Hyperostosis: Causes & Reasons

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Possible Causes for Hyperostosis

Diffuse Idiopathic Skeletal Hyperostosis

Hyperostosis ANKYLOSING VERTEBRAL HYPEROSTOSIS WITH TYLOSIS Forestier's Disease Ankylosing hyperostosis [wikidata.org]

Neurological complications are rare in diffuse idiopathic skeletal hyperostosis. [ncbi.nlm.nih.gov]

A rare case of retro-odontoid pseudotumor combined with diffuse idiopathic skeletal hyperostosis is presented. [ncbi.nlm.nih.gov]

Camurati-Engelmann Syndrome

However, the skull hyperostosis is progressive, and cranial nerve compression often recurs. Corticosteroids may delay skull hyperostosis and cranial nerve impingement. [ncbi.nlm.nih.gov]

Clinical description Most of the clinical signs are related to hyperostosis and sclerosis. [orpha.net]

Calvarial hyperostosis can lead to increased intracranial pressure and headaches. [ncbi.nlm.nih.gov]

Van Buchem Disease

Prevention - Hyperostosis corticalis generalisata Not supplied. Diagnosis - Hyperostosis corticalis generalisata Not supplied. [checkorphan.org]

Signs and Symptoms Abnormal cortical bone morphology Abnormality of the clavicle Craniofacial hyperostosis Increased bone mineral density Mandibular prognathia Facial palsy [familydiagnosis.com]

Hyperostosis corticalis generalisata familiaris | definition of hyperostosis corticalis generalisata familiaris by Medical dictionary https://medical-dictionary.thefreedictionary.com [medical-dictionary.thefreedictionary.com]

Meningioma

BACKGROUND: Several hypotheses have been proposed regarding the mechanisms underlying meningioma-related hyperostosis. [ncbi.nlm.nih.gov]

It will also show perilesional edema, hyperostosis and intratumoral calcification if present. [symptoma.com]

Historically a number of features were observed, including: enlarged meningeal artery grooves hyperostosis or lytic regions calcification displacement of calcified pineal [radiopaedia.org]

Hypervitaminosis A

Dysphagia can result from anterior cervical hyperostosis. A role for hypervitaminosis A in the genesis of hyperostosis has long been suspected. [ncbi.nlm.nih.gov]

Radiographs may show hyperostosis affecting long bones, especially affecting middle of the shafts. It is different from cortical hyperostosis. [nhp.gov.in]

[…] premature fusion of ossification centers separation of cranial sutures hepatosplenomegaly tendinous/ligamentous calcifications Differential diagnosis infantile cortical hyperostosis [radiopaedia.org]

Endosteal Hyperostosis

We present a father and daughter with endosteal hyperostosis. [jmedicalcasereports.biomedcentral.com]

MalaCards organs/tissues related to Endosteal Hyperostosis, Autosomal Dominant: 40 Bone, Cortex, Endothelial [malacards.org]

PMID: 8030669 Autosomal dominant hyperostosis/osteosclerosis with high serum alkaline phosphatase activity. [pubmed.ncbi.nlm.nih.gov]

Tumoral Calcinosis

[…] long bone lesions with hyperostosis. [ncbi.nlm.nih.gov]

*/blood Hyperostosis*/genetics Hyperostosis*/pathology Hyperostosis*/therapy Hyperostosis, Cortical, Congenital*/blood Hyperostosis, Cortical, Congenital*/genetics Hyperostosis [ncbi.nlm.nih.gov]

This report describes two sisters and an unrelated girl with hyperostosis and hyperphosphatemia and reviews previous cases in the literature. [pediatrics.aappublications.org]

Melorheostosis

Computed tomography scans showed multiple areas of classic candle wax-like hyperostosis and narrowing or disappearance of the medullary cavity. [ncbi.nlm.nih.gov]

Radiographs demonstrated endosteal hyperostosis, which were consistent with a mixed picture of melorheostosis and osteopoikilois. [ncbi.nlm.nih.gov]

hyperostosis at the level of right shoulder girdle involving the humerus. [ncbi.nlm.nih.gov]

Osteophyte

Hyperostosis of the spine in an adult population. Its relation to hyperglycaemia and obesity. [ncbi.nlm.nih.gov]

Osteophytes are bony outgrowths usually found in the context of osteoarthritis and diffuse idiopathic skeletal hyperostosis (DISH). [ncbi.nlm.nih.gov]

Diffuse idiopathic skeletal hyperostosis is more frequent in men than in women. [journals.lww.com]

Infantile Cortical Hyperostosis

Hyperostosis, Congenital Cortical Hyperostosis, Cortical Congenital Hyperostosis, Infantile Cortical Infantile Cortical Hyperostoses Infantile Cortical Hyperostosis Syndrome [decs.bvs.br]

hyperostosis [ hi″per-os-to´sis ] excessive growth of bony tissue. adj., adj hyperostot´ic. frontal internal hyperostosis ( hyperostosis fronta´lis inter´na ) a new formation [medical-dictionary.thefreedictionary.com]

Congenital Hyperostoses, Cortical Congenital Hyperostosis, Cortical Cortical Congenital Hyperostoses Cortical Congenital Hyperostosis Cortical Hyperostoses, Congenital Cortical [decs.bvs.br]

Carcinomatous Polyarthritis

Costochondritis Costosternal syndrome CREST syndrome Crohn’s Disease Cryoglobulinemia Degenerative joint disease Dermatomyositis Diabetic finger sclerosis Diffuse idiopathic skeletal hyperostosis [buyprovailencheap.org]

[…] syndrome Syphilitic arthritis Diabetic finger sclerosis Systemic lupus erythematosus (SLE) Metastatic carcinomatous arthritis Takayasu’s arthritis Diffuse idiopathic skeletal hyperostosis [erheumatoidarthritissymptoms.com]

Corticosteroid-induced osteoporosis Costosternal syndrome CREST syndrome Cryoglobulinemia Degenerative joint disease Dermatomyositis Diabetic finger sclerosis Diffuse idiopathic skeletal hyperostosis [americanimagingpr.com]

Familial Teutschlaender Disease

Name Tumoral Calcinosis, Hyperphosphatemic, Familial, 1 Synonyms CALCINOSIS, TUMORAL, WITH HYPERPHOSPHATEMIA, CORTICAL HYPEROSTOSIS WITH HYPERPHOSPHATEMIA, HYPEROSTOSIS WITH [mousephenotype.org]

Keywords Calcinosis Phosphate Hyperostosis Proximal tubule Abbreviations HFTC Hyperphosphatemic familial tumoral calcinosis HHS Hyperphosphatemia-hyperostosis syndrome ppGalNAc-T3 [link.springer.com]

Herein,we sought to identify the genetic cause of hyperphosphataemia and tibial hyperostosis in a 19-year-old girl of Colombian origin. [diva-portal.org]

Familial Normophosphatemic Tumoral Calcinosis

HFTC hyperphosphatemia hyperostosis hyperphosphatemia hyperostosis syndrome hyperphosphatemia tumoral calcinosis primary hyperphosphatemic tumoral calcinosis Carmichael KD [ghr.nlm.nih.gov]

Hyperostosis. [ncbi.nlm.nih.gov]

Mikati MA, Melhem RE, Najjar SS: The syndrome of hyperostosis and hyperphosphatemia. J Pediatr 1981, 99: 900–904. PubMed CrossRef Google Scholar 44. [link.springer.com]

Chronic Recurrent Multifocal Osteomyelitis

Numerous authors have suggested that CRMO and synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome lie along the same clinical spectrum. [ncbi.nlm.nih.gov]

[…] but association with other auto-inflammatory diseases such as inflammatory bowel disease (IBD), psoriasis, Wegener's disease, arthritis and synovitis, acne, pustulosis, hyperostosis [ncbi.nlm.nih.gov]

It is associated with several pathologic processes including psoriasis, palmoplantar pustulosis, and SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, and osteitis [ncbi.nlm.nih.gov]

Primary Hypertrophic Osteoarthropathy

X-rays showed destruction and osteoproliferative changes of the metatarsal bones with periostal hyperostosis close to the talus. [ncbi.nlm.nih.gov]

A lateral radiograph of the skull revealed hyperostosis of the skull bones; however, the sella turcica appeared normal [Figure 5]. [doi.org]

A skull X-ray revealed calvarial hyperostosis and a normal sellar outline. Family history was negative. [edmcasereports.com]

Osteitis

Plain radiography demonstrated hyperostosis with subperiosteal erosions in the right tibia. [ncbi.nlm.nih.gov]

Numerous authors have suggested that CRMO and synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome lie along the same clinical spectrum. [ncbi.nlm.nih.gov]

PAO is sometimes regarded as a variant of synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome. [ncbi.nlm.nih.gov]

Leontiasis due to Leprosy

Plain radiography and helical computed tomography revealed generalized hyperostosis obliterating the maxillary and sphenoidal sinuses and 2 exuberant bony masses arising from [ncbi.nlm.nih.gov]

Calvarial Doughnut Lesions - Bone Fragility Syndrome

Infantile cortical hyperostosis is described under a separate heading because of the selective involvement of the mandible in this disease. [rrnursingschool.biz]

Caffey Infantile Hyperostosis ; 104. Osteoectasia with hyperphosphatasia ; 105. Endosteal Hyperostosis, van Buchem type ; 106. [amazon.de]

Caffey Infantile Hyperostosis 104. Osteoectasia with hyperphosphatasia 105. Endosteal Hyperostosis, van Buchem type 106. Diaphyseal dysplasia, Camurati Engelmann 107. [axon.es]

Acquired Osteosclerosis

Radiology 119:55–9 CrossRef Google Scholar Resnick D, Shapiro RF, Wiesner KB et al (1978c) Diffuse idiopathic skeIetaI hyperostosis (DISH) (ankylosing hyperostosis of Forestier [link.springer.com]

[DISH] ( ICD-10-CM Diagnosis Code M48.1 Ankylosing hyperostosis [Forestier] 2016 2017 2018 2019 Non-Billable/Non-Specific Code Applicable To Diffuse idiopathic skeletal hyperostosis [icd10data.com]

Osteosclerosis Osteomyelitis - Avascular necrosis - Paget's disease of bone - Algoneurodystrophy - Osteolysis - Infantile cortical hyperostosis Chondropathies Juvenile [bionity.com]

Craniometadiaphyseal Dysplasia

The craniofacial bones were noted to have salient sclerosis and hyperostosis ( Fig. 2 ). [e-aps.org]

OR WITHOUT ANOSMIA; HH17 Low match CRANIOMETAPHYSEAL DYSPLASIA Craniometaphyseal dysplasia (CMD) is a very rare genetic bone disease characterized by progressive diffuse hyperostosis [mendelian.co]

It is characterized by sclerosis of bones, especially the skull base and craniofacial bones with generalized hyperostosis. [jiaomr.in]

Paget Disease of the Bone Type 5

PDB5 clinical manifestations include short stature, progressive long bone deformities, fractures, vertebral collapse, skull enlargement, and hyperostosis with progressive [uniprot.org]

Juvenile Paget disease is also known as osteoectasia with hyperphosphatasia, fragile bones and macrocranium, hyperostosis corticalis deformans juvenile, chronic idiopathic [roentgenrayreader.blogspot.com]

Title Other Names: JPD; Hyperostosis corticalis deformans juvenilis; Hyperphosphatasia, familial idiopathic; JPD; Hyperostosis corticalis deformans juvenilis; Hyperphosphatasia [rarediseases.info.nih.gov]

Lenz-Majewski Syndrome

Patients have multiple radiographic abnormalities due to progressive generalized hyperostosis that affects the cranium, vertebrae, and diaphyses of tubular bones, leading [malacards.org]

The life-threatening complication was related to progressive craniovertebral hyperostosis that rapidly exacerbated during early childhood. [ncbi.nlm.nih.gov]

Skeletal changes included calvarial hyperostosis, sclerosis of the skull base, an enlarged, sclerotic mandible, broad clavicles and ribs, and diaphyseal undermodeling of the [ncbi.nlm.nih.gov]

Periostitis

Goldbloom syndrome is an idiopathic periosteal hyperostosis associated with dysproteinemia and elevated inflammatory parameters. [ncbi.nlm.nih.gov]

Caffey disease : Also known as infantile cortical hyperostosis. Self-limited, painful periostitis of long bones. Clavicular and mandibular involvement suggestive. [roentgenrayreader.blogspot.com]

X-ray showed periosteal hyperostosis. A short cycle of corticosteroids led to rapid recovery of symptoms and disappearance of bone changes. [ncbi.nlm.nih.gov]

Carpotarsal Osteochondromatosis

Ehlers-Danlos syndrome, spondylocheirodysplastic type Ehlers-Danlos/osteogenesis imperfecta syndrome Eiken syndrome Ellis Van Creveld syndrome Enchondromatosis Endosteal hyperostosis [se-atlas.de]

Caffey disease, CAHMR syndrome, Calabro syndrome, Calcifying Epi the lial Odontogenic Tumor, Calciphylaxis, California encephalitis, Calloso-genital dysplasia, Calvarial hyperostosis [yumpu.com]

[…] diaphyseal involvement Diaphyseal dysplasia Camurati Engelmann AD Diaphyseal dysplasia with anemia (Ghosal) AR Craniodiaphyseal dysplasia AR Lenz Majewski dysplasia Endosteal hyperostosis [gamuts.isradiology.org]

Kissing Spine

Fibrous articulations, ligaments, or entheses (sites of tendon or ligament attachment to bone) are involved in diffuse idiopathic skeletal hyperostosis, ossification of the [radiology.rsna.org]

Hyperostosis of lumbar spinous process: a radiological feature in a young acromegalic. J Manip Physiol Ther. 1987; 10 (3):111–115. [ PubMed ] [ Google Scholar ] 18. [ncbi.nlm.nih.gov]

Spondylosis Muscle Strain Spondylolisthesis Fracture of the spinous process Vertebral (e.g. lumbar) compression fractures Infectious etiologies of the spine Proliferative hyperostosis [physio-pedia.com]

Postaxial Oligodactyly, Tetramelic

[…] with predominant vertebral and costal involvement Dysostosis, Stanescu type Dysplasia epiphysealis hemimelica Dysplasia of head of femur, Meyer type Dysplastic cortical hyperostosis [se-atlas.de]

[…] lait spots, multiple * Caffey disease * CAHMR syndrome * Calabro syndrome * Calcifying Epithelial Odontogenic Tumor * Calciphylaxis * Calloso-genital dysplasia * Calvarial hyperostosis [medicalgeek.com]

PMM2-CDG Pachydermoperiostosis Pachygyria-intellectual disability-epilepsy syndrome Pacman dysplasia Pai syndrome Pallister-Hall syndrome Pancreatic insufficiency-anemia-hyperostosis [se-atlas.de]

Osteitis Condensans Ilii

Osteitis condensans ilii, also known as osteopathia condensans ilii or hyperostosis triangularis ilii in Germany, is characterized by benign sclerosis of the ilium adjacent [radiopaedia.org]

Bilateral Symmetric Triangle shaped areas of sclerosis of lower half of ilium Normal joint margins Normal Joint space ___ AKA osteitis condensans ilii Hyperostosis triangularis [quizlet.com]

[…] pulmonary osteoarthropathy Nonossifying fibroma Pseudarthrosis Stress fracture Fibrous dysplasia Monostotic Polyostotic Skeletal fluorosis bone cyst Aneurysmal bone cyst Hyperostosis [en.wikipedia.org]

Osteopathia Striata

It presents typical radiological changes of cortical hyperostosis distributed along a sclerotome with variable associated cutaneous and clinical features. [ncbi.nlm.nih.gov]

Because the disorder may resemble several other conditions, the differential diagnosis should include osteopoikilosis, the autosomal dominant form of osteopetrosis, and hyperostosis [ncbi.nlm.nih.gov]

[…] deletions in the X linked gene, WTX, and is characterized by sclerotic striations of the metaphyses and diaphyses of long bones, pelvis, and scapula, along with craniofacial hyperostosis [ncbi.nlm.nih.gov]

Osteitis Fibrosa Disseminata

Kniest-Stickler dysplasia group Langer mesomelic dysplasia syndrome Lenz-Majewski hyperostosis syndrome Leri-Weill dyschondrosteosis Melnick-Needles syndrome Metachondromatosis [healthprovidersdata.com]

[…] osteodystrophy Dysplasia epiphysealis hemimelica Furst-Ostrum syndrome Hajdu-Cheney syndrome Hepatic osteodystrophy Hyperphosphatasia-osteoectasia syndrome Infantile cortical hyperostosis [icd9data.com]

[…] dysplasia Dysplasia epiphysealis hemimelica Furst-Ostrum syndrome Hajdu-Cheney syndrome Hepatic osteodystrophy Hyperphosphatasia-osteoectasia syndrome Infantile cortical hyperostosis [healthprovidersdata.com]

Osteomesopyknosis

MalaCards based summary : Osteomesopyknosis, also known as axial osteosclerosis, is related to hyperostosis. [malacards.org]

[…] striata Radiodense SP XLD isolated with striations on all cranial sclerosis bones with cranial sclerosis Sponastrime Striated AR dysplasia metaphysis Melorheostosis Flowing SP hyperostosis [medical-dictionary.thefreedictionary.com]