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80 Possible Causes for Hyperreflexia, Proximal Weakness of the Lower Extremities, Spasticity - Hyperreflexia

  • Autosomal Dominant Spastic Paraplegia Type 31

    24, Autosomal Recessive Symptoms via clinical synopsis from OMIM: 57 Neurologic Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes[malacards.org] weakness of the lower extremities with spastic gait and brisk reflexes, with a bimodal age of onset of either childhood or adulthood ( 30 years).[orpha.net] Neurologic examination revealed hyperreflexia and spasticity in the lower extremities, weakness of hip flexion and ankle dorsiflexion, extensor plantar response, diminished[neurology.org]

  • Autosomal Dominant Spastic Paraplegia Type 8

    24, Autosomal Recessive Symptoms via clinical synopsis from OMIM: 57 Neurologic Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes[malacards.org] Limb weakness is usually affecting proximal, muscles more than distal musculature.[neuroweb.us] People with this condition may also have hyperreflexia, decreased ability to feel vibrations, muscular atrophy and decreased bladder control.[ivami.com]

  • Myelopathy

    Physical examination commonly elicits long tract signs such as spasticity, hyperreflexia, and abnormal reflexes such as Babinski or Hoffman's sign.[neurosurgery.ucla.edu] This is characterized by atrophy of the thenar and hypothenar eminence, stereoanesthesia, the ‘useless hand syndrome’, and proximal lower extremity weakness.[nature.com] Clinical hyperreflexia was tested at the MCP joint, using a six-axis load cell.[ncbi.nlm.nih.gov]

  • Cervical Myelopathy

    […] gait," hesitant and jerky) Myelopathic or "upper motor neuron" findings such as spasticity, hyperreflexia, clonus, Babinski, and Hoffman signs, and bowel and bladder dysfunction[emoryhealthcare.org] This is characterized by atrophy of the thenar and hypothenar eminence, stereoanesthesia, the ‘useless hand syndrome’, and proximal lower extremity weakness.[nature.com] BACKGROUND: Gait dysfunction associated with spasticity and hyperreflexia is a primary symptom in patients with compression of cervical spinal cord.[ncbi.nlm.nih.gov]

  • Amyotrophic Lateral Sclerosis Type 1

    hyperreflexia ( ) Hoffman's ( ) Babinski's spastic dysarthria lower motor neuron (LMN) signs muscular atrophy weakness clinical fasciculations clumsiness Evaluation Diagnosis[orthobullets.com] Patterns of weakness & dysfunction: Common features 40 Limb weakness Early patterns Asymmetric May involve proximal or distal musculature Specific patterns Upper Lower extremity[neuromuscular.wustl.edu] Clinical manifestations include progressive weakness, atrophy, fasciculation, hyperreflexia, dysarthria, dysphagia, and eventual paralysis of respiratory function.[icd10data.com]

  • Autosomal Recessive Spastic Paraplegia Type 18

    There is gross spasticity, hyperreflexia and extensor plantar response. In severe cases, the child is unable to sit unsupported and is certainly unable to walk.[patient.info] weakness, spasticity.[1pdf.net] People with this condition can also experience exaggerated reflexes (hyperreflexia), a decreased ability to feel vibrations, muscle wasting (amyotrophy), and reduced bladder[ghr.nlm.nih.gov]

  • Autosomal Recessive Spastic Paraplegia Type 7

    , hyperreflexia, lower-limb weakness and decreased vibration sensation 37 yrs, 22 – 60 yrs AD Uncomplicated KIAA0196 (SPG8) DNA Sequencing 25 – 42 yrs AR Uncomplicated/ Paraplegin[1pdf.net] People with this form of spastic paraplegia may also have hyperreflexia in the arms, dysarthria, dysphagia, nystagmus, mild hearing loss, scoliosis, foot arch elevation, sensory[ivami.com] People with this condition can also experience exaggerated reflexes (hyperreflexia), ankle spasms, high-arched feet (pes cavus), and reduced bladder control.[icdlist.com]

  • Autosomal Dominant Spastic Paraplegia Type 41

    […] by onset in adolescence or early adulthood of slowly progressive spastic paraplegia, proximal muscle weakness of the lower extremities and small hand muscles, hyperreflexia[orpha.net] Affiliated tissues include globus pallidus, skin and bone, and related phenotypes are babinski sign and lower limb hyperreflexia Disease Ontology : 12 A hereditary spastic[malacards.org] There was hyperreflexia in both upper and lower limbs and spastic paraplegia with a bilateral Babinski sign.[journals.plos.org]

  • Autosomal Recessive Spastic Paraplegia Type 28

    , hyperreflexia, lower-limb weakness and decreased vibration sensation 37 yrs, 22 – 60 yrs AD Uncomplicated KIAA0196 (SPG8) DNA Sequencing 25 – 42 yrs AR Uncomplicated/ Paraplegin[1pdf.net] People with this condition can also experience exaggerated reflexes (hyperreflexia), ankle spasms, high-arched feet (pes cavus), and reduced bladder control.[ghr.nlm.nih.gov] […] most notable at the iliopsoas, tibialis anterior, hamstring muscles  difficulty in walking, decreased vibratory sense at the ankles, and paresthesia  In lower extremities hyperreflexia[slideshare.net]

  • Multifocal Motor Neuropathy

    Upper motor neuron signs (spasticity, hyperreflexia, extensor plantar response).[clinicaltrials.gov] Some patients develop progressive asymmetric lower motor syndromes with predominant early weakness in proximal musculature ( P-LMN syndromes ).[neuromuscular.wustl.edu] Atrophy may be present, but hyperreflexia and spasticity are not seen.[ncbi.nlm.nih.gov]

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