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294 Possible Causes for Hyperpigmentation, Spironolactone

  • Acne Vulgaris

    Table 2 Summary of findings for spironolactone versus placebo 3.3.2 Spironolactone versus Cimetidine Three trials compared spironolactone with cimetidine using different daily[doi.org] Post-inflammatory hyperpigmentation after acne can be as troublesome as the acne itself.[ncbi.nlm.nih.gov] Our aim was to conduct a hybrid systematic review of the evidence for benefits and potential harms of oral spironolactone in the management of acne in adult females.[ncbi.nlm.nih.gov]

  • Addison's Disease

    Loop diuretics may be used, but not aldosterone antagonists such as spironolactone or eplerenone.[ncbi.nlm.nih.gov] KEYWORDS: Addison's disease; active tuberculosis; adrenal insufficiency; freckles; hyperpigmentation; pulmonary tuberculosis[ncbi.nlm.nih.gov] Nature-Throid, Westhroid) somatropin (Genotropin, Genotropin Miniquick, Humatrope) (Genotropin, Genotropin Miniquick, Humatrope and more) nafarelin nasal (Synarel) (Synarel) spironolactone[emedicinehealth.com]

  • Adrenal Insufficiency

    Spironolactone is a diuretic that is used in rare cases. This medication is prohibited at all times in sport.[asada.gov.au] PATIENT AND METHODS: The patient was born with hyperpigmentation, micropenis, penoscrotal hypospadias, and mild cryptorchidism.[ncbi.nlm.nih.gov] This situation may be associated with symptoms suggestive of chronic adrenal insufficiency such as hyperpigmentation, salt craving, and association with autoimmune diseases[ncbi.nlm.nih.gov]

  • Porphyria

    Chloramphenicol Clindamycin Erythromycin Ketoconazole Nitrofurantoin Rifampin Ritonavir Sulfonamides Trimethoprim Heart drugs Hydralazine Lidocaine Methyldopa Nifedipine Spironolactone[msdmanuals.com] Symptoms are: blisters on areas of the skin exposed to the sun such as the face, arms, and hands followed by crusting and scarring; hyperpigmentation; increased hair growth[publichealth.va.gov] Phenazon, Metamizol) Rifampicin Spironolacton Sulfonamide Sultiam Tetracycline Theophyllin u.[prima-eg.de]

  • Acute Hepatic Porphyria

    Chloramphenicol Clindamycin Erythromycin Ketoconazole Nitrofurantoin Rifampin Ritonavir Sulfonamides Trimethoprim Heart drugs Hydralazine Lidocaine Methyldopa Nifedipine Spironolactone[merckmanuals.com] Secondary infections can cause areas of hypo- or hyperpigmentation or sclerodermatous changes and may result in the development of alopecia at sites of repeated skin damage[mayomedicallaboratories.com] […] manifestations Increased fragility of sun-exposed skin blistering and impaired healing ( blistering photosensitivity ) Healing results in scarring and milia formation Hypertrichosis Hyperpigmentation[amboss.com]

  • Becker Nevus Syndrome

    The use of spironolactone, which has anti-androgenic effects in the human body, has been found to improve the breast size in one such patient.[news-medical.net] Abstract The new term Becker nevus syndrome is proposed for a phenotype characterized by the presence of a particular type of organoid epithelial nevus showing hyperpigmentation[ncbi.nlm.nih.gov] Laser treatment (Q-switched ruby, Erbium:YAG) has been used with mixed long-term results. 3 Spironolactone has been used for the management of breast hypoplasia. 2,3 Examination[consultant360.com]

  • Eczema

    […] typically erythematous, edematous, papular, and crusting; followed often by lichenification and scaling and occasionally by duskiness of the erythema and, infrequently, hyperpigmentation[medical-dictionary.thefreedictionary.com] The affected area may appear lighter (hypopigmentation) or darker (hyperpigmentation). These colour changes tend to slowly improve with time.[healthywa.wa.gov.au] Lesions resolve to leave postinflammatory hypopigmentation and hyperpigmentation . What are the complications of DH and coeliac disease?[web.archive.org]

  • Xeroderma Pigmentosum

    Masanobu Ueda, Kenkyo Matsuura, Hidehiko Kawai, Mitsuo Wakasugi and Tsukasa Matsunaga , Spironolactone‐induced XPB degradation depends on CDK7 kinase and SCFFBXL18 E3 ligase[doi.org] Besides the basal cell carcinomas, the background hyperpigmentation and keratotic papules also cleared, and the skin texture improved.[ncbi.nlm.nih.gov] On general examination, there was patchy hyperpigmentation of the exposed areas of skin suggestive of XP.[ncbi.nlm.nih.gov]

  • Cushing's Disease

    High protein intake, and potassium administration (or potassium-sparing drugs such as spironolactone ) Adrenal inhibitors such as metyrapone, mitotane, or ketoconazole Surgery[merckmanuals.com] The disease manifests with signs of CS (truncal and facial obesity and signs of hypercatabolism) as well as skin hyperpigmentation and/or neurological complications in some[orpha.net] Hyperpigmentation of the skin may occur due to the fact that circulating ACTH has some melanocyte stimulating hormone (MSH) like activity.[symptoma.com]

  • Acute Intermittent Porphyria

    Chloramphenicol Clindamycin Erythromycin Ketoconazole Nitrofurantoin Rifampin Ritonavir Sulfonamides Trimethoprim Heart drugs Hydralazine Lidocaine Methyldopa Nifedipine Spironolactone[merckmanuals.com]

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