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149 Possible Causes for Hypersegmented Neutrophils

  • Vitamin B12 Deficiency

    Investigations revealed a hemoglobin of 11.4 gm/dl (MCV-107.4 fl); peripheral blood smear showed hypersegmented neutrophils.[] The blood film showed mild oval macrocytosis, occasional nucleated red cells, and some hypersegmented neutrophils.[]

  • Megaloblastic Anaemia in Pregnancy

    Hypersegmented neutrophils are a clinical laboratory finding where the neutrophils abnormally show six or more lobes.[] […] on other servers : Macro-ovalocytosis Round macrocytes in liver disease Hypersegmented neutrophil Differential diagnosis Critical to distinguish between cobalamin and folate[] Megaloblastic anemia, with macroovalocytes (thin arrows) and hypersegmented neutrophils (thick arrow). Figure 1.[]

  • Megaloblastic Anemia

    RESULTS: Giant neutrophilic series such as giant metamyelocytes and giant band cells were found to have extraordinarily higher DNA ploidy, while hypersegmented neutrophils[] Regardless of the MCV, our megaloblastic patients had hypersegmented neutrophils and elevated MPXI levels without visible alteration of granule content.[] Peripheral blood smear demonstrated hypersegmented neutrophils and megalocytes with emergence of myeloblasts, giant metamyelocytes, and nucleated red cells.[]

  • Vitamin B12 Deficiency Anemia

    Peripheral blood smear showed schistocytosis, anisocytosis, and poikilocytosis with hypersegmented neutrophils.[] Lab abnormalities include a macrocytic anemia with hypersegmented neutrophils and macro ovalocytosis noted on peripheral smear.[] neutrophil Macrocytes, macro-ovalocytes, nucleated RBCs and hypersegmented neutrophils Back to top[]

  • Macrocytic Anemia

    neutrophils, and reticulocytopenia.[] B 12 deficiency - macrocytosis, hypersegmented neutrophils, low plasma vit. B12 level.[] Hypersegmented neutrophils ( 5 lobes) (3-5 is normal) b/c they do not divide enough times Neutrophils with 5 lobes. What is normal number of lobes?[]

  • Boucher-Neuhäuser Syndrome

    All 3 patients with BNS had hypersegmented neutrophils on peripheral-blood films. Our findings indicate that hypersegmented neutrophils are a characteristic of BNS.[] Moreover, we first found hypersegmented neutrophils in two BNS patients with PNPLA6 mutations.[] Hypergonadotropic hypogonadism and hypersegmented neutrophils in a patient with ataxia-telangiectasia-like disorder: potential diagnostic clues? Am. J. Med. Genet.[]

  • Folate-Deficiency Anemia

    You get Macrocytic/Megaloblastic Anemia with Hypersegmented Neutrophils and increased Homocysteine levels.[] neutrophils, macro ovalocytes Advertisement[] Giant bands (right) and hypersegmented polymorphonuclear neutrophils (below) are common. Even megakaryocytes (right) may be hypersegmented.[]

  • Constitutional Megaloblastic Anemia due to Folate Metabolism Disorder

    These hypersegmented neutrophils can be detected in the peripheral blood (using a diagnostic smear of a blood sample).[] Increase in reticulocyte count within the first week Disappearance of hypersegmented neutrophils in 2-3 weeks Anemia of Chronic Disease - cause Chronic infections, – TB,[] […] anemia may be severe, MCV usually markedly elevated; anisocytosis, poikilocytosis, macro-ovalocytosis, hypersegmented neutrophils; retic count reduced; B12 LOW![]

  • Posthemorrhagic Anaemia of the Newborn

    neutrophil Hypochromic anaemia Hypoprothrombinaemia Idiopathic thrombocytopenic purpura Juvenile myelomonocytic leukaemia Kostmann syndrome Laminopathy Leukaemia Leucopoenia[] Vitamin B12 and folate levels to differentiate. 29 Peripheral blood smear showing hypersegmented neutrophils, characteristic of megaloblastic anemia. 30 Treatment of deficiency[] “Do we have any hypersegmented neutrophils or macro-ovalocytes?”[]

  • Refractory Megaloblastic Anemia

    B 12 deficiency - macrocytosis, hypersegmented neutrophils, low plasma vit. B12 level.[] Megaloblastic anemia, with macroovalocytes (thin arrows) and hypersegmented neutrophils (thick arrow). Figure 1.[] . - Neutrophils are larger and have hypersegmented nuclei o When more than 5% of neutrophils have more than 5 lobes or at least one 6 lobed WBC in a film is present it is[]

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