Create issue ticket

520 Possible Causes for Hyperpigmentation, Iron Deficiency, Jaundice

  • Pernicious Anemia

    She was readmitted with jaundice and macrocytic anemia.[ncbi.nlm.nih.gov] Physical examination revealed hypotension and marked hyperpigmentation. Laboratory testing showed hyponatremia, hyperkaliemia and severe normocytic anemia.[ncbi.nlm.nih.gov] Biology of Iron-Deficiency Anemia An iron deficiency can also disrupt hemoglobin function, causing iron-deficiency anemia.[livestrong.com]

  • Vitamin B12 Deficiency

    We report an adolescent girl who presented with jaundice and weight loss for 6 months secondary to vitamin B12 deficiency, leading to megaloblastic anaemia.[ncbi.nlm.nih.gov] Hyperpigmentation as the first presentation of Vitamin B12 deficiency is rare.[ncbi.nlm.nih.gov] Adjacent To D51.9 D50.0 Iron deficiency anemia secondary to blood loss (chronic) D50.1 Sideropenic dysphagia D50.8 Other iron deficiency anemias D50.9 Iron deficiency anemia[icd10data.com]

  • Hemochromatosis

    Here we report the case of a 16-year-old Chinese boy, who was admitted with hepatalgia, jaundice, hyperpigmentation, and splenomegaly to our hospital.[ncbi.nlm.nih.gov] External genital hyperpigmentation was seen in one third of patients, and one fifth had hyperpigmentation of flexural folds, scars, and nipple areolae.[emedicine.com] deficiency anemia - ferritin Brittenham GM.[medlineplus.gov]

  • Acute Hepatic Porphyria

    […] nutrition 180 Nutritional disorders and their management 200 Clinical biochemistry of the gastrointestinal tract 214 Assessment of hepatic function and investigation of jaundice[books.google.com] Secondary infections can cause areas of hypo- or hyperpigmentation or sclerodermatous changes and may result in the development of alopecia at sites of repeated skin damage[mayomedicallaboratories.com] Inducing iron deficiency improves erythropoiesis and photo sensivity in congenital erythropoietic porphyria. Blood. 2015;126(2):257–261.[medcraveonline.com]

  • Porphyria

    ., and Thomson S. ( 1948 ) A case of chronic porphyria associated with recurrent jaundice. Quarterly Journal of Medicine 51: 123 - 137.[doi.org] Symptoms are: blisters on areas of the skin exposed to the sun such as the face, arms, and hands followed by crusting and scarring; hyperpigmentation; increased hair growth[publichealth.va.gov] And it is known that porphyria, an iron deficiency, which is thought to lie behind the vampire myth, has run in the Royal Family.[news.bbc.co.uk]

  • Erythropoietic Protoporphyria

    A 21-year-old Japanese man was admitted to our hospital because of severe abdominal pain and jaundice.[ncbi.nlm.nih.gov] After repetitive exposure, patients may present with lichenification, hypopigmentation, hyperpigmentation and scarring of the skin.EPP usually first presents in childhood,[en.wikipedia.org] These disorders are often associated with iron deficiency anaemia (IDA).[ncbi.nlm.nih.gov]

  • Cronkhite-Canada Syndrome

    Clinical examination revealed he was not jaundiced, pale, or cachectic. His abdomen was soft and not distended.[frontiersin.org] A 62-year-old Malaysian woman presented with a constellation of skin signs including alopecia, hyperpigmentation and nail dystrophy.[ncbi.nlm.nih.gov] Because of iron deficiency anemia and occult gastrointestinal bleeding, she underwent a colonoscopic examination. Colonoscopy revealed multiple broad-based polyps.[ncbi.nlm.nih.gov]

  • Primary Biliary Cirrhosis

    A 65-year-old male was admitted to our hospital with jaundice, pruritus, mild abdominal pain and darkening urine.[ncbi.nlm.nih.gov] Clinical features include 12 : pruritus (often the first symptom) jaundice skin hyperpigmentation, especially of arms and trunk xanthomata and xanthelasma due to hypercholesterolemia[radiopaedia.org] Iron deficiency anemia responds to oral iron supplements.[rarediseases.org]

  • Progressive Familial Intrahepatic Cholestasis

    RESULTS: Six patients who underwent PBD experienced short-term resolution of jaundice and pruritus.[ncbi.nlm.nih.gov] Physical exam Remarkable findings on examination include: Icterus Hepatosplenomegaly Hyperpigmentation Growth retardation Shiny nails The newborn with unexplainable cholestasis[symptoma.com] FOLR1 Neurodegeneration mit Eisenablagerungen Typ1 PANK2 Neurodegeneration with brain iron accumulation FTL, PLA2G6, PANK2 Neurofibromatose Typ1 NF1, NF1 Neuronopathy, distal[meduniwien.ac.at]

  • Thalassemia

    Clinical description Patients present with moderate to severe anemia, jaundice and splenomegaly.[orpha.net] As such, there may be generalized hyperpigmentation or “bronzing” of the skin, along with other expected physical findings in liver disease and congestive heart failure (CHF[clinicaladvisor.com] Red cell distribution width in iron deficiency anemia and β-thalassemia minor [letter]. Am J Clin Pathol. 2008 ; 130 : 313 – 314. 5..[doi.org]

Similar symptoms