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117 Possible Causes for Hypersegmented Neutrophils

  • Megaloblastic Anemia

    RESULTS: Giant neutrophilic series such as giant metamyelocytes and giant band cells were found to have extraordinarily higher DNA ploidy, while hypersegmented neutrophils[] Regardless of the MCV, our megaloblastic patients had hypersegmented neutrophils and elevated MPXI levels without visible alteration of granule content.[] Peripheral blood smear demonstrated hypersegmented neutrophils and megalocytes with emergence of myeloblasts, giant metamyelocytes, and nucleated red cells.[]

  • Macrocytic Anemia

    neutrophils, and reticulocytopenia.[] B 12 deficiency - macrocytosis, hypersegmented neutrophils, low plasma vit. B12 level .[] Hypersegmented neutrophils ( 5 lobes) (3-5 is normal) b/c they do not divide enough times Neutrophils with 5 lobes. What is normal number of lobes?[]

  • Megaloblastic Anaemia in Pregnancy

    Hypersegmented neutrophils are a clinical laboratory finding where the neutrophils abnormally show six or more lobes.[] […] on other servers : Macro-ovalocytosis Round macrocytes in liver disease Hypersegmented neutrophil Differential diagnosis Critical to distinguish between cobalamin and folate[] Megaloblastic anemia, with macroovalocytes (thin arrows) and hypersegmented neutrophils (thick arrow) . Figure 1.[]

  • Folate-Deficiency Anemia

    You get Macrocytic/Megaloblastic Anemia with Hypersegmented Neutrophils and increased Homocysteine levels.[] neutrophils, macro ovalocytes Advertisement[] Giant bands (right) and hypersegmented polymorphonuclear neutrophils (below) are common. Even megakaryocytes (right) may be hypersegmented.[]

  • Vitamin B12 Deficiency Anemia

    Peripheral blood smear showed schistocytosis, anisocytosis, and poikilocytosis with hypersegmented neutrophils.[] Lab abnormalities include a macrocytic anemia with hypersegmented neutrophils and macro ovalocytosis noted on peripheral smear.[] neutrophil Macrocytes, macro-ovalocytes, nucleated RBCs and hypersegmented neutrophils Advertisement[]

  • Boucher-Neuhauser Syndrome

    Moreover, we first found hypersegmented neutrophils in two BNS patients with PNPLA6 mutations.[] neutrophils: a novel disorder or a new variant of Boucher–Neuhauser syndrome?[] Hypergonadotropic hypogonadism and hypersegmented neutrophils in a patient with ataxia-telangiectasia-like disorder: potential diagnostic clues? Am. J. Med. Genet.[]

  • Constitutional Megaloblastic Anemia due to Folate Metabolism Disorder

    These hypersegmented neutrophils can be detected in the peripheral blood (using a diagnostic smear of a blood sample).[] Increase in reticulocyte count within the first week Disappearance of hypersegmented neutrophils in 2-3 weeks Anemia of Chronic Disease - cause Chronic infections, – TB,[] […] anemia may be severe, MCV usually markedly elevated; anisocytosis, poikilocytosis, macro-ovalocytosis, hypersegmented neutrophils; retic count reduced; B12 LOW![]

  • Pancytopenia

    Hypo / hypersegmented Neutrophil 12.[] Hypersegmented neutrophils were noted in the blood films of 36 (92.3%) patients with megaloblastic anemia.[] In the present study, 49 cases of megaloblastic anemia patients had macrocytic RBCs and hypersegmented neutrophils, which are the diagnostic features.[]

  • Normochromic Anemia

    neutrophils, characteristic of megaloblastic anemia.[] neutrophils LDH is low Indirect bilirubin is low Serum B12 is usually very low.[] These hypersegmented neutrophils can be detected in the peripheral blood (using a diagnostic smear of a blood sample).[]

  • Folic Acid Deficiency

    In this group and a non-hypersegmented-neutrophil control group there was a significant negative correlation between average numbers of neutrophilic lobes and serum folate[] There were 8.2%-9.7% hypersegmented neutrophils in the blood (normal 5%) after BMT both with and without folic acid deficiency.[] Laboratory findings for Folic Acid Deficiency: Hypersegmented Neutrophil American Society of Hematology Megaloblastic Anemia Increased Lactate Dehydrogenase (LDH) Increased[]

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