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19 Possible Causes for Hypersegmented Neutrophils, Neonatal Hyperbilirubinemia

  • Microangiopathic Hemolytic Anemia

    In the neonatal period, severe hemolysis and hyperbilirubinemia can leave permanent neurological sequelae.[bioline.org.br] neutrophils M1 Select Answer to see Preferred Response PREFERRED RESPONSE 3 ARTICLES (2) Topic COMMENTS (10) Please login to add comment.[step1.medbullets.com] neutrophils M1 Select Answer to see Preferred Response PREFERRED RESPONSE 3 Sorry, this question is for PEAK Premium Subscribers only ARTICLES (1) Topic COMMENTS (10) Please[medbullets.com]

  • Anemia

    hyperbilirubinemia and hemolytic anemia when exposed to oxidative stress Low enzyme activity; with hemolysis smear may show poikilocytosis, reticulocytosis, Heinz bodies,[aafp.org] The peripheral smear can also be useful for identifying megaloblasts (large, dysfunctional and immature RBCs), or hypersegmented neutrophils which are both seen in megaloblastic[clinicaladvisor.com] Hypersegmented neutrophils disappear in 1-2 weeks.[web.archive.org]

  • Posthemorrhagic Anaemia of the Newborn

    A newborn male, born vaginally, has meconium aspiration syndrome, subarachnoid hemorrhage, and neonatal jaundice due to prematurity (delivered at 29 weeks, weighing 3 lbs,[codebusters.com] neutrophil Hypochromic anaemia Hypoprothrombinaemia Idiopathic thrombocytopenic purpura Juvenile myelomonocytic leukaemia Kostmann syndrome Laminopathy Leukaemia Leucopoenia[advancedhitechlab.com] Enclosed hemorrhage and neonatal jaundice. Am J Dis Child 1961; 101:164. PubMed Google Scholar 71. Strong SJ, Corney G. The Placenta in Twin Pregnancy .[link.springer.com]

  • Southeast Asian Ovalocytosis

    Twin B, who did not have SAO, developed neonatal hyperbilirubinemia and needed only phototherapy.[ncbi.nlm.nih.gov] Oval macrocytes and hypersegmented neutrophils , Dacryocytes, fragments, and microspherocytes, Nucleated RBCs, Howell-Jolly bodies, basophilic stippling, and cabot rings Low[quizlet.com] These babies had significant anemia at birth due to hemolysis with 51.6% of them developing neonatal hyperbilirubinemia.[ncbi.nlm.nih.gov]

  • Dihydrofolate Reductase Deficiency

    There have been concerns that use of sulphonamide-containing medicines near delivery may increase the risk of hyperbilirubinemia and neonatal haemolysis in the neonate, particularly[medicinesinpregnancy.org] Diagnostics MCV ( 100 μm 3 ) homocysteine Methylmalonic acid (MMA) is normal (unlike in vitamin B 12 deficiency, where MMA is ) Hypersegmented neutrophils and pancytopenia[amboss.com] neutrophils, macro ovalocytes Back to top[pathologyoutlines.com]

  • Acquired Idiopathic Sideroblastic Anemia

    There was no history of neonatal jaundice. Two male siblings had died in infancy. Both had pallor with hepatosplenomegaly but had not been investigated.[indianpediatrics.net] Blood Smear: Oval Macrocytes and teardrops, HJ bodies and Cabot Rings, Hypersegmented neutrophils present.[quizlet.com] Macrocytic anaemia – MCV 110 with hypersegmented neutrophil nuclei – in severe cases leucopoenia and thrombocytopenia. – Hb – WCC Platelets – Serum B12 50ng – Red cell folate[almostadoctor.co.uk]

  • Ataxia - Hypogonadism - Choroidal Dystrophy Syndrome

    , Transient Familial Neonatal Hypercholanemia, Familial Hypercholesterolemia, Familial Hyperekplexia Hyperglycerolemia Hyperglycinemia, Non-ketotic Glycine Encephalopathy[sequencing.com] Umehara T, Yaguchi H, Suzuki M, Isozaki E, Mochio S (2010) Are hypersegmented neutrophils a characteristic of Boucher–Neuhauser syndrome?[springermedizin.de] Holoprosencephaly 9 Homocystinuria Hurler Syndrome Hutchinson-Gilford Progeria Syndrome, Restrictive Dermatopathy, Lethal Hydatidiform Mole, Recurrent Hydrocephalus, X-linked Hyperbilirubinemia[sequencing.com]

  • Diamond-Blackfan Anemia

    hyperbilirubinemia and hemolytic anemia when exposed to oxidative stress Low enzyme activity; with hemolysis smear may show poikilocytosis, reticulocytosis, Heinz bodies,[aafp.org] neutrophils, normal B9, B12, no evidence of parvovirus B19 infection) Elevated ADA Elevated hemoglobin F DBS: Double Blood cell Size - Macrocytic anemia.[medicowesome.com] […] with basophilic stippling; hemolysis, reticulocytosis, and Hgb S on electrophoresis in sickle cell disease RBC enzyme defects G6PD deficiency, pyruvate kinase deficiency Neonatal[aafp.org]

  • Neonatal Isoimmune Neutropenia

    New to this edition are an expanded coverage of neonatal oncology, cord blood utilization, neonatal screening, prenatal diagnosis and hyperbilirubinemia.[books.google.com] (WBCs) – leukemia Multilobed hypersegmented neutrophils – B 12 deficiency Chemistry and urine testing to ...[arupconsult.com] Laboratories may encounter a number of neutrophil abnormalities on the peripheral blood smear, including neutrophils that are hypolobated, hypersegmented, or hypogranulated[captodayonline.com]

  • Severe Congenital Hypochromic Anemia with Ringed Sideroblasts

    In some cases the activation of the UGT1A gene at birth is insufficient to handle all the red cell turnover resulting in neonatal jaundice, apparent around day 2 or 3.[themedicalbiochemistrypage.org] Megaloblastic anaemia can also be identified by the presence of neutrophils on blood film with hypersegmented nuclei (six or more lobes). 3 Vitamin B12 or folate deficiency[bpac.org.nz] […] and splenomegaly. 1 We report a case of CDA with ringed sideroblasts presenting neonatally.[annsaudimed.net]

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