(C) Hyperkeratosis and marked epithelial hyperplasia with microabcesses; superficial perivascular and diffuse infiltrate (HE;×10).
Verrucous - Skin lesions are in the form of warts and hyperkeratosis.
Microscopically the skin shows hyperkeratosis and pseudoepitheliomatous hyperplasia and a diffuse chronic inflammatory infiltrate.
Skin changes are common and include hyperkeratosis, hyperpigmentation, verrucae, papillomas, and fungal infections.
[…] of scrotum Lymphedema of uncertain etiology Lymphedema of vulva Lymphedema praecox Lymphedema, after surgery Lymphedema, limb Lymphedema, lower extremity Lymphedematous hyperkeratosis
Elephantiasis (extreme hyperkeratosis of skin in a limb affected by lymphedema) is a severe manifestation of lymphedema.
People with triple A syndrome frequently develop a thickening of the outer layer of skin (hyperkeratosis) on the palms of their hands and the soles of their feet.
Syndrome hydrolethalus syndrome + Hydroxylysinuria hypereosinophilic syndrome + hyperferritinemia-cataract syndrome Hyperimmunoglobulin G1(A1) Syndrome hyperinsulinism + Hyperkeratosis-Hyperpigmentation
Scattered follicular hyperkeratosis appears on the trunk.
[…] literature have the following features in common: (1) a distinctive ichthyosis characterized by a fine dry scale, follicular hyperkeratotic spines, and a reticulated pattern of hyperkeratosis
Low-dose acitretin (10-25mg daily) or isotretinoin (20mg daily) may be needed to improve hyperkeratosis and follicular occlusion.
Moreover, insulin resistance and the appearance of acanthosis nigricans, a papillomatous pigmented hyperkeratosis of the skin appearing on the flexures of the neck in most
Acanthosis nigricans (AN) is a velvety and papillomatous pigmented hyperkeratosis of the skin, which has been recognized in some genetic disorders more severe than HCH involving
AN is a velvety and papillomatous pigmented hyperkeratosis of the skin, which appears mainly on the flexures and neck.
[…] cells Can be an advanced form of mycosis fungoides or arise de novo Characteristic triad of symptoms Systemic skin lesions Erythroderma accompanied by palmar and plantar hyperkeratosis
Case 1 A male patient, aged 30 years, was admitted to our Department with extremely itchy erythroderma with generalized peripheral lymphadenopathy and hyperkeratosis of the
Ichthyosiform MF has similar histopathologic findings to classic MF combined with features of ichthyosis, such as hypogranulosis and hyperkeratosis.25 The detection of features
Approximately 1 month after thallium exposure, Mees lines (transverse white lines on the nails) appear in the nail plate.  Other dermatologic findings include well-demarcated hyperkeratosis
Skin and nail symptoms include hardened patches of skin (hyperkeratosis) with unusually deep creases on the palms of the hands and the soles of the feet, unusual darkening
Skin hyperkeratosis and pigmentation and arthritis are also relatively uncommon.
Ichthyosis is a generalized skin disease characterized by hyperkeratosis, in which the skin acquires an appearance resembling fish scales.
General edema and hyperkeratosis were seen in both extremities and trunk. Figure 1.
Associated features include severe pruritus, palmoplantar hyperkeratosis, lichenification, edema, and exfoliation. The etiology remains largely unknown.
A biopsy was performed, and histologic analysis revealed acanthosis and papillomatosis, hyperkeratosis, increased dermal pigmentation, and a dermal lymphohistiocytic infiltrate
Abstract Acanthosis nigricans is a mucocutaneous dermatosis characterized by hyperpigmentation and a velvety papillomatous hyperkeratosis.
This is a descriptive term for a velvety or verrucous brown-to-black area of hyperkeratosis.
The face is generally spared; however, hyperkeratosis of the palms and soles and follicular hyperkeratosis of the cheek and neck is often present. Pruritus is frequent.
Hence, this type of hyperkeratosis can be distinguished from other types of inherited palmoplantar keratosis.
As the child grows, the bullous lesions subside, but he/she develops more hyperkeratosis.
If less than 2 mm of hyperkeratosis is present, no points are awarded.
The infection was characterized clinically by yellow-brown discoloration of the nail plate, distal-lateral onycholysis and subungual hyperkeratosis of the first left toenail
Nail plate and subungual horn with hyperkeratosis. There are faint hyphae coursing through the keratin, even at high power.
Histopathology of leukoplakia can disclose hyperkeratosis with dysplasia or carcinoma or hyperkeratosis or parakeratosis without dysplasia.
PVL generally presents as a simple benign form of hyperkeratosis that tends to spread and become diffuse.
What is Hyperkeratosis? Hyperkeratosis is a layered buildup of keratinized cell tissue and is distinctive for its leaf-like appearance.
Keratin cysts [Figure 4], are present consistent with SK Penile lesion: Section shows papillomatosis with hyperkeratosis and acanthosis.
Histologic findings revealed massive epidermal hyperplasia, hyperkeratosis, parakeratosis, and viral cytopathic effects, features that are consistent with condyloma.
Further characteristics of BLT are hyperkeratosis, parakeratosis, papillomatosis, acanthosis, and koilocytosis. The tumor may show infiltration by lymphocytes.
There was hyperkeratosis with foci of mounds of parakeratosis. Spongiosis with neutrophilic infiltration and microabscess formation were prominent.
Examination revealed distal onycholysis of the fingernails, as well as onycholysis and subungual hyperkeratosis of the toenails.
Subungual hyperkeratosis results in lifting up of the nail plate from the nail bed causing deformity resembling onycholysis.
[…] deficit, spasticity in the lower limbs (spastic paraplegia), pes cavus deformity of both feet, an abnormal gait, and palmar and plantar hyperkeratosis.
[…] is hyperkeratosis of the sole of the foot.
Some types of hyperkeratosis are inherited conditions. They may be present at birth. Other kinds of hyperkeratosis may be early signs of skin cancer.
Abstract Characteristics of alcoholic neuropathy have been obscured by difficulty in isolating them from features of thiamine-deficiency neuropathy. We assessed 64 patients with alcoholic neuropathy including subgroups without (ALN) and with (ALN-TD) coexisting thiamine deficiency. Thirty-two patients with[…]
The patient's skin disease was more remarkable for its hyperpigmentation than its hyperkeratosis.
Squames / scales Pathophysiology genetic disorders / keratinocyte genetic disorders / palmoplantar keratoderma Symptoms Burning, Diagnosis hyperkeratosis palmaris et plantaris
Histology of plantar skin revealed compact hyperkeratosis and irregular epidermal hyperplasia. Mycosis was excluded histologically.
Microscopic Features:  Hyperkeratosis (more keratin - thick stratum corneum) - in "columns"; keratin in separate towers - not a flat thick sheet.
(Med J Indones 2008; 18: 135-8) Key words: papilloma viruses, hyperkeratosis, orthokeratosis Copyright (c) 2009 Mona S. Haroen, Herliyani M.
LM papillomatous hyperplasia (rete ridges long & curve inward), hyperkeratosis, hypergranulosis, large blood vessels at the dermal-epidermal junction, +/-viral changes - perinuclear
The histologic findings include papillomatosis, hyperkeratosis, and minimal or no acanthosis.
Histopathologically, hyperkeratosis, decreased granular layer, irregular papillomatosis, and hypermelanosis of the basal layer were present.
Key histological features of Confluent and reticulated papillomatosis (i) undulating basket-weave hyperkeratosis, (ii) papillomatosis, (iii) focal acanthosis limited to the
Criteria evaluated included hyperkeratosis, epidermal atrophy, follicular plugging, basal cell vacuolation, vascular ectasia, hyalinosis, inflammatory infiltrate, dermal edema
A punch biopsy from an atrophic plaque was performed, and it revealed hyperkeratosis, atrophic epidermis, basal layer vacuolar degeneration, mild lymphocytic infiltration
Hyperkeratosis, epidermal atrophy, a swollen dermal collagen bundle, and prominent edema was evident (B) (H&E, original magnification ×200).
Histopathology mostly showed hyperkeratosis, acanthosis, prominent granular layer, spongiosis and dermal infiltrate.
A lesional biopsy revealed hyperkeratosis, psoriasiform acanthosis, spongiosis, normal granular layer and minimal perivascular mononuclear infiltrate [Figure 3].
[…] well-demarcated scaling erythematous papules and plaques with secondary lichenification and later hyperpigmentation. 3 Histologically, NAE is characterized by acanthosis, hyperkeratosis
The histologic appearance is similar to oral leukoplakia, with hyperkeratosis and acanthosis.
Histologically, hyperkeratosis, acanthosis, and subepithelial and perivascular infiltrate of round cells may be seen. Dyskeratosis may be present.
We present a case of focal acral hyperkeratosis in a 9‐year‐old girl.
Kim, Focal acral hyperkeratosis, Clinical and Experimental Dermatology, 32, 5, (608), (2007). E.
The clinicopathologic distinction between focal acral hyperkeratosis and acrokeratoelastoidosis is blurred.
On examination, diffuse hyperkeratosis of the palms and soles was observed (Figure 1 a, b) However, there was no extension of this hyperkeratosis to the dorsal aspects of
These findings suggested an association between internal malignancy and palmoplantar hyperkeratosis.
Fig. 2 Hyperkeratosis sparing the arches of feet.
Patients may also present with malodorous hyperhidrosis, follicular hyperkeratosis, nail dystrophy or dural calcifications.
Pa·pil·lon-Le·fèv·re syn·drome ( pah-pē-on[h]' le-fĕv ), [MIM*245000] a congenital hyperkeratosis of the palms and soles, with progessive destruction of alveolar bone about
[…] considerable hyperkeratosis of palms and soles [ Figure 6 ].
Medical treatment includes use of emollients and topical keratolytics (urea or lactic acid based) for softening of the nail plates and palmoplantar hyperkeratosis, topical
Hidrotic ectodermal dysplasia is a rare genodermatosis with clinical hallmarks of alopecia, nail dystrophy, and palmoplantar hyperkeratosis.
Also, skin emollients, keratolytics, and other therapies may be used for the hyperkeratosis.
Histological analysis of the wart lesions showed epidermis with hyperkeratosis, regular acanthosis, hypergranulosis, and cells with abundant basophilic cytoplasm.
[…] destructive methods Clinical images Images hosted on other servers: Various images Arm Microscopic (histologic) description Classic features are mild to moderate acanthosis and hyperkeratosis
Skin biopsy shows verruca plana-like lesions with mild hyperkeratosis, hypergranulosis and acanthosis of the epidermis.
[…] or parakeratosis Nuclear atypia not seen Microscopic (histologic) images Images hosted on other servers : Mild hyperkeratosis Epithelial thickening Chronic inflammatory cell
Eczematous inflammation or hyperkeratosis may be present. Prevalence: Common, 40% to 45% of non-neoplastic epithelial disorders.
Fifteen patients had lichen sclerosus with various degrees of hyperkeratosis, while one had human papillomavirus-associated vulvar intraepithelial neoplasia and another had
However, the main histological features of kraurosis vulvae are nonspecific (luminal hyperkeratosis, acanthosis, infiltration of lymphocytes, thickening of the basement membrane
Convert to ICD-10-CM : 624.09 converts approximately to: 2015/16 ICD-10-CM N90.4 Leukoplakia of vulva Approximate Synonyms Dystrophy of vulva Hyperkeratosis of vulva Leukoplakia
Asymptomatic patients Treatment is recommended if patients have features of active disease - eg, ecchymosis, hyperkeratosis or progressive atrophy.