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11 Possible Causes for Hypernatremia, Supraclavicular Fat Pads

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  • Iatrogenic Cushing's Disease

    Individuals with Cushing syndrome can develop moon facies, facial plethora, supraclavicular fat pads, buffalo hump, truncal obesity, and purple striae, as shown in the image[emedicine.medscape.com] Common: centripetal obesity with dorsocervical and supraclavicular fat pads, facial plethora and "moon face," fatigue, hyperglycemia, hypertension, mood lability, easy bruisability[hopkinsguides.com]

  • Adrenal Cortex Hormone

    Monitor intake and output, serum glucose and electrolyte levels for abnormalities, especially hypokalemia and hypernatremia.[journals.lww.com] Hypertnsion, Hypokalemia (low levels of K), hypernatremia and Alkalosis. (Adenoma’s – Over production of Aldosterone).[biochemden.com] Typical mineralocorticoid side-effects are hypertension (abnormally high blood pressure), hypokalemia (low potassium levels in the blood), hypernatremia (high sodium levels[en.wikipedia.org]

  • Cushing's Disease

    Individuals with Cushing syndrome can develop moon facies, facial plethora, supraclavicular fat pads, buffalo hump, truncal obesity, and purple striae, as shown in the image[emedicine.medscape.com] fat pads (buffalo hump) Usually, very slender distal extremities and fingers Muscle wasting and weakness are present.[merckmanuals.com] At baseline and at months 6 and 12, a reviewer at each site assessed patients for signs of hypercortisolism (facial rubor and supraclavicular and dorsal fat pads) by scoring[nejm.org]

  • Adrenocortical Carcinoma

    pads.[symptoma.com] The majority of patients with functional tumors shows symptoms of Cushing syndrome including truncal obesity, striae, malar flushing, supraclavicular and dorsocervical fat[symptoma.com]

  • ACTH-Secreting Pituitary Adenoma

    fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis[radiopaedia.org] Weight gain (with centripetal distribution, buffalo-hump, supraclavicular fat pad), arterial hypertension, ecchymoses and purple striae on flanks and lower abdomen are all[primarycare.imedpub.com] Typically, patients have the following clinical features 6 : rounded face, sometimes described as 'moon-shaped' progressive centripetal obesity and weight gain prominent supraclavicular[radiopaedia.org]

  • Secondary Aldosteronism

    […] hydroxycortisol -Aldosterone to renin ration -captopril supression test (if aldo.levels remain unchanges after captoril adm. diagnosis can be made) -biochemistry: *hypokalemia *hypernatremia[quizlet.com] Weight gain, glucose intolerance, striae, skin thinning, increase in cervical, supraclavicular fat pad, facial plethora, muscle weakness, or osteoporosis in an obese patient[thecurbsiders.com] […] pressure natriuresis (other mechanisms may be responsible, although how these operate remains unclear) compensatory diuresis “escape” from edema and formation and frank hypernatremia[amboss.com]

  • Cushing Syndrome

    Cortisol can also exhibit mineralocorticoid activity in high concentrations, worsening the hypertension and leading to hypokalemia (common in ectopic ACTH secretion) and hypernatremia[en.wikipedia.org] Features more specific to Cushing's syndrome include proximal muscle weakness, supraclavicular fat pads, facial plethora, violaceous striae, easy bruising, and premature osteoporosis[bestpractice.bmj.com] fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis[radiopaedia.org]

  • Ectopic ACTH Syndrome

    Laboratory assessments showed hyperglycemia, hypernatremia, severe hypocalemia, metabolic alkalosis and low urinary osmolarity, which persisted after water deprivation test[imed.pub] fat pad, sometimes known as a 'buffalo hump' purple skin striae easy skin bruising acanthosis nigricans proximal myopathy depression and other mood disorders osteoporosis[radiopaedia.org] Presentation Truncal obesity, supraclavicular fat pads, buffalo hump, weight gain. Facial fullness, moon facies, facial plethora. Proximal muscle wasting and weakness.[patient.info]

  • Adrenal Cortical Adenoma

    As a result of hypernatremia, hypokalemic alkalosis, and other related mechanisms, patients may develop fatigue, weakness, headaches, tetany, and paresthesias.[symptoma.com] The association with facial rounding (“moon face”) and supraclavicular and dorsocervical fat pads (“buffalo hump”) is less strong as these can be seen in obesity from other[cancertherapyadvisor.com] […] normal adrenal cortex Difficult to differentiate ACA from normal adrenal cortex in adrenal core needle biopsies Laboratory Hyperaldosteronism/Conn's syndrome: aldosterone, hypernatremia[pathologyoutlines.com]

  • Diabetic Pseudotabes

    Gross derangements of volume and electrolytes (e.g. hypokalemia, hypernatremia) should be corrected.[spectrum.diabetesjournals.org] Skin (plethora; hirstutism; ance; telengectasia); Moon facies; Eyes (visual fields - fundi (HTN DM Papilloedema); Mouth thrush; Neck - supraclavicular fat pads; acanthosis[freezingblue.com]

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