Hyperpigmented Patches: Causes & Reasons

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Possible Causes for Hyperpigmented Patches

Mycosis Fungoides

An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy. [ncbi.nlm.nih.gov]

D, Large asymptomatic hyperpigmented patch with numerous overlying comedones on the left chest. [pediatrics.aappublications.org]

patches on the trunk and right leg with progression over this half a year. [ncbi.nlm.nih.gov]

Vitiligo

[…] that may be surrounded by a hyperpigmented border Vitiligo causes white patches on your skin. [icd9data.com]

Usually progressive, chronic pigmentary anomaly of the skin manifested by depigmented white patches that may be surrounded by a hyperpigmented border. [icd10data.com]

Differential diagnosis includes postinflammatory hypopigmentation, piebaldism (a rare autosomal dominant disorder in which depigmented patches surrounded by hyperpigmented [merckmanuals.com]

Kaposi Sarcoma

Patch-stage Kaposi sarcoma, manifesting as hyperpigmented patches on the thigh. Figure 4. Violaceous and hyperpigmented patches of Kaposi sarcoma. Figure 5. [infectiousdiseaseadvisor.com]

These include: Lichenoid tissue reactions: lichen planus and lichenoid-type drug eruptions can present with hyperpigmented to violaceous patches, papules, or plaques on the [infectiousdiseaseadvisor.com]

(Figure 1, Figure 2), patches (Figure 3, Figure 4, Figure 5), and/or plaques. [infectiousdiseaseadvisor.com]

Dyskeratosis Congenita

Upon initial presentation to clinic at age seven-years-old, the patient was noted to have scattered reticulate hyperpigmented patches on the trunk and anterior lower extremities [ijcasereportsandimages.com]

The predominant cutaneous finding is hypopigmented or hyperpigmented atrophic macules and patches with telangiectasia in a mottled or reticular pattern over sun-exposed and [ibimapublishing.com]

Neurofibromatosis

It is characterized clinically by cutaneous and subcutaneous tumors with patches of hyperpigmentation. [icd9data.com]

The hyperpigmented skin areas, are present from birth and found anywhere on the body surface. They can vary markedly in size and color. [icd9data.com]

Xeroderma Pigmentosum

[…] spots 0001034 Hypopigmented skin patches Patchy loss of skin color 0001053 Keratitis Corneal inflammation 0000491 Melanoma 0002861 Papilloma 0012740 Sensorineural hearing [rarediseases.info.nih.gov]

Cryptorchidism Undescended testes Undescended testis [ more ] 0000028 Dermal atrophy Skin degeneration 0004334 Erythema 0010783 Hyperkeratosis 0000962 Hypermelanotic macule Hyperpigmented [rarediseases.info.nih.gov]

McCune-Albright Syndrome

Cutaneous examination at age 11 years demonstrated a small café au lait patch on the right lateral chest ( Figure 1 A) and hyperpigmented macules on the lower lip ( Figure [jamanetwork.com]

Dermatologic examination revealed a medium-sized café au lait patch on the left temple and the left sacrum and a smaller patch on the right lower abdomen. [jamanetwork.com]

Several hyperpigmented macules were present on bilateral buccal mucosae and vermilion lips, which had developed at age 7 years ( Figure 2 B). [jamanetwork.com]

Actinic Keratosis

Actinic keratosis Other names Solar keratosis, senile keratosis (SK) Actinic keratosis seen on the back of the hands Specialty Dermatology Actinic keratosis (AK), sometimes called solar keratosis or senile keratosis,[1][2] is a pre-cancerous[3] area of thick, scaly, or crusty skin.[4][5] The term actinic keratosis[…] [en.wikipedia.org]

Contact Dermatitis

BACKGROUND: Recently, many cases of acrylate-associated allergic contact dermatitis have appeared among nail salon workers. Common acrylate-containing products in nail salons include traditional nail polish, ultraviolet-cured shellac nail polish, ultraviolet-cured gel nails, and press-on acrylic nails. METHODS: Nail salon[…] [ncbi.nlm.nih.gov]

Non-Hodgkin Lymphoma

Homepage Rare diseases Search Search for a rare disease Non-Hodgkin lymphoma Disease definition Non-Hodgkin malignant lymphomas(NHL) is a heterogeneous group of malignant tumors of the lymphoid system. ORPHA:547 Synonym(s): NHL Prevalence: 1-5 / 10 000 Inheritance: - Age of onset: Adult ICD-10: - OMIM: 605027[…] [orpha.net]

Linear Atrophoderma of Moulin

It is generally characterized by oval or round atrophic, nonsclerotic, hyperpigmented patches following Blaschko's lines. [ncbi.nlm.nih.gov]

Skin biopsy was repeated from normal skin ( Fig 2, A ) and from the hyperpigmented patch ( Fig 2, B ) on the right arm. [ncbi.nlm.nih.gov]

Skin biopsy was repeated from normal skin (Fig 2, A) and from the hyperpigmented patch (Fig 2, B) on the right arm. [mafiadoc.com]

Kwashiorkor

The following symptomatology is evident in acute or chronic phase of Kwashiorkor: General appearance: Kwashiorkor patients show apathy and lethargy as acute signs. They may appear with signs of easy irritability which are all attributed to low energy levels due to lack of protein. They are generally thin with[…] [symptoma.com]

Winchester Syndrome

Phenotypic heterogeneity of cutaneous features are also reported to date of diffusely thickened leathery skin, hypertrichosis, patches of hyperpigmented, hypertrichotic leathery [ncbi.nlm.nih.gov]

2016-11-28T07:07:36+00:00 ORTHOPAEDICS An autosomal recessive disorder (OMIM:259600) characterised by generalised osteolysis and osteopenia, coarse face, corneal opacities, patches [newmedicalterms.com]

An autosomal recessive syndrome (OMIM:259600) characterised by generalised osteolysis and osteopenia, coarse face, corneal opacities, patches of thickened, hyperpigmented [medical-dictionary.thefreedictionary.com]

Arsenical Keratosis

A frequent dermatologic sign of chronic arsenic exposure is cutaneous melanosis of the trunk, which is characterized by hyperpigmented patches often affecting the nipples [ncbi.nlm.nih.gov]

Within these hyperpigmented patches are often seen small areas of hypopigmentation, resembling “raindrops in the dust.” Diffuse alopecia of the scalp may be present. [dermaamin.com]

Diffuse hyperpigmented patches in the intertriginous, genital, and acral areas may be an early sign of chronic arsenic toxicity. [emedicine.medscape.com]

Segmental Odontomaxillary Dysplasia

Case Report A 14-year-old adolescent boy presented to the dermatology clinic at our institution for evaluation of a hyperpigmented hairy patch on the right side of the face [mdedge.com]

We report a 16-month-old black boy with a hyperpigmented patch on his right shoulder and upper pectoral area that extended down his arm. [scinapse.io]

patch over the groin area. [e-ijd.org]

Dyschromatosis Universalis Hereditaria Type 1

The patient′s parents noticed hypopigmented and hyperpigmented patches initially over both hands, followed by involvement of foot and face since around the age of one year [bioline.org.br]

Figure 1: An 8-year old girl with dyschchromatosis universalis hereditica; face shows freckels, tiny hypopigemented macule 1 mm in diameter within hyperpigmented patches, [clinical-pediatrics-dermatology.imedpub.com]

[…] and hyperpigmented/hypopigmented macules. [selfdecode.com]

Tinea Versicolor

Tinea versicolor is a common cutaneous fungal infection, which results in hypopigmented or hyperpigmented patches on the skin. [symptoma.com]

patches associated with erythema, scaling, and itching. [doi.org]

[…] macules, patches, and scaly papules on the chest, neck, and back[, that is caused by Malassezia furfur]. 2, record 1, English, - pityriasis%20versicolor Record number: 1, [btb.termiumplus.gc.ca]

Piebaldism

There were multiple hyperpigmented macules overlying both the depigmented patches and the adjacent normally pigmented skin. [mdedge.com]

[…] surrounds the white unpigmented patches Sometimes islands of normal or hyperpigmented skin occur within the white patches The condition is present at birth and usually remains [dermnetnz.org]

[…] absence of pigmentation) of the central portion of the forehead Eyebrow and eyelash hair may also be affected, either continuously or discontinuously with the forelock White patches [dermnetnz.org]

Familial Primary Localized Cutaneous Amyloidosis

Hyperpigmented patches with superficial erosion in a 12-year-old girl. [plasticsurgerykey.com]

patches of grayish-brown macules with a rippled pattern, [8] associated with deposition of amyloid material in the papillary dermis. [9] The sites most commonly involved [e-ijd.org]

[…] or hypopigmented patches on the upper part of the body, erythema dyschromicum (hyperyperpigmented [brown-gray-blue] on the upper part of the body with a resolving eythematous [infectiousdiseaseadvisor.com]

Acromelanosis

Symptoms INHERITANCE: Autosomal dominant SKIN, NAILS, HAIR: [Skin]; Familial progressive hyperpigmentation and hypopigmentation; Hyperpigmented skin patches (face, neck, trunk [findzebra.com]

Eventually large areas of skin became hyperpigmented. A mother had 2 affected children by different husbands. [findzebra.com]

patches increased in size and number with age MOLECULAR BASIS: Caused by mutation in the KIT ligand gene (KITLG, 184745.0003) [findzebra.com]

Juvenile Nevus

There are only 12 reports of Spitz naevi arising on hyperpigmented patches: 2-12 we describe here three further cases, all on the arms of children, seen in our department [onlinelibrary.wiley.com]

Agminate Spitz nevi arising on hyperpigmented patches. Clin Exp Dermatol. 1994; 19(6):483-486. 9. Akasaka T, Imamura Y, Kon S. [sochiderm.org]

PMID 19561450 Agminate Spitz naevi arising on hyperpigmented patches. Herd RM, Allan SM, Biddlestone L, Buxton PK, Mclaran KM. Clin Exp Dermatol. 1994 Nov;19(6):483-6. [atlasgeneticsoncology.org]

Mesoaxial Synostotic Syndactyly with Phalangeal Reduction

Skin graft can be observed as hyperpigmented patches within web space. Some parts of full-thickness skin graft also were noted to be hair-bearing. [emedicine.medscape.com]

Fixed Eruption

patches as a result of systemic exposure to a drug. [jcsjournal.org]

The healing process occurs spontaneously after few days to weeks after the offending drug is discontinued and may leave a hyperpigmented patch. [ijhas.in]

Lesions may persist from days to weeks and then fade slowly to residual oval hyperpigmented patches. [emedicine.medscape.com]

Pityriasis Rotunda

The dermatoscopic findings were well demarcated, hyperpigmented with brownish patches with polygonal scales. [onlinelibrary.wiley.com]

Hyperpigmented patches on the trunk of a Nigerian woman. Pityriasis rotunda (PR). [actasdermo.org]

Hyperpigmented patches on the trunk of a Nigerian woman. Pityriasis rotunda (PR). Arch Dermatol 2008;144:1509-14. [Figure 1] [ijpd.in]

Angioma

Discover here our latest campaign (2019) Prevent Your skin type Skin type describes how your skin reacts to the sun upon first exposure: Does it burn or does it tan? The skin type is indentified by various characteristics, such as hair colour or fairness of complexion. Discover all skin types Learn Who is at risk[…] [euromelanoma.org]

Warsaw Breakage Syndrome

Mutations in the gene encoding the iron-sulfur-containing DNA helicase DDX11 (ChlR1) were recently identified as a cause of a new recessive cohesinopathy, Warsaw breakage syndrome (WABS), in a single patient with severe microcephaly, pre- and postnatal growth retardation, and abnormal skin pigmentation. Here, using[…] [ncbi.nlm.nih.gov]

Congenital Smooth Muscle Hamartoma

Hyperpigmented patch on the trunk of a neonate. [ijdvl.com]

Lesions are more evident on the older girl (left side), who also showed a hairy slightly-hyperpigmented patch in the lumbar area. [escholarship.org]

patch on the trunk of a neonate. [malacards.org]

Familial Progressive Hyper- and Hypopigmentation

patches in the skin, present in early infancy and increasing in size and number with age. [malacards.org]

Format Definition A disorder characterized by hyperpigmented patches in the skin, present in early infancy and increasing in size and number with age. [uniprot.org]

Familial progressive hyperpigmentation (FPH) is an autosomal dominant genodermatosis characterized by hyperpigmented patches that increase in size and number with age. [bioportfolio.com]

Erythema ab Igne

Physical examination Figure 1 There were reticulated, interlacing, hyperpigmented patches with a few, scattered, erythematous macules at junctions on the medial aspects of [escholarship.org]

On examination, the patient had lace-like hyperpigmented patches on the lower abdomen and upper thighs (Figure 2 ). [cureus.com]

Dermatological examination revealed multiple hyperpigmented reticulated patches with scaling in few areas over the anterior abdominal wall [Figure 1]. [jpbsonline.org]

Yemenite Deaf Blind Hypopigmentation Syndrome

The Yemenite deaf-blind hypopigmentation syndrome was first observed in a Yemenite sister and brother showing cutaneous hypopigmented and hyperpigmented spots and patches, [ncbi.nlm.nih.gov]

The two patients showed cutaneous hypopigmented and hyperpigmented spots and patches on the trunk and extremities, grey hairs, white brows and lashes, micro-cornea, coloboma [doi.org]

[…] spots and patches, microcornea, coloboma and severe hearing loss. [doi.org]