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16 Possible Causes for Hyperlipidemia Type 5, Osteopenia and Osteoporosis, Progressive Polyneuropathy

  • Chronic Alcoholism

    The concept of "structural plasticity" has emerged as a potential mechanism in neurodegenerative and psychiatric diseases such as drug abuse, depression, and dementia. Chronic alcoholism is a progressive neurodegenerative disease while the person continues to abuse alcohol, though clinical and imaging studies show[…][ncbi.nlm.nih.gov]

  • Diabetes Mellitus

    BACKGROUND: Type 2 Diabetes Mellitus is a serious metabolic disease that is often associated with vascular complications. There are 1.9 million people living with Diabetes in Ethiopia; diabetes mellitus is found to be the ninth leading cause of death related to its complications. Although the rate of vascular[…][ncbi.nlm.nih.gov]

  • Multiple Myeloma

    […] to multiple myeloma The initial presentation occasionally is a polyneuropathy when it is part of a POEMS syndrome (mostly the sclerotic form).[radiopaedia.org] Fractures may occur if plasma cell tumors cause loss of bone density ( osteopenia or osteoporosis ) and weaken bones.[merckmanuals.com] Bisphosphonates (alendronate or zoledronic acid) have been shown to improve bone mineral density in MGUS patients with osteopenia/osteoporosis or osteoporotic fractures (grade[doi.org]

  • Waldenstrom Macroglobulinemia

    Neuropathy is typically slowly progressive, distal, symmetrical, and sensorimotor.[emedicine.medscape.com] POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes) also may be associated with Waldenström macroglobulinemia.[emedicine.medscape.com]

  • Neuronal Ceroid Lipofuscinosis

    Visual failure was noticed at 6 years of age, but thereafter disease progression was atypical.[ncbi.nlm.nih.gov] […] due to hepatic triglyceride lipase deficiency Hyperlipidemia type 3 Hyperlipoproteinemia type 1 Hyperlipoproteinemia type 3 Hyperlipoproteinemia type 4 Hyperlipoproteinemia[csbg.cnb.csic.es] Osteopenia and osteoporosis are common in adults.[ncbi.nlm.nih.gov]

  • Diabetic Pseudotabes

    Most common complication of chronic renal failure Usually painless, progressive, symmetric sensorimotor peripheral polyneuropathy Sometimes burning, cramping, crawling, itching[quizlet.com] Diabetic Neuropathy General features: Hyperglycemia, hyperlipidemia, disordered insulin metabolism Affects greater than 5% of USA population 10% have Type I diabetes (autoimmune[neurodiffdx.com] Osteopenia (osteoporosis) develops as a rule as the initial unspecified radiological symptom on the foot. It may occur as part of generalised osteoporosis.[musculoskeletalkey.com]

  • Propionic Acidemia

    […] demyelination, which results in progressive neurologic dysfunction, includ-ing pyramidal signs, polyneuropathy, bulbar symptoms, ataxia, or even psychiatric symptoms in adult[docslide.us] […] due to hepatic triacylglycerol lipase deficiency Hyperlipoproteinemia type 1 Hyperlipoproteinemia type 3 Hyperlipoproteinemia type 5 Hyperlysinemia Hypermethioninemia due[se-atlas.de] Osteoporosis or osteopenia have only been documented in one patient.[flipper.diff.org]

  • Hypergonadotropic Hypogonadism-Cataract Syndrome

    Two sisters with mental retardation, cataract, ataxia, progressive hearing loss, and polyneuropathy. J Med Genet 1991 ; 28 : 884 –5.[jmg.bmj.com] type 3 Alpha-thalassemia x-linked intellectual disability syndrome Goblet cell carcinoid Myotonic dystrophy type 2 Familial partial lipodystrophy 5-alpha reductase deficiency[checkrare.com] Osteopenia and osteoporosis are both characterized by a reduced bone mass and increased susceptibility to bone fracture.[bloodjournal.org]

  • Glutamate Formiminotransferase Deficiency

    […] characterized by severe motor retardation and progressive scoliosis.[amp.pharm.mssm.edu] […] due to hepatic triglyceride lipase deficiency Hyperlipidemia type 3 Hyperlipoproteinemia type 1 Hyperlipoproteinemia type 3 Hyperlipoproteinemia type 4 Hyperlipoproteinemia[csbg.cnb.csic.es] Generalized osteopenia leading to fractures during childhood, with osteoporosis later in life, has also been reported.[pliem.co.za]

  • Oculorenocerebellar Syndrome

    Opthalmoplegia progressive external scoliosis[?] Optic atrophy opthalmoplegia ptosis deafness myopia[?] Optic atrophy polyneuropathy deafness[?][encyclopedia.kids.net.au] type 3 Hyperlipoproteinemia type 5 Hyperlysinemia Hypermethioninemia due to S-adenosylhomocysteine hydrolase deficiency Hypermobile Ehlers-Danlos syndrome Hyperostosis corticalis[rarediseases.info.nih.gov] […] and sparse hair M #259770 Osteoporosis-pseudoglioma syndrome OOM #234200 Pantothenate kinase-associated neurodegeneration A #168600 Parkinson Disease A #616361 Parkinson[biochemgenetics.ca]

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