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33 Possible Causes for Hyperreninemia, Hypokalemia, Muscle Hypotonia

  • Bartter Syndrome

    Hypokalemia was corrected only on addition of spironolactone on day 11.[sjkdt.org] Lab Metabolic alkalosis, decreased serum K , increased urine K , increased renin, increased aldosterone.[medical-dictionary.thefreedictionary.com] […] tone (hypotonia), muscle spasms, growth delays and a failure to grow and gain weight as would be expected based on age and gender (failure to thrive).[rarediseases.org]

  • Gitelman Syndrome

    In these children, a tendency towards hypokalemia was first noted during the third week of life.[ncbi.nlm.nih.gov] […] tone (hypotonia), muscle spasms, growth delays and a failure to grow and gain weight as would be expected based on age and gender (failure to thrive).[rarediseases.org] Both probands show hypokalemia, hypochloraemia, hypocalcinuria, hyperreninemia, and hyperaldosteronemia; Proband A has normal serum magnesium and increased urinary sodium[ncbi.nlm.nih.gov]

  • Hyponatremia

    Carbamazepine was discontinued, fluid restriction ordered, and hypokalemia was corrected.[ncbi.nlm.nih.gov] In this setting, release of both antidiuretic hormone (ADH) (increases renal permeability to water) and renin (increases renal sodium retention) occurs.[doi.org] He had severe hypokalemia with hypertension and was diagnosed with pseudoaldosteronism.[ncbi.nlm.nih.gov]

  • Conn Syndrome

    Hypernatremia, hypervolemia and hypokalemia are common.[symptoma.com] When renin increases (due to low blood pressure, decreased blood flow to the kidneys or to a sodium deficiency), aldosterone increases; when renin decreases, aldosterone decreases.In[labtestsonline.org.au] Condition similar to Conn's syndrome may be caused by kidneys that can produce an excessive amount of renin.[health-tutor.com]

  • Hypokalemia

    MayoClinic.com: Low potassium (hypokalemia) MedicineNet.com: Low Potassium (Hypokalemia) eMedicineHealth.com: Low Potassium (Hypokalemia) Content of Selected Foods per Common[en.wikipedia.org] […] manifestations: -Hypotonia and muscle weakness -Respiratory depression -Muscle cramps -Constipation and/or ileus -Rhabdomyolysis and myoglobinuria In hyperkalemia, the resting[clinicaladvisor.com] However, in more severe cases, patients can present with muscle weakness, paraesthesia, constipation / ileus or pseudo-obstruction, hypotonia, hyporeflexia, muscle cramps,[teachmesurgery.com]

  • EAST Syndrome

    Disease definition SeSAME syndrome is characterized by seizures, sensorineural deafness, ataxia, intellectual deficit, and electrolyte imbalance (hypokalemia, metabolic alkalosis[orpha.net] Clinical presentation of the patients was homogeneous and included premature birth attributable to polyhydramnios, severe renal salt loss, normotensive hyperreninemia, hypokalemic[pediatrics.aappublications.org] Low or weak muscle tone 0001252 Polydipsia Extreme thirst 0001959 Polyuria Increased urine output 0000103 Renal potassium wasting 0000128 Renal salt wasting Loss of salt[rarediseases.info.nih.gov]

  • Proximal Renal Tubular Acidosis

    Hypokalemia may be associated with it; occasionally leading to features like hypokalemic periodic paralysis.[ncbi.nlm.nih.gov] Amniocentesis : chloride levels in amniotic fluid Laboratory diagnostics Hypokalemi a and m etabolic alkalosis Hypercalciuria Hyperuricemia ( 50% of cases) Hyperreninemia[amboss.com] The patient developed hypotonia and blepharoptosis and exhibited growth retardation.[ncbi.nlm.nih.gov]

  • Distal Renal Tubular Acidosis

    The South East Asian cases are associated with more severe hypokalemia.[en.wikipedia.org] Amniocentesis : chloride levels in amniotic fluid Laboratory diagnostics Hypokalemi a and m etabolic alkalosis Hypercalciuria Hyperuricemia ( 50% of cases) Hyperreninemia[amboss.com] Examination of the central nervous system revealed hypotonia with grade 3 power, proximally and distally, in all four limbs. No neck muscle weakness was present.[mjdrdypu.org]

  • Non-Infective Neonatal Diarrhea

    We report a case of CLD complicated with recurrent episodes of ileus, metabolic alkalosis, and hypokalemia causing frequent hospitalization in a 4-year-old boy.[ncbi.nlm.nih.gov] During indomethacin treatment, no clinical improvement could be achieved whereas hyperreninemia and hyperaldosteronism improved.[ncbi.nlm.nih.gov] […] and muscle wasting. 90% of patients had maternal hypertension and 75% of patients had absence of normal meconium at birth.[unboundmedicine.com]

  • Fanconi Renotubular Syndrome

    Progressive hypokalemia and renal dysfunction were observed since 2006 and the patient was admitted to our department in 2009 for further management of hypokalemia (serum[ncbi.nlm.nih.gov] The renal phenotype characterized by hypokalemia, hypomagnesemia, hyperreninemia, hyperaldosteronism and nephrocalcinosis, resembling Bartter syndrome, was diagnosed when[jmedicalcasereports.biomedcentral.com] […] in endocytic trafficking and actin skeleton dynamics. [2] Lowe syndrome involves eyes (congenital cataracts, glaucoma with buphthalmos, corneal keloid), nervous system (muscle[ijaweb.org]

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