Hyperpigmented Patches: Causes & Reasons

Possible Causes for Hyperpigmented Patches

An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy. [ncbi.nlm.nih.gov]

D, Large asymptomatic hyperpigmented patch with numerous overlying comedones on the left chest. [pediatrics.aappublications.org]

patches on the trunk and right leg with progression over this half a year. [ncbi.nlm.nih.gov]

Vitiligo

[…] that may be surrounded by a hyperpigmented border Vitiligo causes white patches on your skin. [icd9data.com]

Usually progressive, chronic pigmentary anomaly of the skin manifested by depigmented white patches that may be surrounded by a hyperpigmented border. [icd10data.com]

[…] by hyperpigmented areas occur most often on the forehead, neck, anterior trunk, and mid-extremities), morphea (localized scleroderma, in which skin is usually sclerotic), [msdmanuals.com]

Contact Dermatitis

Signs and symptoms of contact dermatitis vary widely and may include: An itchy rash Leathery patches that are darker than usual (hyperpigmented), typically on brown or Black [mayoclinic.org]

Kaposi Sarcoma

Patch-stage Kaposi sarcoma, manifesting as hyperpigmented patches on the thigh. Figure 4. Violaceous and hyperpigmented patches of Kaposi sarcoma. Figure 5. [infectiousdiseaseadvisor.com]

These include: Lichenoid tissue reactions: lichen planus and lichenoid-type drug eruptions can present with hyperpigmented to violaceous patches, papules, or plaques on the [infectiousdiseaseadvisor.com]

(Figure 1, Figure 2), patches (Figure 3, Figure 4, Figure 5), and/or plaques. [infectiousdiseaseadvisor.com]

Dyskeratosis Congenita

Upon initial presentation to clinic at age seven-years-old, the patient was noted to have scattered reticulate hyperpigmented patches on the trunk and anterior lower extremities [ijcasereportsandimages.com]

The predominant cutaneous finding is hypopigmented or hyperpigmented atrophic macules and patches with telangiectasia in a mottled or reticular pattern over sun-exposed and [ibimapublishing.com]

Neurofibromatosis

It is characterized clinically by cutaneous and subcutaneous tumors with patches of hyperpigmentation. [icd9data.com]

The hyperpigmented skin areas, are present from birth and found anywhere on the body surface. They can vary markedly in size and color. [icd9data.com]

Xeroderma Pigmentosum

[…] spots 0001034 Hypopigmented skin patches Patchy loss of skin color 0001053 Keratitis Corneal inflammation 0000491 Melanoma 0002861 Papilloma 0012740 Sensorineural hearing [rarediseases.info.nih.gov]

Cryptorchidism Undescended testes Undescended testis [ more ] 0000028 Dermal atrophy Skin degeneration 0004334 Erythema 0010783 Hyperkeratosis 0000962 Hypermelanotic macule Hyperpigmented [rarediseases.info.nih.gov]

McCune-Albright Syndrome

Cutaneous examination at age 11 years demonstrated a small café au lait patch on the right lateral chest (Figure 1A) and hyperpigmented macules on the lower lip (Figure 1B [jamanetwork.com]

Dermatologic examination revealed a medium-sized café au lait patch on the left temple and the left sacrum and a smaller patch on the right lower abdomen. [jamanetwork.com]

Several hyperpigmented macules were present on bilateral buccal mucosae and vermilion lips, which had developed at age 7 years (Figure 2B). [jamanetwork.com]

Actinic Keratosis

Actinic keratosis Other names Solar keratosis, senile keratosis (SK) Actinic keratosis seen on the back of the hands Specialty Dermatology Actinic keratosis (AK), sometimes called solar keratosis or senile keratosis,[1][2] is a pre-cancerous[3] area of thick, scaly, or crusty skin.[4][5] The term actinic keratosis[…] [en.wikipedia.org]

Non-Hodgkin Lymphoma

Homepage Rare diseases Search Search for a rare disease Non-Hodgkin lymphoma Disease definition Non-Hodgkin malignant lymphomas(NHL) is a heterogeneous group of malignant tumors of the lymphoid system. ORPHA:547 Synonym(s): NHL Prevalence: 1-5 / 10 000 Inheritance: - Age of onset: Adult ICD-10: - OMIM: 605027[…] [orpha.net]

Linear Atrophoderma of Moulin

Skin biopsy was repeated from normal skin (Fig 2, A) and from the hyperpigmented patch (Fig 2, B) on the right arm. [ncbi.nlm.nih.gov]

It is generally characterized by oval or round atrophic, nonsclerotic, hyperpigmented patches following Blaschko's lines. [ncbi.nlm.nih.gov]

A, Linear hyperpigmented atrophic patches on the right upper inner arm, right side of the upper chest, right thigh and right leg following Blaschko’s lines. [mafiadoc.com]

Kwashiorkor

Protein energy malnutrition is the most deadly form of malnutrition. It is the primary or associated cause of around half of the nearly 11 million annual deaths among children under five, 30 000 each day.1 The reasons for this tragedy are quite clearly poverty, underdevelopment, and inequality, yet knowing this does[…] [ncbi.nlm.nih.gov]

Arsenical Keratosis

A frequent dermatologic sign of chronic arsenic exposure is cutaneous melanosis of the trunk, which is characterized by hyperpigmented patches often affecting the nipples [ncbi.nlm.nih.gov]

Physical Examination On the chest, axillae, arms, and legs, faint, hyperpigmented patches with superimposed guttate hypopigmentation were noted. [escholarship.org]

Within these hyperpigmented patches are often seen small areas of hypopigmentation, resembling “raindrops in the dust.” Diffuse alopecia of the scalp may be present. [dermaamin.com]

Segmental Odontomaxillary Dysplasia

Case Report A 14-year-old adolescent boy presented to the dermatology clinic at our institution for evaluation of a hyperpigmented hairy patch on the right side of the face [mdedge.com]

We report a 16-month-old black boy with a hyperpigmented patch on his right shoulder and upper pectoral area that extended down his arm. [scinapse.io]

patch over the groin area. [e-ijd.org]

Dyschromatosis Universalis Hereditaria Type 1

The patient′s parents noticed hypopigmented and hyperpigmented patches initially over both hands, followed by involvement of foot and face since around the age of one year [bioline.org.br]

Figure 1: An 8-year old girl with dyschchromatosis universalis hereditica; face shows freckels, tiny hypopigemented macule 1 mm in diameter within hyperpigmented patches, [clinical-pediatrics-dermatology.imedpub.com]

[…] and hyperpigmented/hypopigmented macules. [selfdecode.com]

Zosteriform Lentiginosis

Part of this controversy is related to the natural history of these lesions that often present at birth as hyperpigmented patches and then take several years to reach their [jamanetwork.com]

Click here to view Figure 2 (a-d) Multiple large tan-colored patches with multiple superimposed discrete hyperpigmented macules, distributed in a zosteriform pattern over [pigmentinternational.com]

They are ultimately distinguished by having a background of normal skin, as opposed to the hyperpigmented light brown background patch seen in NS. [clinicaladvisor.com]

Juvenile Nevus

There are only 12 reports of Spitz naevi arising on hyperpigmented patches: 2-12 we describe here three further cases, all on the arms of children, seen in our department [onlinelibrary.wiley.com]

Agminate Spitz nevi arising on hyperpigmented patches. Clin Exp Dermatol. 1994; 19(6):483-486. 9. Akasaka T, Imamura Y, Kon S. [sochiderm.org]

PMID 19561450 Agminate Spitz naevi arising on hyperpigmented patches. Herd RM, Allan SM, Biddlestone L, Buxton PK, Mclaran KM. Clin Exp Dermatol. 1994 Nov;19(6):483-6. [atlasgeneticsoncology.org]

Pigmented Fungiform Tongue Papillae

[…] papillae in a diffuse and symmetrical pattern RP Type 1 [46] Female 12 African Anterial, lateral, and dorsal Multiple hyperpigmented papillae presenting as dark patches RP [mdpi.com]

Hyperkeratotic Plaques on the Palms and Soles A Red-Brown Plaque on the Nape Hyperpigmented Patches on the Tongue of a Young Girl. Arch. Dermatol. 2009;140:1275–1280. [ncbi.nlm.nih.gov]

Hyperkeratotic Plaques on the Palms and Soles A Red-Brown Plaque on the Nape Hyperpigmented Patches on the Tongue of a Young Girl. Arch. Dermatol. 2009, 140, 1275–1280. [mdpi.com]

Pityriasis Rotunda

Hyperpigmented patches on the trunk of a Nigerian woman. [healthpartners.com]

Hyperpigmented patches on the trunk of a Nigerian woman.Pityriasis rotunda (PR) Arch Dermatol. 2008;144:1509–14 Keywords: Disorder of keratinization; ichthyosis; pityriasis [journals.lww.com]

Hyperpigmented patches on the trunk of a Nigerian woman. Pityriasis rotunda (PR). [actasdermo.org]

Asrar-Facharzt-Haque Syndrome

patch Abnormality of the musculoskeletal system Camptodactyly Camptodactyly of finger Elbow flexion contracture Flexion contracture of finger Flexion contracture of toe Joint [ncbi.nlm.nih.gov]

[…] lymphadenopathy Episcleritis Histiocytosis Lymphadenopathy Splenomegaly Abnormality of the integument Facial telangiectasia Hyperpigmentation of the skin Hypertrichotic hyperpigmented [ncbi.nlm.nih.gov]

Carbon Baby Syndrome

This condition is characterized by hyperpigmented patches that are present since birth and that increase in size and number as the infant grows older. [ijdvl.com]

Angioma

Käytettävä termi Hemangioma Tyyppi Topical Descriptor Alakäsitteet Central Nervous System Venous Angioma Hemangioendothelioma Hemangioma, Capillary Hemangioma, Cavernous Kasabach-Merritt Syndrome Sturge-Weber Syndrome Ohjaustermit Angioma Chorioangioma Chorioangiomas Hemangioma, Histiocytoid Hemangioma,[…] [finto.fi]

Becker Nevus Syndrome

Becker nevus can rarely be congenital or present with familial association.1 Typical presentation is a unilateral tan or brown hyperpigmented patch or plaque with irregular [contemporarypediatrics.com]

The condition is classically characterized by a unilateral, hyperpigmented patch with varying degrees of hypertrichosis on a peripubertal individual. [escholarship.org]

Syndactyly of left 4th and 5th toes with left great toe halux valgus deformity Tissue sample was obtained in a punch biopsy from the hyperpigmented patch over the groin area [ncbi.nlm.nih.gov]

Actinic Lichen Planus

The eruption usually appears during spring and summer, and improvement or complete remission takes place during the winter, leaving hyperpigmented patches [3]. [odermatol.com]

The lesions involve sun-exposed areas and are characterized by well-defined nummular patches which have a deeply hyperpigmented centre surrounded by a hypopigmented zone. [odermatol.com]

Warsaw Breakage Syndrome

Mutations in the gene encoding the iron-sulfur-containing DNA helicase DDX11 (ChlR1) were recently identified as a cause of a new recessive cohesinopathy, Warsaw breakage syndrome (WABS), in a single patient with severe microcephaly, pre- and postnatal growth retardation, and abnormal skin pigmentation. Here, using[…] [ncbi.nlm.nih.gov]

Congenital Smooth Muscle Hamartoma

Hyperpigmented patch on the trunk of a neonate. [ijdvl.com]

A Becker’s nevus typically presents around puberty in males as a hyperpigmented, hypertrichotic patch usually located on the shoulder, chest or scapular region. [healio.com]

Archives of Dermatology 131(5): 611; 614, 1995 Hyperpigmented patch on the trunk of a neonate. [eurekamag.com]

Familial Progressive Hyperpigmentation with or without Hypopigmentation

patches in the skin, present in early infancy and increasing in size and number with age. [malacards.org]

Format Definition A disorder characterized by hyperpigmented patches in the skin, present in early infancy and increasing in size and number with age. [uniprot.org]

Familial progressive hyperpigmentation (FPH) is an autosomal dominant genodermatosis characterized by hyperpigmented patches that increase in size and number with age. [bioportfolio.com]

Acrokeratosis Paraneoplastica of Bazex

He also developed dry hyperpigmented patches of skin on his bilateral anterior shins. There was no involvement of his finger or toe nails. [ncbi.nlm.nih.gov]

patches on the anterior shins Nails: Not affected Skin biopsy Hyperkeratosis, horn cysts with focal intracorneal acute inflammation, psoriaform dermatitis Not performed Not [ncbi.nlm.nih.gov]

[…] and focal necrosis of the tip of the right third finger Nails: Raised, brittle yellow, and thickened Figure 3 Skin: Diffuse thickening and scaling of palms and soles Dry hyperpigmented [ncbi.nlm.nih.gov]

Erythema ab Igne

Physical examination Figure 1 There were reticulated, interlacing, hyperpigmented patches with a few, scattered, erythematous macules at junctions on the medial aspects of [escholarship.org]

On examination, the patient had lace-like hyperpigmented patches on the lower abdomen and upper thighs (Figure 2 ). [cureus.com]

Dermatological examination revealed multiple hyperpigmented reticulated patches with scaling in few areas over the anterior abdominal wall [Figure 1]. [jpbsonline.org]

Acquired Colloid Milium

Case #2: A 68-year-old female presented with clinically diagnosed chronic melasma characterized by dark brown hyperpigmented macules coalescing into patches on both cheeks [redalyc.org]