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117 Possible Causes for Hypersegmented Neutrophils

  • Megaloblastic Anemia

    RESULTS: Giant neutrophilic series such as giant metamyelocytes and giant band cells were found to have extraordinarily higher DNA ploidy, while hypersegmented neutrophils[ncbi.nlm.nih.gov] Regardless of the MCV, our megaloblastic patients had hypersegmented neutrophils and elevated MPXI levels without visible alteration of granule content.[ncbi.nlm.nih.gov] Peripheral blood smear demonstrated hypersegmented neutrophils and megalocytes with emergence of myeloblasts, giant metamyelocytes, and nucleated red cells.[ncbi.nlm.nih.gov]

  • Macrocytic Anemia

    neutrophils, and reticulocytopenia.[msdmanuals.com] B 12 deficiency - macrocytosis, hypersegmented neutrophils, low plasma vit. B12 level .[enotes.tripod.com] Hypersegmented neutrophils ( 5 lobes) (3-5 is normal) b/c they do not divide enough times Neutrophils with 5 lobes. What is normal number of lobes?[brainscape.com]

  • Megaloblastic Anaemia in Pregnancy

    Hypersegmented neutrophils are a clinical laboratory finding where the neutrophils abnormally show six or more lobes.[findatopdoc.com] […] on other servers : Macro-ovalocytosis Round macrocytes in liver disease Hypersegmented neutrophil Differential diagnosis Critical to distinguish between cobalamin and folate[pathologyoutlines.com] Megaloblastic anemia, with macroovalocytes (thin arrows) and hypersegmented neutrophils (thick arrow) . Figure 1.[aafp.org]

  • Folate-Deficiency Anemia

    You get Macrocytic/Megaloblastic Anemia with Hypersegmented Neutrophils and increased Homocysteine levels.[stomponstep1.com] neutrophils, macro ovalocytes Advertisement[pathologyoutlines.com] Giant bands (right) and hypersegmented polymorphonuclear neutrophils (below) are common. Even megakaryocytes (right) may be hypersegmented.[med-ed.virginia.edu]

  • Vitamin B12 Deficiency Anemia

    Peripheral blood smear showed schistocytosis, anisocytosis, and poikilocytosis with hypersegmented neutrophils.[shmabstracts.com] Lab abnormalities include a macrocytic anemia with hypersegmented neutrophils and macro ovalocytosis noted on peripheral smear.[thebigl.co] neutrophil Macrocytes, macro-ovalocytes, nucleated RBCs and hypersegmented neutrophils Advertisement[pathologyoutlines.com]

  • Boucher-Neuhauser Syndrome

    Moreover, we first found hypersegmented neutrophils in two BNS patients with PNPLA6 mutations.[nature.com] neutrophils: a novel disorder or a new variant of Boucher–Neuhauser syndrome?[link.springer.com] Hypergonadotropic hypogonadism and hypersegmented neutrophils in a patient with ataxia-telangiectasia-like disorder: potential diagnostic clues? Am. J. Med. Genet.[nature.com]

  • Constitutional Megaloblastic Anemia due to Folate Metabolism Disorder

    These hypersegmented neutrophils can be detected in the peripheral blood (using a diagnostic smear of a blood sample).[en.wikipedia.org] Increase in reticulocyte count within the first week Disappearance of hypersegmented neutrophils in 2-3 weeks Anemia of Chronic Disease - cause Chronic infections, – TB,[freezingblue.com] […] anemia may be severe, MCV usually markedly elevated; anisocytosis, poikilocytosis, macro-ovalocytosis, hypersegmented neutrophils; retic count reduced; B12 LOW![studystack.com]

  • Pancytopenia

    Hypo / hypersegmented Neutrophil 12.[slideshare.net] Hypersegmented neutrophils were noted in the blood films of 36 (92.3%) patients with megaloblastic anemia.[ayubmed.edu.pk] In the present study, 49 cases of megaloblastic anemia patients had macrocytic RBCs and hypersegmented neutrophils, which are the diagnostic features.[jahjournal.org]

  • Normochromic Anemia

    neutrophils, characteristic of megaloblastic anemia.[medicine.academic.ru] neutrophils LDH is low Indirect bilirubin is low Serum B12 is usually very low.[physicianassistantexamreview.com] These hypersegmented neutrophils can be detected in the peripheral blood (using a diagnostic smear of a blood sample).[en.wikipedia.org]

  • Folic Acid Deficiency

    In this group and a non-hypersegmented-neutrophil control group there was a significant negative correlation between average numbers of neutrophilic lobes and serum folate[ncbi.nlm.nih.gov] There were 8.2%-9.7% hypersegmented neutrophils in the blood (normal 5%) after BMT both with and without folic acid deficiency.[ncbi.nlm.nih.gov] Laboratory findings for Folic Acid Deficiency: Hypersegmented Neutrophil American Society of Hematology Megaloblastic Anemia Increased Lactate Dehydrogenase (LDH) Increased[medical-institution.com]

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