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26 Possible Causes for Hyperintensities in the Globus Pallidus (T2-Weighted), Sudden Death

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  • Wernicke Encephalopathy

    Patients may also suffer postural hypotension, syncope, and sudden death, probably due to involvement of brainstem cardiorespiratory centers.[] […] in the globus pallidus.[] Sudden unexpected death and Wernicke's encephalopathy, a complication of prolonged intravenous feeding. Aust N Z J Med 1980, 10:230-235. [ Links ] 9. Harper C.[]

  • Mercury Poisoning

    Sensitivity reactions to these diuretics may cause asthma, hives, other skin lesions, and sudden death.[] The T2-weighted MRI images of the patient's brain initially showed multiple hyperintense lesions in cerebral white matter, left globus pallidus, and putamen, which also improved[] §Rates of sudden death, not CHD death. Figure 2.[]

  • Kernicterus

    In the appropriate clinical context, bilateral globus pallidus T2-weighted and FLAIR signal hyperintensity is supportive of a diagnosis of kernicterus in an infant.[] A limited investigation of diffusion-weighted imaging (DWI) showed no distinctive signal pattern, but a larger study is required.[]

  • Hallervorden-Spatz Syndrome

    That year a euthanasia centre had been established at the Brandenburg-Görden centre, where there was a sudden surge in institutional deaths.[] This virtually pathognomonic radiographic abnormality, called the eye-of-the-tiger sign, comprises hyperintensities within a hypointense medial globus pallidus on T2-weighted[] […] unexplained nocturnal death syndrome, Idiopathic ventricular fibrillation, Pokkuri (Japanese), Bangungut, Lai Tai (Phillipines and Southeastern Asia) CADASIL ( 2 Files )[]

  • McLeod Neuroacanthocytosis Syndrome

    Other research is aimed at identifying possible causes of sudden death related to heart muscle abnormalities, which are observed in some individuals with neuroacanthocytosis[] […] pattern of hyperintensity within the hypointense medial globus pallidus.[] Sudden, apparently unexplained death seems to occur quite frequently in ChAc.[]

  • Neurofibromatosis Type 1

    Pheochromocytoma and myocarditis should be considered when sudden death occurs in the setting of neurofibromatosis type 1.[] Rarely, hyperintensities and mild mass effect have been reported in the globus pallidus on T1-weighted images.[] KEYWORDS: Forensic pathology; Internal carotid artery; Neurofibromatosis type 1; Sudden death; Vasculopathy[]

  • Binswanger Disease

    […] paroxysmal hemicrania , hemicrania continua , cough headache , and hypnic headache , among others infantile spasms form of cryptogenic generalized epilepsy characterized by sudden[] The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[] , forceful forward flexion of the trunk and extension of the arms infarction permanent tissue damage and death of all cellular elements ( neurons , glia, vessels) due to prolonged[]

  • 2-Hydroxyglutaric Aciduria

    Inherited metabolic disorders are the cause of a small but significant number of sudden unexpected deaths in infancy.[] In 43 patients (77%) the globus pallidus was more hyperintense on the T2-weighted MR images than the caudate nucleus and putamen ( , Fig 5 ).[] Sudden death has not been reported in association with L-2-hydroxyglutaric aciduria so far, but since this inborn error of metabolism is potentially treatable, early diagnosis[]

  • Alpers Syndrome

    Eur J Pediatr 2011; 170 : 1481 51) Yen T-Y, Hwu W-L, Chien Y-H, et al: Acute metabolic decompensation and sudden death in Barth syndrome: report of a family and a literature[] The right parietal cortex appears normal in the T2-weighted images.[] […] hepatic failure, and death occurs within a short time.[]

  • Autosomal Dominant Progressive External Ophthalmoplegia Type 6

    death Endocrine – diabetes, thyroid disease, parathyroid disease Gastrointestinal – constipation, irritable bowel syndrome, dysphagia, anorexia, abdominal pain, diarrhea[] T2-weighted axial MR image demonstrates bilateral hyperintense signal abnormalities in the globus pallidus (arrows).[] BSS is associated with a poor outcome as patients present an elevated risk for sudden death in their first year of life.[]

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