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175 Possible Causes for Hyperkeratotic Nails

  • Tazarotene

    Given the well-documented efficacy of tazarotene on hyperkeratotic nail psoriasis, we investigated its therapeutic use in onychomycosis.[ncbi.nlm.nih.gov]

  • Pancreatic Insufficiency

    The nails were hyperkeratotic. Morphologic findings were slight, regular acanthosis and severe diffuse hyperkeratosis with variable parakeratosis.[ncbi.nlm.nih.gov]

  • Chronic Mucocutaneous Candidiasis

    Cracked and hyperkeratotic nails with prominent discoloration are commonly seen. The periungual regions are edematous and erythematous.[symptoma.com] The image below depicts CMC of the nails. Thickened, fragmented, hyperkeratotic nails and erythematous periungual skin. Courtesy of Walter Reed Army Medical Center.[emedicine.medscape.com] Skin lesions are crusted, pustular, erythematous, and hyperkeratotic. Scalp lesions may result in scarring alopecia.[merckmanuals.com]

  • Oligoarthritis

    FIGURE 2 Hyperkeratotic nails, swollen toe The patient had subungual hyperkeratosis, onycholysis, and dactylitis of the fourth toe. What is your diagnosis?[mdedge.com] The patient’s feet had crusted plaques on the plantar surface, hyperkeratotic nails with thick subungual debris, and swelling and tenderness of the fourth toes bilaterally[mdedge.com]

  • Shwachman Syndrome

    The nails were hyperkeratotic. Morphologic findings were slight, regular acanthosis and severe diffuse hyperkeratosis with variable parakeratosis.[ncbi.nlm.nih.gov]

  • Nail Abnormality

    In DLSO, remove nail and hyperkeratotic nail bed with clippers. In SWO debride abnormal nail with a curette.[thefootshop.org.uk] Skin-coloured or hyperpigmented lesions appearing as keratotic or hyperkeratotic or warty papules and plaques found on the proximal and lateral nail folds and hyponychium.[patient.info] Treatment is with systemic antifungal agents: terbinafine, itroaconazole, fluconazole. 1 Need to debride dystrophic nails.[thefootshop.org.uk]

  • Onychomycosis

    Given the well-documented efficacy of tazarotene on hyperkeratotic nail psoriasis, we investigated its therapeutic use in onychomycosis.[dovepress.com] Nail filing and nail polish can lessen cosmetic effects. It is helpful to trim dystrophic nails. In DLSO, remove nail and hyperkeratotic nail bed with clippers.[patient.info]

  • Epidermolysis Bullosa Simplex Type Cockayne-Touraine

    […] shedding, hyperkeratotic nails and shedding, palmoplantar hyperkeratosis, clumped tonofilaments on EM, normal life span but rare ass with early death due to sepsis, anemia[flashcardbook.com] […] birth or within a few weeks of life at which time they take on characteristic clustered herpetiformis apperance, may heal with some scarring and milia oral blisters common, nail[flashcardbook.com]

  • Hoyeraal-Hreidarsson Syndrome

    Dyskeratosis congenita (DC) is a bone-marrow failure syndrome characterized by early onset of reticulate skin hyperpigmentation, nail dystrophy, hyperkeratotic palms, hypotrichosis[genedx.com]

  • Epidermolysis Bullosa Pruriginosa

    There was no toe-nail dystrophy.[ncbi.nlm.nih.gov] Histopathology report showed the lesions had hyperkeratotic, mild acanthosis, dermal lymphohistiocytic infiltrate and subepidermal cleft.[ncbi.nlm.nih.gov]

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