Hyperkeratosis Causes & Reasons

Neu Starten

Ad Html Headline Ad Text Headline

Ad Label Ad Html Description Ad Text Description

Determine your risk of now. Restart test

Caution! In case of an emergency:

Seek emergency care

Caution! In case of an emergency: Seek emergency care

Hi, I'm Symptoma.

Hyperkeratosis Symptom Checker: Possible causes include Acanthosis Nigricans. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

For full functionality of this site it is necessary to enable JavaScript.

How to enable JavaScript?

Possible Causes

Acanthosis Nigricans

A biopsy was performed, and histologic analysis revealed acanthosis and papillomatosis, hyperkeratosis, increased dermal pigmentation, and a dermal lymphohistiocytic infiltrate [doi.org]

Abstract Acanthosis nigricans is a mucocutaneous dermatosis characterized by hyperpigmentation and a velvety papillomatous hyperkeratosis. [ncbi.nlm.nih.gov]

Acanthosis nigricans (AN) is a skin disorder characterized by focal or diffuse hyperkeratosis symmetric hyperpigmentation of the skin and oral cavity mucosa. [ncbi.nlm.nih.gov]

Show info

Lymphedema

[…] of scrotum Lymphedema of uncertain etiology Lymphedema of vulva Lymphedema praecox Lymphedema, after surgery Lymphedema, limb Lymphedema, lower extremity Lymphedematous hyperkeratosis [icd9data.com]

Hyperkeratosis and papillomas may also be seen in someone with lymphedema. Hyperkeratosis is an overgrowth of the skin like a very thick callus. [oncolink.org]

Stage III lymphedema is characterized by a tremendous increase in volume, hardening of the dermal tissues, hyperkeratosis, and papillomas of the skin. [nortonschool.com]

Show info

Ichthyosis Vulgaris

Abstract To elucidate the pathogenesis of impaired barrier function and the influence of surfactant on the stratum corneum in hyperkeratosis, we investigated morphological [ncbi.nlm.nih.gov]

Hence, this type of hyperkeratosis can be distinguished from other types of inherited palmoplantar keratosis. [ncbi.nlm.nih.gov]

Abstract Ichthyosis vulgaris is an autosomal dominant disorder of keratinization characterized by mild hyperkeratosis and reduced or absent keratohyalin granules in the epidermis [ncbi.nlm.nih.gov]

Show info

Carcinoid Tumor

Skin hyperkeratosis and pigmentation and arthritis are also relatively uncommon. [emedicine.medscape.com]

Show info

Actinic Keratosis

The features in favour of AK were parakeratosis, hyperkeratosis, more severe keratinocyte pleomorphism and architectural disruption, and the presence of epidermal inflammatory [ncbi.nlm.nih.gov]

Validation of the AK-FAS showed good reproducibility for AK area and hyperkeratosis, even for dermatologists untrained on use of the scale. [ncbi.nlm.nih.gov]

Hyperkeratosis represents the most important limitation in the evaluation of squamous neoplasia as it may impair the analysis of deeper epidermal and dermal structures significantly [ncbi.nlm.nih.gov]

Show info

Cutaneous T-Cell Lymphoma

[…] cells Can be an advanced form of mycosis fungoides or arise de novo Characteristic triad of symptoms Systemic skin lesions Erythroderma accompanied by palmar and plantar hyperkeratosis [amboss.com]

Case 1 A male patient, aged 30 years, was admitted to our Department with extremely itchy erythroderma with generalized peripheral lymphadenopathy and hyperkeratosis of the [cyberleninka.org]

Ichthyosiform MF has similar histopathologic findings to classic MF combined with features of ichthyosis, such as hypogranulosis and hyperkeratosis.25 The detection of features [actasdermo.org]

Show info

Onychomycosis

The infection was characterised clinically by yellowish pigmentation of the nail plate and mild nail bed hyperkeratosis of the first left toe. [ncbi.nlm.nih.gov]

The infection was characterized clinically by yellow-brown discoloration of the nail plate, distal-lateral onycholysis and subungual hyperkeratosis of the first left toenail [ncbi.nlm.nih.gov]

If less than 2 mm of hyperkeratosis is present, no points are awarded. [jamanetwork.com]

Show info

Alcoholic Neuropathy

Abstract Characteristics of alcoholic neuropathy have been obscured by difficulty in isolating them from features of thiamine-deficiency neuropathy. We assessed 64 patients with alcoholic neuropathy including subgroups without (ALN) and with (ALN-TD) coexisting thiamine deficiency. Thirty-two patients with[…] [ncbi.nlm.nih.gov]

Show info

Fitzsimmons-McLachlan-Gilbert Syndrome

[…] is hyperkeratosis of the sole of the foot. [en.wikipedia.org]

Some types of hyperkeratosis are inherited conditions. They may be present at birth. Other kinds of hyperkeratosis may be early signs of skin cancer. [healthline.com]

[…] often, hyperkeratosis develops on skin that has not been irritated. [drugs.com]

Show info

Leukoplakia

What is Hyperkeratosis? Hyperkeratosis is a layered buildup of keratinized cell tissue and is distinctive for its leaf-like appearance. [entcolumbia.org]

Histopathology of leukoplakia can disclose hyperkeratosis with dysplasia or carcinoma or hyperkeratosis or parakeratosis without dysplasia. [ncbi.nlm.nih.gov]

PVL generally presents as a simple benign form of hyperkeratosis that tends to spread and become diffuse. [ncbi.nlm.nih.gov]

Show info

Confluent and Reticulated Papillomatosis

We observed invagination of basket-weave hyperkeratosis through the epidermis. [ncbi.nlm.nih.gov]

The histologic findings include papillomatosis, hyperkeratosis, and minimal or no acanthosis. [ncbi.nlm.nih.gov]

Histopathologically, hyperkeratosis, decreased granular layer, irregular papillomatosis, and hypermelanosis of the basal layer were present. [ncbi.nlm.nih.gov]

Show info

Palmoplantar Keratosis

0 ratings Abstract: We report a rare genetic condition characterized by gingival hyperkeratosis with skin changes affecting the hands and feet. [dental-update.co.uk]

We present a case of focal acral hyperkeratosis in a 9‐year‐old girl. [www3.interscience.wiley.com]

Clinical relevance: To inform clinicians of both the intra-oral and extra-oral features of focal palmoplantar and gingival hyperkeratosis. [dental-update.co.uk]

Show info

Hypochondroplasia

Acanthosis nigricans (AN) is a velvety and papillomatous pigmented hyperkeratosis of the skin, which has been recognized in some genetic disorders more severe than HCH involving [ncbi.nlm.nih.gov]

Moreover, insulin resistance and the appearance of acanthosis nigricans, a papillomatous pigmented hyperkeratosis of the skin appearing on the flexures of the neck in most [symptoma.com]

AN is a velvety and papillomatous pigmented hyperkeratosis of the skin, which appears mainly on the flexures and neck. [eje.bioscientifica.com]

Show info

Papillon Lefevre Disease

Patients may also present with malodorous hyperhidrosis, follicular hyperkeratosis, nail dystrophy or dural calcifications. [rarediseases.info.nih.gov]

Keywords: Papillon-Lefèvre Syndrome, Periodontitis, Palmoplantar, Hyperkeratosis, Cathepsin C 1. [slideshare.net]

Pa·pil·lon-Le·fèv·re syn·drome ( pah-pē-on[h]' le-fĕv ), [MIM*245000] a congenital hyperkeratosis of the palms and soles, with progessive destruction of alveolar bone about [medical-dictionary.thefreedictionary.com]

Show info

Diffuse Palmoplantar Keratoderma

On examination, diffuse hyperkeratosis of the palms and soles was observed (Figure 1 a, b) However, there was no extension of this hyperkeratosis to the dorsal aspects of [ncbi.nlm.nih.gov]

These findings suggested an association between internal malignancy and palmoplantar hyperkeratosis. [ncbi.nlm.nih.gov]

Fig. 2 Hyperkeratosis sparing the arches of feet. [indianpediatrics.net]

Show info

Howell-Evans Syndrome

ESOPHAGEAL CANCER Palmoplantar Keratoderma With Esophageal Cancer TOC Keratosis palmaris et plantaris with esophageal cancer TYLOSIS WITH ESOPHAGEAL CANCER; TOC Palmoplantar hyperkeratosis-esophageal [wikidata.org]

Symptoms and Signs Some symptoms of Howel-Evans syndrome include hyperkeratosis of palms, hyperkeratosis of the soles of the feet, and esophageal cancer. [dianamossop.com]

Potential Signs and Symptoms Some symptoms of Howel-Evans syndrome consist of hyperkeratosis of palms, hyperkeratosis of the soles of the feet, and esophageal cancer. [besttreatmenthq.com]

Show info

Hidrotic Ectodermal Dysplasia

Also, skin emollients, keratolytics, and other therapies may be used for the hyperkeratosis. [symptoma.com]

Hidrotic ectodermal dysplasia is a rare genodermatosis with clinical hallmarks of alopecia, nail dystrophy, and palmoplantar hyperkeratosis. [ncbi.nlm.nih.gov]

Clouston's syndrome is an ectodermal dysplasia characterized by dystrophic nails, alopecia, and palmoplantar hyperkeratosis. [ncbi.nlm.nih.gov]

Show info

Zinc-Responsive Necrolytic Acral Erythema

This patient also had hyperkeratosis of the palms and soles and involvement of the face. [emedicine.medscape.com]

Others have noted epidermal necrosis with or without blister formation; vacuolar degeneration of the basal layer; and psoriatic changes with acanthosis, papillomatosis, hyperkeratosis [slideshare.net]

Histopathology mostly showed hyperkeratosis, acanthosis, prominent granular layer, spongiosis and dermal infiltrate. [ingentaconnect.com]

Show info

Vulvar Dystrophy

Fifteen patients had lichen sclerosus with various degrees of hyperkeratosis, while one had human papillomavirus-associated vulvar intraepithelial neoplasia and another had [ncbi.nlm.nih.gov]

[…] or parakeratosis Nuclear atypia not seen Microscopic (histologic) images Images hosted on other servers : Mild hyperkeratosis Epithelial thickening Chronic inflammatory cell [pathologyoutlines.com]

Eczematous inflammation or hyperkeratosis may be present. Prevalence: Common, 40% to 45% of non-neoplastic epithelial disorders. [clinicalgate.com]

Show info

Angiokeratoma Circumscriptum

Angiokeratomas are benign cutaneous lesions characterized by ectasia of papillary dermis vessels and secondary epidermal changes like hyperkeratosis. [symptoma.com]

The type of lesion varied from discrete macules with no or slight hyperkeratosis to confluent, protruding verrucous plaques. [ncbi.nlm.nih.gov]

Angiokeratomas are relatively rare vascular lesions characterized by ectasias of the papillary dermal blood vessels with secondary epidermal changes in the form of acanthosis and/or hyperkeratosis [ncbi.nlm.nih.gov]

Show info

Bazex Syndrome

The patient's skin disease was more remarkable for its hyperpigmentation than its hyperkeratosis. [ncbi.nlm.nih.gov]

Squames / scales Pathophysiology genetic disorders / keratinocyte genetic disorders / palmoplantar keratoderma Symptoms Burning, Diagnosis hyperkeratosis palmaris et plantaris [dermquest.com]

Histology of plantar skin revealed compact hyperkeratosis and irregular epidermal hyperplasia. Mycosis was excluded histologically. [bmccancer.biomedcentral.com]

Show info

Kraurosis Vulvae

However, the main histological features of kraurosis vulvae are nonspecific (luminal hyperkeratosis, acanthosis, infiltration of lymphocytes, thickening of the basement membrane [symptoma.com]

When kraurosis vulva there is atrophy and hyperkeratosis of stratified squamous epithelium proliferation of fibrous connective tissue, leading to distortion and reduction [medicalformat.com]

Convert to ICD-10-CM : 624.09 converts approximately to: 2015/16 ICD-10-CM N90.4 Leukoplakia of vulva Approximate Synonyms Dystrophy of vulva Hyperkeratosis of vulva Leukoplakia [icd9data.com]

Show info

Thallium Poisoning

Approximately 1 month after thallium exposure, Mees lines (transverse white lines on the nails) appear in the nail plate. [22] Other dermatologic findings include well-demarcated hyperkeratosis [emedicine.medscape.com]

Skin and nail symptoms include hardened patches of skin (hyperkeratosis) with unusually deep creases on the palms of the hands and the soles of the feet, unusual darkening [rarediseases.org]

Show info

Arsenical Keratosis

[…] is hyperkeratosis of the sole of the foot. [en.wikipedia.org]

Patient case no. 2022 Date added 18 May 2003 Patient details Age --Undetermined-- Localisation Upper limbs / hands / palms Description Primary Lesions Papule / hyperpigmented Hyperkeratosis [dermquest.com]

Oral retinoids may be helpful in reducing hyperkeratosis secondary to chronic arsenicism. [ncbi.nlm.nih.gov]

Show info

Keratosis Pilaris

Keratosis pilaris (KP) is a common inherited disorder of follicular hyperkeratosis It is characterized by small, folliculocentric keratotic papules that may have surrounding [ncbi.nlm.nih.gov]

Abstract Folliculitis spinulosa decalvans is an uncommon condition characterized by follicular hyperkeratosis, followed by scarring alopecia. [ncbi.nlm.nih.gov]

BACKGROUND: Keratosis pilaris atrophicans defines a group of cutaneous disorders characterized by follicular hyperkeratosis and scarring. [ncbi.nlm.nih.gov]

Show info

Verruca Vulgaris

Histopathologic findings from three skin regions revealed characteristic features of epidermolytic hyperkeratosis, verruca vulgaris, and disseminated superficial porokeratosis [ncbi.nlm.nih.gov]

Microscopic Features: [1] Hyperkeratosis (more keratin - thick stratum corneum) - in "columns"; keratin in separate towers - not a flat thick sheet. [librepathology.org]

LM papillomatous hyperplasia (rete ridges long & curve inward), hyperkeratosis, hypergranulosis, large blood vessels at the dermal-epidermal junction, /-viral changes - perinuclear [librepathology.org]

Show info

Lichen Sclerosus

Criteria evaluated included hyperkeratosis, epidermal atrophy, follicular plugging, basal cell vacuolation, vascular ectasia, hyalinosis, inflammatory infiltrate, dermal edema [ijdpdd.com]

A punch biopsy from an atrophic plaque was performed, and it revealed hyperkeratosis, atrophic epidermis, basal layer vacuolar degeneration, mild lymphocytic infiltration [ncbi.nlm.nih.gov]

Following an incisional biopsy and microscopy, the lesion was shown to be covered by a stratified squamous epithelium showing hyperkeratosis and atrophy. [ncbi.nlm.nih.gov]

Show info

Erythema Palmaris Hereditarium

It is aymptomatic without scaling, hyperkeratosis or hyperidrosis. [lucianoschiazza.it]

The entire family has diffuse hyperkeratosis and hyperkeratosis of all nails affecting both hands and feet symmetrically. [faoj.org]

Hyperkeratosis of the umbilicus and nipple areolae were present, as well as very mild thickening and dryness of the knees and elbows. [genome.jp]

Show info

Ovarian Cyst

[…] little or no hyperkeratosis. [orpha.net]

Histological findings of orthokeratotic hyperkeratosis and acanthosis confirm our diagnosis. [e-ijd.org]

[…] of the distal nails and focal palmoplantar hyperkeratosis. [idoj.in]

Show info

Pachyonychia Congenita

Citation: Higgins E, Capra M, Schwartz ME, Smith FJD, McLean WHI, Irvine AD, Resolution of the plantar hyperkeratosis of pachyonychia congenita during chemotherapy for Ewing [tara.tcd.ie]

A 28-year-old woman developed subungual hyperkeratosis of all toe-nails and thumb-nails associated with pain on pressure and walking. [ncbi.nlm.nih.gov]

Patients with Jadassohn-Lewandowsky Syndrome (MIM #167200; PC-1) have nail defects (onchyogryposis), palmoplantar hyperkeratosis, follicular hyperkeratosis and oral leukokeratosis [ncbi.nlm.nih.gov]

Show info

⚕ Symptoma®️ is a digital health assistant but no replacement for the opinion and judgement of medical professionals. By using this website you fully understand and accept that it shall not be used as a diagnostic system for decision-making. It absolutely must not be used to obtain, replace or overrule a clinical diagnosis by a healthcare professional. It is always for the medical professional to make the final diagnosis. The medical information provided on this website is of a general nature and can not substitute for the advice of a medical professional (for example, a qualified doctor or physician)! Information from the internet could and should NOT be solely used to offer or render a medical opinion or otherwise engage in the practice of medicine.