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34 Possible Causes for Hyperreninemia, Hypokalemia, Urine Chloride Increased

  • Bartter's Disease

    Laboratory testing is significant for hypokalemia, hypochloremia, and metabolic alkalosis.[medbullets.com] They lose excess amounts of salt (sodium chloride) in their urine, which leads to dehydration, constipation, and increased urine production (polyuria).[ghr.nlm.nih.gov] Lab Metabolic alkalosis, decreased serum K , increased urine K , increased renin, increased aldosterone.[medical-dictionary.thefreedictionary.com]

  • Bartter Syndrome

    Hypokalemia was corrected only on addition of spironolactone on day 11.[sjkdt.org] They lose excess amounts of salt (sodium chloride) in their urine, which leads to dehydration, constipation, and increased urine production (polyuria).[ghr.nlm.nih.gov] Lab Metabolic alkalosis, decreased serum K , increased urine K , increased renin, increased aldosterone.[medical-dictionary.thefreedictionary.com]

  • Gitelman Syndrome

    In these children, a tendency towards hypokalemia was first noted during the third week of life.[ncbi.nlm.nih.gov] ) Bartter's syndrome (inherited defect in TALH, increased urine chloride)[medlibes.com] Both probands show hypokalemia, hypochloraemia, hypocalcinuria, hyperreninemia, and hyperaldosteronemia; Proband A has normal serum magnesium and increased urinary sodium[ncbi.nlm.nih.gov]

  • Antenatal Bartter Syndrome

    Hypokalemia and alkalosis with hypertension: Hyperaldosterism Monogenetic forms of hypertension Renal artery stenosis Cushing syndrome Hypokalemia and alkalosis with normal[cancertherapyadvisor.com] They lose excess amounts of salt (sodium chloride) in their urine, which leads to dehydration, constipation, and increased urine production (polyuria).[ghr.nlm.nih.gov] Rofecoxib suppressed hyperreninemia to a similar extent as indomethacin.[ncbi.nlm.nih.gov]

  • Conn Syndrome

    Hypernatremia, hypervolemia and hypokalemia are common.[symptoma.com] When renin increases (due to low blood pressure, decreased blood flow to the kidneys or to a sodium deficiency), aldosterone increases; when renin decreases, aldosterone decreases.In[labtestsonline.org.au] Condition similar to Conn's syndrome may be caused by kidneys that can produce an excessive amount of renin.[health-tutor.com]

  • Liddle Syndrome

    His serum renin was Discussion: The evaluation of hypokalemia begins with whether or not the hypokalemia is transient (due to cell shift) or sustained from either renal or[utswim.wordpress.com] Hyperactive renin-angiotensin system (plasma renin increased, lack of effect of angiotensin on blood pressure, renal potassium wasting, increased renal prostaglandin production[patient.info] All patients had hypokalemia and suppressed plasma renin activity.[ncbi.nlm.nih.gov]

  • Cerebral Salt-Wasting Syndrome

    The proximal site of salt transport defect has been suggested by the absence of hyperreninemia and hypokalemia, which would be a distinguishing feature of Bartter's syndrome[ncbi.nlm.nih.gov] Generally, it is known to be helpful diagnosing SIADH when the patient exhibits urinary sodium and chloride excretion increased more than 30 mmol/L and fractional excretions[frontiersin.org] The most common adverse effect associated with fludrocortisone was hypokalemia, which was observed in up to 73% of patients. 15 The length of therapy depends on the clinical[thepermanentejournal.org]

  • Metabolic Alkalosis

    Hypokalemia seen with heat stress is secondary to sweat as well as renal potassium wasting.[ncbi.nlm.nih.gov] Urine pH: Increased, higher than 7.0.[nurseslabs.com] Three patients with hypokalemia, normal blood pressure, metabolic alkalosis, hyperreninemia and hyperaldosteronism are described.[ncbi.nlm.nih.gov]

  • Renal Salt-Wasting Syndrome

    In 3 patients, fludrocortisone treatment was complicated by hypokalemia, and in 1 patient by hypertension, which necessitated a dose reduction or brief cessation of therapy[pediatrics.aappublications.org] Generally, it is known to be helpful diagnosing SIADH when the patient exhibits urinary sodium and chloride excretion increased more than 30 mmol/L and fractional excretions[frontiersin.org] The proximal site of salt transport defect has been suggested by the absence of hyperreninemia and hypokalemia, which would be a distinguishing feature of Bartter’s syndrome[karger.com]

  • Renal Tubular Acidosis

    Subsequently, type 1 RTA due to Sjögren's syndrome was unveiled by sustained hypokalemia (3.3 to 3.4 mEq/L), persistent alkaline urine pH ( 6.0) despite metabolic acidosis[ncbi.nlm.nih.gov] In distal RTA, due to a lack of H in tubular lumen, bicarbonate is lost in urine, which results in increased chloride absorption causing hyperchloremia.[lecturio.com] Both effects cause hypotension with consequent hyperreninemia and hyperaldosteronism, which aggravates potassium wasting.[jpma.org.pk]

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