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133 Possible Causes for Hyperpigmentation, Thick Facial Skin, Weight Gain

  • Corticotroph Pituitary Adenoma

    Over the ensuing years, the patient developed Nelson's syndrome with hyperpigmentation and markedly elevated ACTH levels.[] It is part of a group of diseases that cause Cushing’s syndrome, characterized by signs and symptoms that may include weight gain around the trunk and in the face, stretch[] If the tumor develops after puberty, then the person has the following symptoms of acromegaly: thick, oily skin; coarse features with thick lips and a broad nose; prominent[]

  • Acromegaly

    […] eyelids Increased body hair ( hypertrichosis ), excessive sweating ( hyperhidrosis ), and oily skin ( seborrhoea ) Increased number of skin tags and darkening of the skin ( hyperpigmentation[] We report the case of a 43 years old patient initially diagnosed with acromegaly accompanied by weight gain and acral enlargement.[] The facial aspect is characteristic and includes a widened and thickened nose, prominent cheekbones, forehead bulges, thick lips and marked facial lines.[]

  • Adenoma

    […] cardiomegaly, heat intolerance, weight gain ACTH ( 20%) Cushing's disease : central obesity (moon facies, buffalo hump), thin skin with striae, hirsutism Nelson's syndrome : hyperpigmentation[] PATIENT CONCERNS: A 5-month-old female infant with a history of overeating, hirsutism, and excessive weight gain for the previous 2 months was referred to the hospital.[] The features of acromegaly include characteristic coarsening of facial features (thick lips, exaggerated nasolabial folds, prominent supraorbital ridges, jaw enlargement),[]

  • Hypothyroidism

    Alopecia, sometimes associated with hyperpigmentation, often starts over points of wear. Occasionally, secondary pyoderma (which may produce pruritus) is observed.[] Symptoms include weight gain, constipation, dry skin, and sensitivity to the cold.[] […] expression, dementia or frank psychosis (myxedema madness) Dermatologic manifestations: Facial puffiness; myxedema; sparse, coarse and dry hair; coarse, dry, scaly and thick[]

  • Erythropoietic Protoporphyria

    Chronic UV (ultraviolet) exposure can lead to lichenification, postinflammatory hyperpigmentation, and scarring, particularly over the knuckles and on the nose [ 13, 23 ].[] Credit: Wikimedia Commons Harlequin ichthyosis is a severe genetic disorder that results in thick skin spotted with deep cracks.[] After repetitive exposure, patients may present with lichenification, hypopigmentation, hyperpigmentation and scarring of the skin.EPP usually first presents in childhood,[]

  • Xeroderma Pigmentosum

    Besides the basal cell carcinomas, the background hyperpigmentation and keratotic papules also cleared, and the skin texture improved.[] All Alb-Xpg mice displayed normal growth and weight gain, and none of them died prematurely ( Figure 5A ).[] […] that may be thick, crusty, or scaly) XP patients do not have a common facial appearance, with the exception of XP-CS patients.[]

  • Achard Thiers Syndrome

    Complication due to anti-diabetic treatment was observed in 5 (1.66%) cases in form of photosensitivity (Sulfonylurea-induced), lipodystrophy and hyperpigmentation (with insulin[] Pregnancy causes weight gain and increases levels of estogen and placental hormones, which antagonize insulin. some medications such as thiazide diuretics, adrenal corticosteroids[] The hair itself is sometimes not particularly thick, but the roots are very large which cause a noticeable shadow under the skin.[]

  • Pituitary Gland Carcinoma

    […] complex [ edit ] Carney complex (CNC), also known as LAMB syndrome [20] and NAME syndrome [20] is an autosomal dominant condition comprising myxomas of the heart and skin, hyperpigmentation[] Too much of this hormone causes weight gain, particularly in the body’s trunk.[] If the tumor develops after puberty, then the person has the following symptoms of acromegaly: thick, oily skin; coarse features with thick lips and a broad nose; prominent[]

  • Actinic Lichen Planus

    ) Group 5: Localised hyperpigmentation of the face (eg periorbital hyperpigmentation, naevus of Ota) Group 6: Hyperpigmentation of the neck (eg poikiloderma of Civatte, acanthosis[] If you experience any of these symptoms call your doctor immediately: hives rash itching difficulty swallowing hoarseness unexplained weight gain shortness of breath or difficulty[] Labial skin and mucosa share histological characteristics identical respectively to facial skin and oral mucosa.[]

  • Woodhouse Sakati Syndrome

    Some may present with hyperpigmentation , due to co-secretion with melanocyte-stimulating hormone (MSH), and possible penile enlargement.[] […] patches of thick, darker, velvety skin .[] Signs and symptoms of PCOS include irregular or no menstrual periods , heavy periods , excess body and facial hair , acne , pelvic pain, difficulty getting pregnant , and[]

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