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87 Possible Causes for Hyperreninemia, Hypokalemia, Hypotension

  • Gitelman Syndrome

    In these children, a tendency towards hypokalemia was first noted during the third week of life.[ncbi.nlm.nih.gov] This paper presents 3 sisters with Gitelman syndrome who could not tolerate magnesium supplements, and whose hypotension and polyuria were eliminated by taking 2 mg/kg/day[ncbi.nlm.nih.gov] Clinical history was positive for symptoms of orthostatic hypotension and polyuria. There was no history of drugs consumption other than potassium supplements.[ncbi.nlm.nih.gov]

  • Bartter Syndrome

    Hypokalemia was corrected only on addition of spironolactone on day 11.[sjkdt.org] Lab Metabolic alkalosis, decreased serum K , increased urine K , increased renin, increased aldosterone.[medical-dictionary.thefreedictionary.com] Bartter syndrome is characterized by hyperplasia of the juxtaglomerular cells along with: hypokalemia metabolic alkalosis hypotension/normotension elevated plasma renin elevate[radiopaedia.org]

  • Metabolic Alkalosis

    Hypokalemia seen with heat stress is secondary to sweat as well as renal potassium wasting.[ncbi.nlm.nih.gov] Three patients with hypokalemia, normal blood pressure, metabolic alkalosis, hyperreninemia and hyperaldosteronism are described.[ncbi.nlm.nih.gov] We describe a case of medication induced metabolic alkalosis in a maintenance dialysis patient who developed severe hypotension while undergoing a lactate hemofiltration procedure[ncbi.nlm.nih.gov]

  • Renal Salt-Wasting Syndrome

    In 3 patients, fludrocortisone treatment was complicated by hypokalemia, and in 1 patient by hypertension, which necessitated a dose reduction or brief cessation of therapy[pediatrics.aappublications.org] The proximal site of salt transport defect has been suggested by the absence of hyperreninemia and hypokalemia, which would be a distinguishing feature of Bartter’s syndrome[karger.com] Seven of seventy patients treated with cisplatin over 18 months developed salt-wasting nephropathy and orthostatic hypotension.[annals.org]

  • Bartter's Disease

    Laboratory testing is significant for hypokalemia, hypochloremia, and metabolic alkalosis.[medbullets.com] Lab Metabolic alkalosis, decreased serum K , increased urine K , increased renin, increased aldosterone.[medical-dictionary.thefreedictionary.com] Bartter syndrome is characterized by hyperplasia of the juxtaglomerular cells along with: hypokalemia metabolic alkalosis hypotension or normotension elevated plasma renin[radiopaedia.org]

  • Hyponatremia

    Carbamazepine was discontinued, fluid restriction ordered, and hypokalemia was corrected.[ncbi.nlm.nih.gov] In this setting, release of both antidiuretic hormone (ADH) (increases renal permeability to water) and renin (increases renal sodium retention) occurs.[doi.org] After several weeks of suffering from gastroenteritis with vomiting, she presented with disturbance of consciousness, hypotension, dehydration, and severe hyponatremia (108[ncbi.nlm.nih.gov]

  • Hypoaldosteronism

    A 51-year-old Japanese woman with hypokalemia due to distal renal tubular acidosis associated with Sjögren's syndrome exhibited a decreased plasma aldosterone level despite[ncbi.nlm.nih.gov] These results suggest adrenal insensitivity to angiotensin II, possibly a defect in adrenal angiotensin II receptors, as the cause of hypoldosteronism with hyperreninemia[ncbi.nlm.nih.gov] It can also cause urinary sodium wasting, leading to volume depletion and hypotension.[en.wikipedia.org]

  • Hypokalemia

    MayoClinic.com: Low potassium (hypokalemia) MedicineNet.com: Low Potassium (Hypokalemia) eMedicineHealth.com: Low Potassium (Hypokalemia) Content of Selected Foods per Common[en.wikipedia.org] Intravenous fluid boluses of normal saline (10.5 L in about 24 h) and vasopressors were started with rapid correction of hypotension.[ncbi.nlm.nih.gov] […] rhythyms Constipation Fatigue Muscle Damage Muscle Weakness or spasms Paralysis [2] Nausea and vomiting Polyuria, nocturia or polydipsia Altered mental status Signs of Ileus Hypotension[physio-pedia.com]

  • 18-Hydroxylase Deficiency

    Two sisters with amenorrhea, hypokalemia, hypertension, and cystic ovaries. [ ] 17.[moldiag.com] Decreased circulating aldosterone level ; Dehydration ; Episodic fever ; Failure to thrive ; Feeding difficulties in infancy ; Growth delay ; Hyperkalemia ; Hyponatremia ; Hypotension[mousephenotype.org] She was referred to nephrology due to hypertension, hypokalemia, and mild proteinuria.[journals.plos.org]

  • Diabetes Insipidus

    An adult male with metastatic medullary thyroid cancer presented with hyperglycemia, hypernatremia, hypokalemia, hypertension, acne-like rash, and diabetes insipidus (urine[ncbi.nlm.nih.gov] […] ingress from the renal filtrate - up to 12% of glomerular filtrate may be reabsorbed cardiovascular effects (V2): tachycardia, facial flushing, hypotension, increased plasma renin[aic.cuhk.edu.hk] We report vasopressin (AVP) responses to hypotension in nine patients with ADI and nine controls.[ncbi.nlm.nih.gov]

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