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55 Possible Causes for Hyperpigmented Skin Lesions, Sparse Eyelashes

  • Rothmund Thomson Syndrome

    Immunophenotyping of subpopulations of immunocompetent cells in a biopsy of an atrophic hyperpigmented skin lesion revealed sparsity and unusual distribution of epidermal[] The authors describe two siblings with RTS and inflammatory conjunctival disease featuring fornix shortening and symblepharon as well as palpebral disease with sparse eyelashes[] Figure 1: Hyperpigmented and hypopigmented skin lesions on patient's face and forearm Click here to view Figure 2: (a) Preoperative picture showing right eye lower eyelid[]

  • Odonto-Onycho-Dermal Dysplasia

    On the affected (left) side, there was skewed inactivation in DNA extracted from an atrophic hyperpigmented lesion of the left arm (87:13 ratio) and borderline random inactivation[] Oligodontia Absent papillae of the tongue Partial alopecia-male pattern Sparse eyelashes/eyebrows ? Sparse axillary/pubic hair ? ? ? ?[] […] scalp hair, sparse eyelashes or sparse eyebrows [ 16 ].[]

  • Noonan Syndrome-Like Disorder with Juvenile Myelomonocytic Leukemia

    skin lesions, cryptorchidism, cardiopathy, neurological lesions, developmental delay, postnatal growth retardation, and autoimmune phenomena.[] These features may include sparse eyebrows and eyelashes, and follicular hyperkeratosis (white bumps on the skin).[] […] eyebrows and eyelashes Developmental and/or cognitive delays Tumor risks While cancer is not a major feature of Noonan syndrome, people with Noonan syndrome are at a slightly[]

  • Autosomal Recessive Nail Dysplasia

    skin lesions and epidermal detachment Brown-Séquard syndrome hemiparaplegia and hyperaesthesia, with ipsilateral loss of stereognosis and contralateral hemianaesthesia; due[] Other skin changes can include: Early hair greying or hair loss Sparse eyelashes Nail ridging Hyperhidrosis (excessive sweating) Squamous cell carcinomas (SCC), often arising[] Sparse or absent eyebrows Sparse or absent eyelashes Diagnosing Fried Syndrome A physician can diagnose Fried syndrome on the basis of physical features.[]

  • Bloch Sulzberger Syndrome

    […] verrucous skin lesions.[] Hair changes include vertex alopecia and sparse eyebrows and eyelashes.[] Sparse eyelashes and eyebrows are also reported. Teeth.[]

  • Skin Atrophy

    Firstly, we suspected of BILP in patients who presented with unilateral and specific configuration (except head and neck) of lichenoid, hyperpigmented or atrophic skin lesions[] Eyelashes and/or eyebrows may be sparse.[] The eyebrows may be hypoplastic and the eyelashes likewise are sparse. The lid fissures often slant down and telecanthus has been noted.[]

  • Ectrodactyly

    In racially pigmented skin, the lesions may be hypo or hyperpigmented.[] , thick or thin, unruly hair Sparse pubic hair Sparse axillary hair (underarm) Sparse eyebrows Sparse eyelashes Nails Pitted nails (ice pick-like depressions in the nails)[] There was sparse hair on the body and scalp and no hair on the back of the hands. Upper and lower eyelids of both sides showed sparse eyelashes.[]

  • HAIR-AN Syndrome

    […] are velvety, hyperpigmented patches of skin that occur with HAIR-AN syndrome after long-term exposure of the keratinocytes to insulin.[] Underdeveloped Thick, discolored Hair Fine, brittle, slow-growing Total balding (alopecia) Missing in spots for males Sparse eyelashes Sparse eyebrow Absent underarm hair[] Sparse or absent eyebrows Sparse or absent eyelashes Diagnosing Fried Syndrome A physician can diagnose Fried syndrome on the basis of physical features.[]

  • Absent Thumb - Short Stature - Immunodeficiency Syndrome

    […] or hypopigmented lesions respectively.[] eyelashes Short ribs Accelerated skeletal maturation Rhizomelia Bowing of the long bones Sparse and thin eyebrow Abnormality of retinal pigmentation Fine hair Abnormally[] […] hair, eyelashes, and, or eyebrows, small stature and predisposition to skin cancer and osteosarcoma are some key features of this syndrome. {2,3} Other features in individual[]

  • Legius Syndrome

    Many other hyperpigmented skin lesions are commonly misdiagnosed as CAL, such as the lesion in Figure 2D. Figure 2.[] The hair is typically sparse, curly, fine or thick, woolly or brittle; eyelashes and eyebrows may be absent or sparse. Nails may be dystrophic or fast growing.[] lesions intermingled with scattered depigmentation, depigmented patches of skin and hair, respectively (as presented in Fig. 3 ).[]

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