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479 Possible Causes for Hyperreflexia, Pediatric Disorder, Spasticity - Hyperreflexia

  • Hallervorden-Spatz Syndrome

    Described features include 9,11 : progressive dementia extrapyramidal signs (rigidity, dystonia, choreoathetosis) corticospinal signs (spasticity, hyperreflexia) dysarthria[radiopaedia.org] Neurologically, opisthotonus, rigidity of extremities, dystonia, hyperreflexia, profound emaciation, and bilaterally positive Babinski signs were present.[ncbi.nlm.nih.gov] […] treatments and interventions Covers neurological, neuropsychiatric, and neuromedical disorders across the lifespan (pediatric, adult, and geriatric populations) Includes[books.google.com]

  • Globoid Cell Leukodystrophy

    Spasticity. Hyperreflexia. Clonus. Pyramidal paresis of limb or limbs. Extensor plantar responses. Unsteadiness of gait. Psychomotor retardation. Dysphagia. Deafness.[patient.info] , Pediatric Clinics of North America, 62, 3, (787), (2015).[doi.org] Neurodegenerative disorders of childhood. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics. 20th ed.[nlm.nih.gov]

  • Canavan Disease

    After that, hypotonia progresses to spasticity, hyperreflexia, extensor plantar responses, and tonic extensor spasms. The extensor spasms may occur in response to noise.[ncbi.nlm.nih.gov] Clinical manifestation is being noted for diagnosing such as presentation of joint stiffness and hyperreflexia including as well the presence of optic atrophy.[healthool.com] Disease Focus: Genetic Disorder Neurological Disorders Pediatrics Grant Application Details Application Title: Developing a therapeutic candidate for Canavan disease using[cirm.ca.gov]

  • Friedreich Ataxia

    His examination was significant for spastic gait, hyperreflexia, and sensory neuropathy. Genetic testing revealed a compound heterozygous mutation in the FXN gene.[ncbi.nlm.nih.gov] We report two patients with delayed-onset, hyperreflexia and gradually progressive disease.[ncbi.nlm.nih.gov] Leigh syndrome (subacute necrotizing encephalomyopathy) is a rare, highly morbid and fatal pediatric disorder that results in severe neurological and neuromuscular dysfunction[bioelectron.com]

  • Lesch Nyhan Syndrome

    In LNS patients there are three major signs of pyramidal dysfunction: spasticity, hyperreflexia and the extensor plantar reflex (also known as the Babinski reflex: the great[themedicalbiochemistrypage.org] It is typically characterized by choreoathetosis, hypertonia, hyperreflexia, and self-mutilation.[ncbi.nlm.nih.gov] This finding suggests an involvement of the toxicity of the Z-riboside in the pathogenesis of neurological disorders in Lesch-Nyhan syndrome and possibly in other pediatric[ncbi.nlm.nih.gov]

  • Renpenning Syndrome

    Proud: microcephaly, ACC, spasticity, seizures, ataxia, genital anomalies.[pediatrics.aappublications.org] […] atrophy ; Cleft palate ; Clinodactyly of the 5th finger ; Coloboma ; Cupped ear ; Decreased testicular size ; Epicanthus ; Hearing impairment ; High palate ; Hypermetropia ; Hyperreflexia[mousephenotype.org] One typical immune reaction in infants and children is PANDAS, or Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infection, another disorder[wikivisually.com]

  • Infantile Neuroaxonal Dystrophy

    Clinical Onset before age three years Psychomotor regression (most common presenting feature) Early truncal hypotonia followed by spastic tetraparesis (usually with hyperreflexia[ncbi.nlm.nih.gov] […] weakness 0003324 Gliosis 0002171 Global developmental delay 0001263 Hearing impairment Deafness Hearing defect [ more ] 0000365 Hyperactivity More active than typical 0000752 Hyperreflexia[rarediseases.info.nih.gov] This book provides an update on pediatric neurological disorders with cerebellar involvement.[books.google.com]

  • Autosomal Dominant Spastic Paraplegia Type 10

    ) is a rare type of hereditary spastic paraplegia that can present as either a pure form of spastic paraplegia with lower limb spasticity, hyperreflexia and extensor plantar[orpha.net] He graduated from Western Reserve University School of Medicine, did his pediatric training in Chicago and Cleveland, and his pediatric neurology residency at the Johns Hopkins[books.google.com] […] paraplegia type 10 Disease definition A rare type of hereditary spastic paraplegia that can present as either a pure form of spastic paraplegia with lower limb spasticity, hyperreflexia[orpha.net]

  • Autosomal Recessive Spastic Paraplegia Type 46

    Affiliated tissues include brain , and related phenotypes are nystagmus and hyperreflexia Disease Ontology : 12 A hereditary spastic paraplegia that has material basis in[malacards.org] Albert Einstein College of Medicine · Pediatric Neurology and Developmental Disorders-Tanjala Gipson and Deepa Menon, Kennedy Krieger Institute and Johns Hopkins University[books.google.com] The gait is spastic with weakness, hyperreflexia, and extensor plantar responses in the lower limbs. The upper limbs are variably involved and movements are dysmetric.[disorders.eyes.arizona.edu]

  • Autosomal Dominant Spastic Paraplegia Type 8

    24, Autosomal Recessive Symptoms via clinical synopsis from OMIM: 57 Neurologic Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes[malacards.org] People with this condition may also have hyperreflexia, decreased ability to feel vibrations, muscular atrophy and decreased bladder control.[ivami.com] Albert Einstein College of Medicine · Pediatric Neurology and Developmental Disorders-Tanjala Gipson and Deepa Menon, Kennedy Krieger Institute and Johns Hopkins University[books.google.com]

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