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66 Possible Causes for Hyperreninemia, Muscle Weakness, Polydipsia

  • Bartter's Disease

    Clinical findings Proximal muscle weakness, failure to thrive, short stature, convulsions, tetany, cramps, ileus, gout, mental retardation, enuresis, nocturia, polyuria, salt[medical-dictionary.thefreedictionary.com] Main manifestations of BS with neonatal age: vomiting, diarrhoea, polyuria, polydipsia, signs of dehydration, with infants: hypocalcemic convulsions, paresis hypokalemic.[adc.bmj.com] […] plasma renin elevate aldosterone antenatal polyhydramnios Classification There are two subtypes of Bartter syndrome: classic: presents in early childhood with polyuria, polydipsia[radiopaedia.org]

  • Gitelman Syndrome

    The clinical spectrum is wide and usually characterized by chronic fatigue, cramps, muscle weakness and paresthesiae.[ncbi.nlm.nih.gov] […] distal convoluted tubule ( DCT ) of the kidneys Kidneys fail to reabsorb sodium, magnesium, chloride, and potassium, causing them to be excreted into the urine History / PE : Polydipsia[medlibes.com] The main features of this syndrome include normal or low blood pressure, hypokalemia, metabolic alkalosis, hypomagnesemia, hypocalciuria, and hyperreninemia.[ncbi.nlm.nih.gov]

  • Hyponatremia

    A 52-year-old Sri Lankan man presented with anorexia, nausea, fatigue, generalized muscle weakness, and cramps for 1 week.[ncbi.nlm.nih.gov] Adult schizophrenics who receive psychostimulants have also been shown to develop polydipsia with hyponatremia.[ncbi.nlm.nih.gov] In this setting, release of both antidiuretic hormone (ADH) (increases renal permeability to water) and renin (increases renal sodium retention) occurs.[doi.org]

  • Hypokalemic Nephropathy

    There is generalized muscle weakness, characterized by ventroflexion of the neck; other signs include weight loss, chronic vomiting and constipation.[medical-dictionary.thefreedictionary.com] Hypokalemia can lead to a renal concentrating defect leading to polyuria and polydipsia- DI 2.[nephronpower.com] Excessive aldosterone production may result from congenital adrenal hyperplasia, glucocorticoid treatment, some genetic defects and hyperreninemia. • Intrinsic renal potassium[symbiosisonlinepublishing.com]

  • Conn Syndrome

    Low potassium may cause fatigue, muscle cramps, muscle weakness, numbness, or temporary paralysis.[endocrinediseases.org] The authors report on a 5-year-old girl who had symptoms of polyuria, polydipsia, and fatigue, and for whom the diagnosis of hyperaldosteronemia was suggested by a low serum[ncbi.nlm.nih.gov] When renin increases (due to low blood pressure, decreased blood flow to the kidneys or to a sodium deficiency), aldosterone increases; when renin decreases, aldosterone decreases.In[labtestsonline.org.au]

  • Bartter Syndrome

    Clinical findings Proximal muscle weakness, failure to thrive, short stature, convulsions, tetany, cramps, ileus, gout, mental retardation, enuresis, nocturia, polyuria, salt[medical-dictionary.thefreedictionary.com] […] plasma renin elevate aldosterone antenatal polyhydramnios Classification There are two subtypes of Bartter syndrome: classic: presents in early childhood with polyuria, polydipsia[radiopaedia.org] After birth, the infant is seen to urinate and drink excessively ( polyuria, and polydipsia, respectively).[en.wikipedia.org]

  • Renal Tubular Acidosis

    A 33-year-old HIV-positive man with Hepatitis C and tuberculous lymphadenitis was admitted due to deep venous thrombosis and generalized muscle weakness.[ncbi.nlm.nih.gov] Clinical Manifestations In children the clinical spectrum is nonspecific including anorexia, failure to thrive, vomiting and dehydration, constipation, polyuria, and polydipsia[renaltube.com] Both effects cause hypotension with consequent hyperreninemia and hyperaldosteronism, which aggravates potassium wasting.[jpma.org.pk]

  • Antenatal Bartter Syndrome

    Low blood levels of potassium can cause muscle weakness, cramping, and fatigue.[webmd.com] […] plasma renin elevate aldosterone antenatal polyhydramnios Classification There are two subtypes of Bartter syndrome: classic: presents in early childhood with polyuria, polydipsia[radiopaedia.org] Rofecoxib suppressed hyperreninemia to a similar extent as indomethacin.[ncbi.nlm.nih.gov]

  • Hypokalemia

    Neurological examination showed a lower extremity muscle weakness with three-fifths muscular strength of the quadriceps and tibialis anterior muscle on both sides.[ncbi.nlm.nih.gov] […] exhibit signs of the following: Abnormal heart rhythyms Constipation Fatigue Muscle Damage Muscle Weakness or spasms Paralysis [2] Nausea and vomiting Polyuria, nocturia or polydipsia[physio-pedia.com] Hypokalemia may also impair the ability of the kidneys to concentrate urine, resulting in excessive urination (polyuria) and excessive thirst (polydipsia).[rarediseases.org]

  • Renal Salt-Wasting Syndrome

    […] wasting [ wāst ing ] 1. the gradual deterioration of an individual, usually with loss of strength and muscle mass; it may be accompanied by loss of appetite, which makes it[medical-dictionary.thefreedictionary.com] […] polyuria, defined as over three liters of urine output over 24 hours in an adult), high amounts of sodium in the urine, low blood sodium concentration, [1] excessive thirst (polydipsia[en.wikipedia.org] The proximal site of salt transport defect has been suggested by the absence of hyperreninemia and hypokalemia, which would be a distinguishing feature of Bartter’s syndrome[karger.com]

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