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2,421 Possible Causes for Hyperpigmentation, Hypertension

  • Acromegaly

    Increased mortality has been related to cardiovascular events that could be linked to these hormones and patients suffer from high rates of diabetes and hypertension.[ncbi.nlm.nih.gov] […] eyelids Increased body hair ( hypertrichosis ), excessive sweating ( hyperhidrosis ), and oily skin ( seborrhoea ) Increased number of skin tags and darkening of the skin ( hyperpigmentation[dermnetnz.org] […] vocal cords, resulting in a characteristic thick, deep voice and slowing of speech skull, frontal bossing mandible: prognathism with gaping teeth skin changes hypertrichosis hyperpigmentation[radiopaedia.org]

  • Adrenal Insufficiency

    He had episodes of hypertensive crises, for which he was thoroughly investigated and it was found to be due to autonomic instability.[ncbi.nlm.nih.gov] PATIENT AND METHODS: The patient was born with hyperpigmentation, micropenis, penoscrotal hypospadias, and mild cryptorchidism.[ncbi.nlm.nih.gov] […] several AI patients are frequently exposed to relative glucocorticoid excess potentially leading to develop chronic complications, such as diabetes mellitus, dyslipidemia, hypertension[ncbi.nlm.nih.gov]

  • Malignant Neoplasm

    OBJECTIVES: To investigate the cause of reduced malignant neoplasm-related mortality in hypertensive outpatients.[ncbi.nlm.nih.gov] 1955, individuals with Cronkhite-Canada syndrome, which presents at an average age of 59 years, exhibit multiple intestinal polyps and ectoderm abnormalities, including hyperpigmentation[emedicine.medscape.com] Yuan and Vinicio de Jesus Perez , Endothelial dysfunction in pulmonary arterial hypertension: an evolving landscape (2017 Grover Conference Series) , Pulmonary Circulation[doi.org]

  • Systemic Scleroderma

    Renal crisis can be effectively managed when hypertension is aggressively controlled with angiotensin converting enzyme (ACE) inhibitors.[ncbi.nlm.nih.gov] […] severe type of systemic scleroderma with hyperpigmentation, especially male and older patients, and in unexposed portions of the female group without hyperpigmentation.[ncbi.nlm.nih.gov] [HT], pulmonary arterial hypertension [PAH] and pulmonary fibrosis [PF]).[ncbi.nlm.nih.gov]

  • Diffuse Scleroderma

    Twelve patients (35% of the total cohort) had pulmonary hypertension defined as PAs of 30 mm Hg or greater.[ncbi.nlm.nih.gov] Skin can breakdown and discharge chalky material (calcium) Salt and pepper dyspigmentation ( hyperpigmentation and hypopigmentation ) Pruritus Rarer cutaneous features Morphoea[dermnetnz.org] During the subsequent 6 months, the patient developed lower limb oedema, which progressed to the hands and face, coupled with generalized pain and hyperpigmentation of skin[doi.org]

  • Cushing's Disease

    CONTEXT: Several studies have reported an association between idiopathic intracranial hypertension (IIH) and deficits of the hypothalamic-pituitary-adrenal (HPA) axis.[ncbi.nlm.nih.gov] The disease manifests with signs of CS (truncal and facial obesity and signs of hypercatabolism) as well as skin hyperpigmentation and/or neurological complications in some[orpha.net] Diabetes mellitus and hypertension were observed in 38.7 and 55.1% of patients, respectively.[ncbi.nlm.nih.gov]

  • Porphyria

    On admission, she was noted to have hyponatremia, tachycardia, and hypertension. Then, she had episodes of seizure and confusion.[ncbi.nlm.nih.gov] Symptoms are: blisters on areas of the skin exposed to the sun such as the face, arms, and hands followed by crusting and scarring; hyperpigmentation; increased hair growth[publichealth.va.gov] Chronic hypertension or chronic kidney disease can develop in a small minority.[patient.info]

  • Acute Hepatic Porphyria

    Content is provided from medical therapies to surgery on the patient with portal hypertension.[books.google.com] Secondary infections can cause areas of hypo- or hyperpigmentation or sclerodermatous changes and may result in the development of alopecia at sites of repeated skin damage[mayomedicallaboratories.com] Patients usually present with abdominal pain, impaired intestinal motility, neurological and psychiatric symptoms, hypertension, tachycardia, hyponatriemia and reddish urine[ncbi.nlm.nih.gov]

  • Hyperthyroidism

    KEYWORDS: Hashimoto's thyroiditis; hyperthyroidism; pregnancy; systolic arterial hypertension[ncbi.nlm.nih.gov] Reactive hyperpigmentation of the skin and mucous membranes may be found in Addison's disease and hyperthyroidism.[ncbi.nlm.nih.gov] Tachycardia, irregular pulse (in atrial fibrillation), dyspnea, orthopnea and peripheral edema (in heart failure) Cutaneous Onycholysis (Plummer nails), patchy or generalized hyperpigmentation[aafp.org]

  • Carcinoid Tumor

    Serotonin, for example, can lead to tachycardia and hypertensive crisis refractory to conventional treatment.[doi.org] Thymic carcinoid with cutaneous hyperpigmentation . Arch Intern Med 1985; 145 : 361–363. 32. Lokich JJ , Li F .[nature.com] Goals Prevention of Mediator release Preoperative Stress (use anxiolytic without histamine relating properties Response to intubation Inadequate analgesia Hypotension / Hypertension[openanesthesia.org]

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