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974 Possible Causes for Hyperlipidemia, Splenomegaly

  • Hypertriglyceridemia

    The potential etiologies of splenomegaly vary with the patient’s age.[clinchem.aaccjnls.org] […] gene), hyperlipoproteinemia type 1D (HLPP1D: Hyperlipoproteinemia 1D) (GPIHBP1 gene), hyperlipoproteinemia IIB (APOC2 gene), hyperlipoproteinemia type V (APOA5 gene), familial[ivami.com] Hyperlipidemia (ie, elevated plasma cholesterol or triglyceride levels or both) is present in all hyperlipoproteinemias.[emedicine.medscape.com]

  • Niemann-Pick Disease Type B

    Most patients initially presented with splenomegaly (78%) or hepatomegaly (73%).[ncbi.nlm.nih.gov] , Broad- or floating-betalipoproteinemia, Combined hyperlipidemia, Elevated cholesterol with elevated triglycerides NEC, Fredrickson Type IIb or III hyperlipoproteinemia,[genedx.com] Other clinical features include: interstitial lung disease short stature with delayed skeletal maturation ocular abnormalities (cherry red maculae) hyperlipidemia (which can[radiopaedia.org]

  • Alcoholic Liver Disease

    Splenomegaly : Portal hypertension causes the spleen to enlarge (a condition called splenomegaly).[msdmanuals.com] Zieve syndrome, a rarely reported disease resulting from alcohol abuse, consists of a triad of symptoms: hemolytic anemia, cholestatic jaundice, and transient hyperlipidemia[ncbi.nlm.nih.gov] Rarely, patients with fatty liver or cirrhosis present with Zieve syndrome (hyperlipidemia, hemolytic anemia, and jaundice).[merckmanuals.com]

  • Hypersplenism

    While 38 patients displayed splenomegaly, 121 showed normal spleen volumes at 6 months after LDLT (LDLT).[ncbi.nlm.nih.gov] Lipid storage diseases are Familial hyperlipidemia like: Deficiency of alpha-lipoprotein. Poorly controlled diabetes. Hypothyroidism. Prolonged obstructive jaundice.[labpedia.net] Introduction Splenomegaly and hypersplenism can develop in association with hemolytic anemia.[nethealthbook.com]

  • Niemann-Pick Disease

    Common disease-related morbidities included splenomegaly (96.6%), hepatomegaly (91.4%), liver dysfunction (82.6%), and pulmonary disease (75.0%).[ncbi.nlm.nih.gov] , Broad- or floating-betalipoproteinemia, Combined hyperlipidemia, Elevated cholesterol with elevated triglycerides NEC, Fredrickson Type IIb or III hyperlipoproteinemia,[genedx.com] Hepatosplenomegaly, was detected at 6 weeks of age; the splenomegaly resolved following CBSCT. Recovery was complicated by graft-versus-host disease.[ncbi.nlm.nih.gov]

  • Gaucher Disease

    HALS for GD patients with refractory hypersplenism and massive splenomegaly is safe and feasible in experienced hands.[ncbi.nlm.nih.gov] […] schema:about ; # Hyperlipidemias schema:about ; # Lipodystrophy schema:bookFormat bgn:PrintBook ; schema:contributor ; # Miguel Angel Yáñez Polo schema:datePublished " 1975[worldcat.org] After 4years of ERT, therapeutic goals for thrombocytopenia and splenomegaly had been achieved in 100% of patients; goals for anemia and hepatomegaly had been achieved in[ncbi.nlm.nih.gov]

  • Nephrotic Syndrome

    We herein describe a case of nephrotic syndrome with thrombocytopenia, lymphadenopathy, systemic inflammation, splenomegaly, kidney enlargement, and progressive renal insufficiency[ncbi.nlm.nih.gov] This study included patients with hyperlipidemia (n 37), the PNS with hyperlipidemia group (n 62), PNS without hyperlipidemia group (n 33), and healthy controls (n 73).[ncbi.nlm.nih.gov] Patients present with marked oedema, proteinuria, hypoalbuminemia, and often hyperlipidemia 1 .[radiopaedia.org]

  • Portal Hypertension

    We performed LS in 83 patients with massive splenomegaly ( 30 cm) secondary to portal hypertension and liver cirrhosis.[ncbi.nlm.nih.gov] Statins are widely used to treat hyperlipidemia, which is a common condition after OLT.[ncbi.nlm.nih.gov] Laparoscopic splenectomy (LS) is relatively contraindicated in cirrhotic portal hypertension (CPH) patients with complicating hypersplenic splenomegaly (HS).[ncbi.nlm.nih.gov]

  • Pyruvate Kinase Deficiency

    Significant hyperbilirubinaemia, anemia, and splenomegaly are common features in patients with severe haemolysis due to pyruvate kinase (PK) deficiency.[ncbi.nlm.nih.gov] The hyperlipidemia resolved with hypertransfusion therapy.[ncbi.nlm.nih.gov] She is doing well with mild splenomegaly.[ncbi.nlm.nih.gov]

  • Aagenaes Syndrome

    […] and symptoms: Main signs and symptoms include abdominal pain , acholic stools, fatigue , hepatomegaly, hyperlipidemia , lymphedema, nausea , vomiting , multiple lipomas , splenomegaly[xpertdox.com] […] skin pigmentation Abnormality of pigmentation Pigmentary changes Pigmentary skin changes Pigmentation anomaly [ more ] 0001000 Multiple lipomas Multiple fatty lumps 0001012 Splenomegaly[rarediseases.info.nih.gov] Signs and symptoms: Main signs and symptoms include abdominal pain , acholic stools, fatigue , hepatomegaly, hyperlipidemia , lymphedema, nausea , vomiting , multiple lipomas[xpertdox.com]

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