus pallidus.[] The most common presenting symptoms of WE are mental status changes. [5] Stupor and coma are rare manifestations of WE.[]

  • Central Pontine Myelinolysis

    Large lesions cause spastic bulbar paralysis, quadriplegia, stupor or coma, or the locked-in syndrome, developing in a background of severe electrolyte abnormalities.[] […] of Globus Pallidus (broad arrow), suggestive of Extrapontine myelinolysis.[] Clinical manifestations of CPM include stupor and spastic tetraparesis[ 51 ].[]

  • Creutzfeldt Jakob Disease

    Polioencefalopatia degenerativa subacura del presenio con stupore acinetico e rigidit: decorticata con mioclonie (Varier; “rnioclonica” della malattia di Jakob Creutzfeldt[] Extrapontine myelinolysis manifests predominantly as areas of bilateral FLAIR /T2-weighted imaging hyperintensity in the globus pallidus, putamen, and thalamus, which are[] Polioencefalopatia degenerativa subacuta del presenio con stupore acinetico e rigidita decorticata con mioclonie (Varieta ‘mioclonica’ della malattia di Jakob-Creutzfeldt)[]

  • Hallervorden-Spatz Syndrome

    Other symptoms of HSD include: rigid muscles writhing movements tremors a lack of balance when walking, or ataxia seizures confusion disorientation stupor dementia weakness[] This virtually pathognomonic radiographic abnormality, called the eye-of-the-tiger sign, comprises hyperintensities within a hypointense medial globus pallidus on T2-weighted[] […] pattern of hyperintensity within the hypointense medial globus pallidus.[]

  • Neurodegeneration with Brain Iron Accumulation

    […] uncontrolled tightness of the muscles), spasticity (sudden, involuntary muscle spasms), and/or ataxia (inability to coordinate movements), confusion, disorientation, seizures, stupor[] Even before the globus pallidus hypointensity developed, patients with mutations could be distinguished by the presence of isolated globus pallidus hyperintensity on T2-weighted[] Symptoms include involuntary muscle contractions, rigidity and spasms in the limbs, face and torso, as well as confusion, disorientation, seizures, stupor and dementia.[]

  • Kernicterus

    […] tone (hypotonia) Middle stage: High-pitched cry Irritability May have arched back with neck hyperextended backwards, high muscle tone (hypertonia) Poor feeding Late stage: Stupor[] In the appropriate clinical context, bilateral globus pallidus T2-weighted and FLAIR signal hyperintensity is supportive of a diagnosis of kernicterus in an infant.[] A limited investigation of diffusion-weighted imaging (DWI) showed no distinctive signal pattern, but a larger study is required.[]

  • Binswanger Disease

    In severe cases of anoxia the patient may be in a stupor or a coma for periods ranging from hours to days, weeks, or months.[] The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[] ., tentorial and foramen magnum herniation; see Chapter 17 on stupor and coma).[]

  • Encephalopathy

    Stupor and "twitching" Case #5 A 56-year-old man who was previously well was admitted to the hospital in a stupor with clonic twitching of his left extremities and face.[] Conventional MRI may reveal hyperintense signal on T1-weighted images in the globus pallidus, subthalamic region, and midbrain, and may also show diffuse cortical edema and[] The features of HE depend on the aetiology and precipitating factors, eventually developing into stupor and then coma. some aetiologies of the hepatic failure, for example[]

  • Wilson Disease

    In the third stage, the patient is stuporous and barely responsive. In the fourth stage, the patient sinks into deep coma.[] On T1W images, these lesions are normal to hypointense but hyperintense lesions especially in globus pallidus may also be seen [ 2 ].[] The lesions showed no signal-intensity abnormality on T2-weighted images. The cause of hyperintensity in T1-weighted images remains elusive.[]

  • Cyanide Poisoning

    Neurotoxicity occurs at modest doses; initially there is CNS stimulation (dizziness, confusion, restlessness, and anxiety) which is followed by stupor, opisthotonus, convulsions[] […] recovery images in the region of the striatum and the globus pallidus.[] Thiocyanate toxicity is characterized by weakness, muscle spasm, nausea, disorientation, psychosis, hyper-reflexia, and stupor (Smith, 1973; Michenfelder & Tinker, 1977).[]

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