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79 Possible Causes for Hyperreninemia, Muscle Weakness, Polyuria

  • Bartter's Disease

    Clinical findings Proximal muscle weakness, failure to thrive, short stature, convulsions, tetany, cramps, ileus, gout, mental retardation, enuresis, nocturia, polyuria, salt[medical-dictionary.thefreedictionary.com] Abstract Bartter syndrome is an autosomic recessive disease characterized by severe polyuria and sodium renal loss.[ncbi.nlm.nih.gov] Saint-Petersburg, Russia Abstract Abstract Bartter syndrome (BS) tubulopathy with autosomal recessive (AR) type of genetic inheritance, manifested hypokalemia, metabolic alkalosis, hyperreninemia[adc.bmj.com]

  • Gitelman Syndrome

    The clinical spectrum is wide and usually characterized by chronic fatigue, cramps, muscle weakness and paresthesiae.[ncbi.nlm.nih.gov] We discuss in this article the atypical electrolytes losses found in our patient, as well as the possible mechanisms of severe polyuria.[ncbi.nlm.nih.gov] The main features of this syndrome include normal or low blood pressure, hypokalemia, metabolic alkalosis, hypomagnesemia, hypocalciuria, and hyperreninemia.[ncbi.nlm.nih.gov]

  • Hypokalemic Nephropathy

    There is generalized muscle weakness, characterized by ventroflexion of the neck; other signs include weight loss, chronic vomiting and constipation.[medical-dictionary.thefreedictionary.com] Hypokalemia can lead to a renal concentrating defect leading to polyuria and polydipsia- DI 2.[nephronpower.com] Excessive aldosterone production may result from congenital adrenal hyperplasia, glucocorticoid treatment, some genetic defects and hyperreninemia. • Intrinsic renal potassium[symbiosisonlinepublishing.com]

  • Hypokalemia

    Neurological examination showed a lower extremity muscle weakness with three-fifths muscular strength of the quadriceps and tibialis anterior muscle on both sides.[ncbi.nlm.nih.gov] Last time we reviewed the proposed mechanisms by which hypercalcaemia can induce polyuria.[renalfellow.org] Clinical features include transient periods of muscle weakness and tetany, dizziness, abdominal pains and constipation.[ncbi.nlm.nih.gov]

  • Conn Syndrome

    Low potassium may cause fatigue, muscle cramps, muscle weakness, numbness, or temporary paralysis.[endocrinediseases.org] […] pri·mar·y al·dos·ter·on·ism an adrenocortical disorder caused by excessive secretion of aldosterone and characterized by headaches, nocturia, polyuria, fatigue, hypertension[medical-dictionary.thefreedictionary.com] When renin increases (due to low blood pressure, decreased blood flow to the kidneys or to a sodium deficiency), aldosterone increases; when renin decreases, aldosterone decreases.In[labtestsonline.org.au]

  • Renal Salt-Wasting Syndrome

    […] wasting [ wāst ing ] 1. the gradual deterioration of an individual, usually with loss of strength and muscle mass; it may be accompanied by loss of appetite, which makes it[medical-dictionary.thefreedictionary.com] Other causes of polyuria and hyponatremia should be excluded. Treatment aims at restoring the lost water and salt.[ncbi.nlm.nih.gov] The proximal site of salt transport defect has been suggested by the absence of hyperreninemia and hypokalemia, which would be a distinguishing feature of Bartter’s syndrome[karger.com]

  • Bartter Syndrome

    Clinical findings Proximal muscle weakness, failure to thrive, short stature, convulsions, tetany, cramps, ileus, gout, mental retardation, enuresis, nocturia, polyuria, salt[medical-dictionary.thefreedictionary.com] Abstract Bartter syndrome is an autosomic recessive disease characterized by severe polyuria and sodium renal loss.[ncbi.nlm.nih.gov] Gitelman syndrome are characterized by fluid, electrolyte, urinary, and hormonal abnormalities, including renal potassium, sodium, chloride, and hydrogen wasting; hypokalemia; hyperreninemia[msdmanuals.com]

  • Renal Tubular Acidosis

    A 33-year-old HIV-positive man with Hepatitis C and tuberculous lymphadenitis was admitted due to deep venous thrombosis and generalized muscle weakness.[ncbi.nlm.nih.gov] Despite polyuria, both patients developed resistant hyperkalemia that needed further hemodialysis.[ncbi.nlm.nih.gov] Both effects cause hypotension with consequent hyperreninemia and hyperaldosteronism, which aggravates potassium wasting.[jpma.org.pk]

  • Antenatal Bartter Syndrome

    Low blood levels of potassium can cause muscle weakness, cramping, and fatigue.[webmd.com] This disorder typically presents as a life-threatening condition beginning in utero, with marked fetal polyuria that leads to polyhydramnios and premature delivery.[ncbi.nlm.nih.gov] Rofecoxib suppressed hyperreninemia to a similar extent as indomethacin.[ncbi.nlm.nih.gov]

  • Hyponatremia

    A 52-year-old Sri Lankan man presented with anorexia, nausea, fatigue, generalized muscle weakness, and cramps for 1 week.[ncbi.nlm.nih.gov] Review of symptoms revealed polydipsia and polyuria.[jaoa.org] In this setting, release of both antidiuretic hormone (ADH) (increases renal permeability to water) and renin (increases renal sodium retention) occurs.[doi.org]

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