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23 Possible Causes for Hyperreninemia, Hyporeflexia, Muscle Weakness

  • Hyponatremia

    A 52-year-old Sri Lankan man presented with anorexia, nausea, fatigue, generalized muscle weakness, and cramps for 1 week.[ncbi.nlm.nih.gov] In this setting, release of both antidiuretic hormone (ADH) (increases renal permeability to water) and renin (increases renal sodium retention) occurs.[doi.org] Other symptoms include: Fatigue Convulsions Headache Muscle weakness or spasms Nausea and vomiting Restlessness Confusion Decreased consciousness Treatment of Hyponatremia[sportsinjuryclinic.net]

  • Hypokalemia

    Neurological examination showed a lower extremity muscle weakness with three-fifths muscular strength of the quadriceps and tibialis anterior muscle on both sides.[ncbi.nlm.nih.gov] […] resulting hyperpolarization leads to a reduced neuromuscular excitability and thus causes: Muscular adynamia (extreme form: paresis ) Weakening or suspension of reflexes (hyporeflexia[flexikon.doccheck.com] With more severe hypokalemia, flaccid paralysis and hyporeflexia may result.[en.wikipedia.org]

  • Schwartz-Jampel Syndrome

    554 Case 89A A Woman with Muscle Weakness and a Skin Rash 559 Case 90 A Man with Muscle Pains 567 Case 91 An Older Woman with Progressive Muscle Weakness 572 Case 92 An HIVInfected[books.google.com] Lab Metabolic alkalosis, decreased serum K , increased urine K , increased renin, increased aldosterone.[medical-dictionary.thefreedictionary.com] He had proximal muscle hypertrophy, distal muscle wasting and generalized hyporeflexia. Bone X-ray revealed pseudofracture of humerus.[advbiores.net]

  • Conn Syndrome

    Low potassium may cause fatigue, muscle cramps, muscle weakness, numbness, or temporary paralysis.[endocrinediseases.org] When renin increases (due to low blood pressure, decreased blood flow to the kidneys or to a sodium deficiency), aldosterone increases; when renin decreases, aldosterone decreases.In[labtestsonline.org.au] Condition similar to Conn's syndrome may be caused by kidneys that can produce an excessive amount of renin.[health-tutor.com]

  • Bartter Syndrome

    Clinical findings Proximal muscle weakness, failure to thrive, short stature, convulsions, tetany, cramps, ileus, gout, mental retardation, enuresis, nocturia, polyuria, salt[medical-dictionary.thefreedictionary.com] Gitelman syndrome are characterized by fluid, electrolyte, urinary, and hormonal abnormalities, including renal potassium, sodium, chloride, and hydrogen wasting; hypokalemia; hyperreninemia[msdmanuals.com] Low blood levels of potassium can cause muscle weakness, cramping, and fatigue.[webmd.com]

  • Hypokalemic Nephropathy

    There is generalized muscle weakness, characterized by ventroflexion of the neck; other signs include weight loss, chronic vomiting and constipation.[medical-dictionary.thefreedictionary.com] Excessive aldosterone production may result from congenital adrenal hyperplasia, glucocorticoid treatment, some genetic defects and hyperreninemia. • Intrinsic renal potassium[symbiosisonlinepublishing.com] […] resulting hyperpolarization leads to a reduced neuromuscular excitability and thus causes: Muscular adynamia (extreme form: paresis ) Weakening or suspension of reflexes (hyporeflexia[flexikon.doccheck.com]

  • Nelson Syndrome

    Symptoms include a round face, thin arms and legs, severe fatigue and muscle weakness, high blood pressure and high blood sugar, purple or pink stretch marks on the skin,[icd10data.com] […] colleagues in 1962, [1] represents a set of closely related, autosomal recessive renal tubular disorders characterized by hypokalemia, hypochloremia, metabolic alkalosis, and hyperreninemia[emedicine.medscape.com] Neurologic examination Hyporeflexia and delayed relaxation time of reflexes are signs that may be present in patients with hypothyroidism.[emedicine.medscape.com]

  • Respiratory Muscle Paralysis

    weakness.[msdmanuals.com] Both effects cause hypotension with consequent hyperreninemia and hyperaldosteronism, which aggravates potassium wasting.[jpma.org.pk] (GBS) is a disorder causing demyelination and axonal degeneration resulting in acute, ascending and progressive neuropathy, characterised by weakness, paraesthesiae and hyporeflexia[patient.info]

  • Hyperaldosteronism

    […] spasms Muscle weakness Numbness Polyuria Polydipsia Tingling Metabolic alkalosis The causes of primary hyperaldosteronism are adrenal hyperplasia and adrenal adenoma (Conn's[en.wikipedia.org] Hyperreninemia and secondary aldosteronism have also been reported in patients with pheochromocytoma, apparently as a result of functional renal artery stenosis.[emedicine.medscape.com] Other signs include myalgia, tremor, muscle cramps, flaccid paralysis and hyporeflexia, which tend to appear in the most severe states of hypokalemia.[symptoma.com]

  • Renal Tubular Acidosis

    We report a case of a 66-year-old diabetic patient who presented with muscle weakness 2 weeks after kidney transplantation.[ncbi.nlm.nih.gov] Both effects cause hypotension with consequent hyperreninemia and hyperaldosteronism, which aggravates potassium wasting.[jpma.org.pk] The signs and symptoms of hypokalemia, such as muscle weakening, hyporeflexia, and paralysis, are evident, especially in the already mentioned Type 1 and Type 2 RTA.[symptoma.com]

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