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40 Possible Causes for Hyperreninemia, Muscle Twitch, Muscle Weakness

  • Bartter's Disease

    Clinical findings Proximal muscle weakness, failure to thrive, short stature, convulsions, tetany, cramps, ileus, gout, mental retardation, enuresis, nocturia, polyuria, salt[medical-dictionary.thefreedictionary.com] Saint-Petersburg, Russia Abstract Abstract Bartter syndrome (BS) tubulopathy with autosomal recessive (AR) type of genetic inheritance, manifested hypokalemia, metabolic alkalosis, hyperreninemia[adc.bmj.com] Low blood levels of potassium can cause muscle weakness, cramping, and fatigue.[webmd.com]

  • Hypokalemia

    Neurological examination showed a lower extremity muscle weakness with three-fifths muscular strength of the quadriceps and tibialis anterior muscle on both sides.[ncbi.nlm.nih.gov] […] deficiency may produce muscular weakness and lead to paralysis and respiratory failure; muscular malfunction may result in hypoventilation, paralytic ileus, hypotension, muscle[icd9data.com] Clinical features include transient periods of muscle weakness and tetany, dizziness, abdominal pains and constipation.[ncbi.nlm.nih.gov]

  • Conn Syndrome

    Low potassium may cause fatigue, muscle cramps, muscle weakness, numbness, or temporary paralysis.[endocrinediseases.org] Pins and needles feeling Eyesight problems Paralysis that comes and goes Muscle twitching and cramps The severity may depend on the degree of the electrolyte abnormality.[urologyhealth.org] When renin increases (due to low blood pressure, decreased blood flow to the kidneys or to a sodium deficiency), aldosterone increases; when renin decreases, aldosterone decreases.In[labtestsonline.org.au]

  • Hyponatremia

    A 52-year-old Sri Lankan man presented with anorexia, nausea, fatigue, generalized muscle weakness, and cramps for 1 week.[ncbi.nlm.nih.gov] As hyponatremia becomes more severe, muscle twitching and seizures may occur.[merckmanuals.com] In this setting, release of both antidiuretic hormone (ADH) (increases renal permeability to water) and renin (increases renal sodium retention) occurs.[doi.org]

  • Metabolic Alkalosis

    In most patients, the symptom of muscle weakness and polyuria occur early in life, which may be attributed to potassium depletion.[ncbi.nlm.nih.gov] Muscle twitching is also called muscle fasciculation. Twitching involves small muscle contractions in the body.[healthline.com] weakness; myalgia; muscle cramps; tremors in the hands; and twitching muscles.[battlediabetes.com]

  • Respiratory Alkalosis

    weakness, depressed central respiratory drive, and resultant alveolar hypoventilation.[ncbi.nlm.nih.gov] Other symptoms of respiratory alkalosis may encompass: agitation seizures dizziness light headedness tingling, numbness irregular heart beats muscle twitching , spasms , weakness[healthblurbs.com] , Cl- expansion Renal loss of H : edematous states (heart failure, cirrhosis, nephrotic syndrome), hyperaldosteronism, hypercortisolism, excess ACTH, exogenous steroids, hyperreninemia[thoracic.org]

  • Respiratory Muscle Paralysis

    weakness.[msdmanuals.com] Both effects cause hypotension with consequent hyperreninemia and hyperaldosteronism, which aggravates potassium wasting.[jpma.org.pk] Nicotine acts on nicotinic receptors in the brain and muscles. According to Elmhurst College, nicotine causes muscle twitching and muscle weakness.[livestrong.com]

  • Addison's Disease

    The physical examination was completely normal except for muscle weakness, hyperpigmentation on labial mucosa and skin in a patient.[ncbi.nlm.nih.gov] twitching or seizures.[innerbody.com] […] concentration after 60 minutes to a peak of 18 mcg/dL Plasma renin : Mineralocorticoid deficiency is confirmed with a relatively low aldosterone level in the setting of hyperreninemia[pedclerk.bsd.uchicago.edu]

  • Hypoaldosteronism

    A 53-year-old man with retinitis pigmentosa, who had two years' complaints of general malaise and muscle weakness, noticed occasional attacks of the cramps of the lower legs[ncbi.nlm.nih.gov] Symptoms can include fatigue, confusion, muscle twitches, weakness, nausea, and a headache Very low blood pressure can cause symptoms such as dizziness, lightheadedness, fainting[healdove.com] These results suggest adrenal insensitivity to angiotensin II, possibly a defect in adrenal angiotensin II receptors, as the cause of hypoldosteronism with hyperreninemia[ncbi.nlm.nih.gov]

  • Alkalosis

    Clinical features include transient periods of muscle weakness and tetany, abdominal pains, and chondrocalcinosis. [ 8 ] Other features include: Short stature.[patient.info] People may have irritability, muscle twitching, muscle cramps, or even muscle spasms. Blood is tested to diagnose alkalosis.[merckmanuals.com] Symptoms of alkalosis can include any of the following: Confusion (can progress to stupor or coma) Hand tremor Lightheadedness Muscle twitching Nausea, vomiting Numbness or[nlm.nih.gov]

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