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394 Possible Causes for Hyperpigmented Skin Lesions

  • Malignant Melanoma in Childhood

    Malignant melanoma is a common type of skin cancer. It is usually diagnosed in the elderly patient and rarely encountered in children. Nevertheless, pediatricians should be aware of malignant melanoma in childhood (MMC), a disorder associated with mortality rates of up to 20%. Clinical and histological features have to[…][symptoma.com]

  • Rothmund Thomson Syndrome

    Immunophenotyping of subpopulations of immunocompetent cells in a biopsy of an atrophic hyperpigmented skin lesion revealed sparsity and unusual distribution of epidermal[ncbi.nlm.nih.gov] Figure 1: Hyperpigmented and hypopigmented skin lesions on patient's face and forearm Click here to view Figure 2: (a) Preoperative picture showing right eye lower eyelid[ijo.in]

  • Acral Lentiginous Melanoma

    BACKGROUND: Acral lentiginous melanoma (ALM) is a rare melanoma subtype that disproportionately afflicts people of colour. ALMs have a worse prognosis than other melanoma subtypes; this has been attributed to aggressive biological behaviour, more advanced stage at presentation and possible disparities in access[…][ncbi.nlm.nih.gov]

  • Linear Atrophoderma of Moulin

    The diagnosis is clinical, characterized by acquired unilateral hyperpigmented, depressed band-like skin lesions following Blaschko's lines.[ncbi.nlm.nih.gov] Observations: Four patients (2 men, 2 women) had a history of unilateral band-like skin lesions located on the lower legs (50%) or the trunk (50%).[karger.com] Physical examination showed atrophic and hyperpigmented skin lesions along Blaschko's lines, which appeared during childhood in 3 cases and at the age of 20 in the last case[ncbi.nlm.nih.gov]

  • Acne Vulgaris

    Topical tretinoin (retinoic acid) therapy for hyperpigmented lesions caused by inflammation of the skin in black patients.[doi.org]

  • Actinic Keratosis

    […] facial lesions and development of an algorithm for automated diagnosis, Skin Research and Technology,, (2019).[doi.org] Peicong Yu, Xiaojie Li, Yi Huang, Hong Liang Tey, Adams Wai Kin Kong, Tomohiro Hakozaki and Ankur Purwar, Inter‐ and intra‐observer agreement in dermatologists’ diagnoses of hyperpigmented[doi.org]

  • Acanthosis Nigricans

    lesions of the skin.[ncbi.nlm.nih.gov] This photograph demonstrates the hyperpigmented, brownish, velvety lesions of acanthosis nigricans.[mountsinai.org] Acanthosis nigricans (AN) is a mucocutaneous disorder that is characterized by focal or diffuse hyperkeratotic, surfaces, which are symmetrically distributed hyperpigmented[ncbi.nlm.nih.gov]

  • Dermatitis

    Chronic eczema can present as lesions that are pruritic, hyperpigmented and/or hypopigmented, well-defined plaques of previously inflamed skin, a scaly appearance and lichenification[podiatrytoday.com] Subacute forms of dermatitis present as less intense pruritic, erythematous, scaling and fissured skin rash.[podiatrytoday.com]

  • Insulin Resistance

    Clinically, these lesions are small, soft, slightly hyperpigmented tumors of variable size and characteristically pedunculated (see Fig. 1 ).[dx.doi.org] These endocrine disturbances alter cellular proliferation, eventually becoming clinically evident as skin tags [ 12 ].[dx.doi.org]

  • Contact Dermatitis

    Chronic eczema can present as lesions that are pruritic, hyperpigmented and/or hypopigmented, well-defined plaques of previously inflamed skin, a scaly appearance and lichenification[podiatrytoday.com] Subacute forms of dermatitis present as less intense pruritic, erythematous, scaling and fissured skin rash.[podiatrytoday.com]

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