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241 Possible Causes for Hypernatremia, Polyuria

  • Nephrogenic Diabetes Insipidus

    The polyuria did not respond to desmopressin, and subsequent correction of his polyuria and hypernatraemia after normalization of plasma potassium confirmed the diagnosis[ncbi.nlm.nih.gov] The patient was found to have profound hypernatremia and severe hypercalcemia with normal parathyroid and vitamin D serum levels.[ncbi.nlm.nih.gov] Investigations revealed persistent hypernatremia and deranged renal functions. Diagnostic work-up was suggestive of nephrogenic diabetes insipidus (NDI).[ncbi.nlm.nih.gov]

  • Diabetes Insipidus

    Several months after delivery, discontinuation of desmopressin resulted in recurrence of her polyuria.[ncbi.nlm.nih.gov] Hypernatremia was corrected by scheduled water intake with desmopressin administration.[ncbi.nlm.nih.gov] In follow-up she reported excellent control of polyuria and significant functional improvement.[ncbi.nlm.nih.gov]

  • Conn Syndrome

    […] pri·mar·y al·dos·ter·on·ism an adrenocortical disorder caused by excessive secretion of aldosterone and characterized by headaches, nocturia, polyuria, fatigue, hypertension[medical-dictionary.thefreedictionary.com] […] a cause of primary hyperaldosteronism and is the result of an aldosterone producing adenoma (APA) aldosterone secretion,supressed renin activity, hypernatremia, HTN hypokalemia[quizlet.com] It is often symptomless, but may present with symptoms of hypokalaemia – such as muscle weakness, fatigue, polyuria, cramps. 2/3 are due to a solitary mineralocorticoid producing[almostadoctor.co.uk]

  • Osmotic Diuretic

    POLYURIA after the release of obstructive uropathy is a clinical entity of considerable medical interest.[nejm.org] : fluid loss leads to significant dehydration and in the absence of adequate fluid replacement leads to hypernatremia.[pharmacology2000.com] The result is usually polyuria leading to dehydration if not managed in a timely and appropriate manner.[nataliescasebook.com]

  • Diabetic Ketotic Coma

    ), extreme acidosis (pH Signs and Symptoms – many gastric symptoms, probably protective against further ingestion of glucose osmotic diuresis (from hyperglycemia) causes polyuria[d3jonline.tripod.com] The initial symptoms of DKA include anorexia, nausea, vomiting, polyuria, and thirst. Abdominal pain, altered mental function, or frank coma may ensue.[accessmedicine.mhmedical.com] Hypernatremia often contributes additionally to plasma hyperosmolarity. The pathogenesis of these component abnormalities is considered.[ncbi.nlm.nih.gov]

  • Central Diabetes Insipidus

    This course indicates that not only the recovered renal response to arginine-vasopressin but also the immunomodulative effects of MMI might attribute to the improvement of polyuria[ncbi.nlm.nih.gov] The remaining hypernatremias were categorised as "non cDI".[ncbi.nlm.nih.gov] The patient reported polyuria and polydipsia that had started 2 months before admission.[hematologyandoncology.net]

  • Adrenal Cortex Hormone

    Sugar remains in the blood and often the body will try and remove this leading to a high sugar content in the urine, causing polyuria (passing of large volumes of urine) and[cancerindex.org] Monitor intake and output, serum glucose and electrolyte levels for abnormalities, especially hypokalemia and hypernatremia.[journals.lww.com] Hypertnsion, Hypokalemia (low levels of K), hypernatremia and Alkalosis. (Adenoma’s – Over production of Aldosterone).[biochemden.com]

  • Lithium

    The five single most common adverse effects leading to lithium discontinuation were diarrhoea (13%), tremor (11%), polyuria/polydipsia/diabetes insipidus (9%), creatinine[ncbi.nlm.nih.gov] KEYWORDS: Bipolar disorder; Drug reactions; Hypernatremia; Hypovolemia; Lithium; Nephrogenic diabetes insipidus[ncbi.nlm.nih.gov]

  • Iatrogenic Cushing's Disease

    Increased free cortisol Decreased serum ACTH Hypothesis: Iatrogenic Cushing’s syndrome Additional Learning issues: Pathophysiology of some Cushing’s disease clinical features Polyuria[medatrio.com] […] purple striae, proximal muscle weakness Other: increased risk of infection, increased cardiovascular risk, thromboembolism, bone loss, fractures, kidney stones, polydipsia, polyuria[hopkinsguides.com] , Lena Fels, Marion Schmicke, Reinhard Mischke In a 12-year-old male Labrador Retriever, presented due to other disease symptoms, clinical signs of hyperadrenocorticism (polyuria[read.qxmd.com]

  • Cushing's Disease

    Cushing's disease is hypercortisolaemia secondary to an adrenocorticotrophic hormone secreting pituitary adenoma. Primary management is almost always surgical, with limited effective medical interventions available. Adjuvant therapy in the form of radiation is gaining popularity, with the bulk of the literature related[…][ncbi.nlm.nih.gov]

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