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102 Possible Causes for Hyperpigmented Skin Lesions, Small Foot

  • Rothmund Thomson Syndrome

    Immunophenotyping of subpopulations of immunocompetent cells in a biopsy of an atrophic hyperpigmented skin lesion revealed sparsity and unusual distribution of epidermal[] […] eyeball 0000568 Osteoporosis 0000939 Short foot Short feet Small feet [ more ] 0001773 Short nose Decreased length of nose Shortened nose [ more ] 0003196 Short palm 0004279[] Figure 1: Hyperpigmented and hypopigmented skin lesions on patient's face and forearm Click here to view Figure 2: (a) Preoperative picture showing right eye lower eyelid[]

  • Acral Lentiginous Melanoma

    Acrochordon "A small tag of skin that may have a stalk (a peduncle).[] […] responsible for two other genetic diseases, namely, Pfeiffer syndrome (another type of acrocephalosyndactyly) and Crouzon syndrome (purely a craniofacial disorder with no hand or foot[]

  • Tarsal Tunnel Syndrome

    skin lesions and epidermal detachment Brown–Séquard syndrome hemiparaplegia and hyperaesthesia, with ipsilateral loss of stereognosis and contralateral hemianaesthesia; due[] Examination may reveal tinel's sign (radiating pain following nerve percussion) over the tibial nerve at the ankle, weakness and atrophy of the small foot muscles, or loss[] Examination may reveal Tinel's sign (radiating pain following nerve percussion) over the tibial nerve at the ankle, weakness and atrophy of the small foot muscles, or loss[]

  • Linear Atrophoderma of Moulin

    The diagnosis is clinical, characterized by acquired unilateral hyperpigmented, depressed band-like skin lesions following Blaschko's lines.[] A small lesion near the nail for several months.[] Observations: Four patients (2 men, 2 women) had a history of unilateral band-like skin lesions located on the lower legs (50%) or the trunk (50%).[]

  • Dermatitis

    Chronic eczema can present as lesions that are pruritic, hyperpigmented and/or hypopigmented, well-defined plaques of previously inflamed skin, a scaly appearance and lichenification[] Symptoms, including redness, itchiness and small blisters, usually occur within 24 hours of exposure to the irritant.[] This refers to small coin-like areas of eczema scattered over the body.[]

  • Pityriasis Circinata

    Lesions are usually darker than surrounding skin ( hyperpigmented ) in patients with dark skin and lighter ( hypopigmented ) in patients with light skin.[] […] to medium-sized blisters, usually affecting the inner aspect of the foot ( vesiculobullous type).[] These authors reported a mother and son with large hernias, positional foot deformities, thoracic deformity, asthma, and eczematoid dermatitis.[]

  • Winchester Syndrome

    Hyperpigmented erythematous lesions Subcutaneous nodules (interphalangeal joints, knees, feet, elbows, pretibial)[] Small joints of the hands and feet are the most obvious sites of involvement.[] […] osteolysis Fusiform finger swelling Interphalangeal joint erosions Osteoporosis Pes planus Show images Tarsal osteolysis Thin metacarpal cortices Thin metatarsal cortices Skin[]

  • Klinefelter Syndrome

    Incontinentia pigmenti (IP) is a rare X-linked dominant disorder, in which skin lesions distributed along Blaschko's lines appear shortly after birth.[] They are short in stature, averaging 4 foot 7 inches as adults, and often have distinctive webbed necks (i.e., extra folds of skin), small jaws, and high arched palates.[] Early lesions which are erythematous/bullous evolve over time into warty lesions, hyperpigmented swirls/macules, and atrophic hypopigmented streaks.[]

  • Vitiligo

    During the course of the disease, hyperpigmented lesional borders may sometimes be observed, especially in dark-skinned individuals after UV exposure.[] Development and evaluation of ultra-small nanostructured lipid carriers: novel topical delivery system for athlete’s foot. Drug. Deliv. Transl.[] Transient erythema in depigmented skin may be observed following ultraviolet (UV) irradiation, which can be misleading in a clinical context.[]

  • Basal Cell Carcinoma

    Pigmented basal cell carcinoma is a rare subtype and has been described in the literature as a nodular and hyperpigmented lesion; rarely, it can appear as an extensive pigmented[] It tends to be a smooth, elevated, small nodule found on the back, extremities, groin, or sole of the foot.[] Basal cell carcinoma is the most common form of skin cancer, especially in elderly people.[]

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