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37 Possible Causes for Hyperostosis, Narrowing of Medullary Canal, Thickened Cortices

  • Camurati-Engelmann Syndrome

    However, the skull hyperostosis is progressive, and cranial nerve compression often recurs. Corticosteroids may delay skull hyperostosis and cranial nerve impingement.[ncbi.nlm.nih.gov] Certain bone regions (specifically, the endosteal and periosteal surfaces) become abnormally thickened and hardened, which in turn narrows the medullary canal.[encyclopedia.com] Radiographic studies in the two girls demonstrated not only diaphyseal dysplasia (cortical thickening of the diaphyses) resembling that of progressive diaphyseal dysplasia[ncbi.nlm.nih.gov]

  • Melorheostosis

    The lesions of the cortex are progressive and may result in narrowing of the medullary canal and stenosis of an adjacent lumen, foramen, or of the spinal canal .[boneandspine.com] Melorheostosis Leri’s Disease, Flowing Periosteal Hyperostosis One of a group of sclerosing bone disorders Rare Cause is unknown Produces thickening of the endosteum and periosteum[learningradiology.com] Macroscopy On gross examination of the affected bones, the periosteal and endosteal surfaces are irregular, and the bones display thickened cortices.[humpath.com]

  • Osteosclerosis

    Radiographically, affected members exhibit generalized, symmetrically diffuse endosteal hyperostosis of the long bones and skull with narrow medullary cavities and loss of[ncbi.nlm.nih.gov] medullary canals.[dx.doi.org] Radiographic findings include either diffusely or patchy increased bone density with cortical thickening in the hematopoietic bones (vertebrae, pelvis, ribs, and the long[posterng.netkey.at]

  • Van Buchem Disease

    Prevention - Hyperostosis corticalis generalisata Not supplied. Diagnosis - Hyperostosis corticalis generalisata Not supplied.[checkorphan.org] […] of the medullary canal.[ncbi.nlm.nih.gov] UniProtKB/Swiss-Prot : 76 Van Buchem disease 2: VBCH2 is an autosomal dominant sclerosing bone dysplasia characterized by cranial osteosclerosis, thickened calvaria and cortices[malacards.org]

  • Kenny-Caffey Syndrome Type 1

    Camurati-Engelmann Syndrome : A musculoskeletal syndrome leading to enhanced bone formation, hyperostosis and sclerosis of the diaphyses of the long bones.[accessanesthesiology.mhmedical.com] Initially begins in the diaphyses and it extends to the metaphyses, sparing the epiphyses. 16,20,21 As a consequence it can be seen a narrowing of the medullary canal with[elsevier.es] Clinical features include cortical thickening and medullary stenosis of the tubular bones, delayed closure of fontanels, defective dentition, small eyes with hypermetropia[malacards.org]

  • Sclerosteosis Type 2

    […] hypertelorism, wide and dense clavicles-ribs, sclerotic calvarium, enlarged and sclerotic mandible, sclerotic vertebral end plates and pedicles, sclerotic pelvic bones, cortical hyperostosis[iofbonehealth.org] […] of medullary canal; erlenmeyer flask defect of the bone; clubfoot (genu varus and valgus deformities); relative muscle weakness, especially in pelvic girdle; atrophic muscle[encyclopedia.com] Alternative names BEER CDD Cortical hyperostosis with syndactyly see all Function Negative regulator of bone growth.[abcam.com]

  • Craniodiaphyseal Dysplasia

    Imbalance will lead to conditions such as osteoporosis or hyperostosis. Osteoblasts build bone, becoming embedded in bone matrix as mature osteocytes.[ncbi.nlm.nih.gov] […] of medullary canal; erlenmeyer flask defect of the bone; clubfoot (genu varus and valgus deformities); relative muscle weakness, especially in pelvic girdle; atrophic muscle[encyclopedia.com] The long bones show extreme asymmetric hyperostosis and sclerosis of the diaphyses and evidence of a modelling defect in the metaphyses.[ncbi.nlm.nih.gov]

  • Schwartz-Lelek Syndrome

    Physical Fitness) Cleanses & Detoxifying Katz Syndrome “Katz Syndrome” In our body, the dis-order, Katz Syndrome is the allopathic name of a shortness of stature , cranial hyperostosis[wellnessadvocate.com] , sclerotic medullary canal Type III: Anterior bowig with a cystic lesion or prefracture Type IV: Anterior bowing with a frank fracture and pseudarthrosis usually involving[flinders.edu.au] ., conditions with increased bone density and cortical thickening (van Buchem and Worth type of endosteal hyperostosis, sclerosteosis, Camurati-Engelmann disease, hyperphosphatasia[rrnursingschool.biz]

  • Frontometaphyseal Dysplasia

    This condition is characterized by hyperostosis of the skull and prominence of the supraorbital ridges; long bones have flared metaphyses.[ncbi.nlm.nih.gov] […] of medullary canal; erlenmeyer flask defect of the bone; clubfoot (genu varus and valgus deformities); relative muscle weakness, especially in pelvic girdle; atrophic muscle[encyclopedia.com] Roentgenograms show supraorbital hyperostosis, antegonial notching of the mandible, flared ilia, contraction of the midpelvis, flattened vertebrae, deformities of the ribs[ncbi.nlm.nih.gov]

  • Van Buchem Disease Type 2

    References Beals RK (1976) Endosteal hyperostosis.[link.springer.com] […] of medullary canal; erlenmeyer flask defect of the bone; clubfoot (genu varus and valgus deformities); relative muscle weakness, especially in pelvic girdle; atrophic muscle[encyclopedia.com] cortices of long bones.[iofbonehealth.org]

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