Possible Causes for hypersomnia Depression The other symptoms that are associated with major depression include decrease or increase in appetite, insomnia or hypersomnia, psycho motor agitation or retardation, constant [adaa.org] Physical symptoms Fatigue Appetite loss Insomnia, which is the inability to fall asleep and stay asleep Hypersomnia, which is feeling very sleepy most of the time Sexual problems [cancer.net] […] and inflated self-esteem Melancholic features : such as loss of pleasure, weight loss, and excessive guilt Atypical features : such as mood reactivity, weight gain, and hypersomnia [goodtherapy.org] Endogenous Depression “A patient who has psychomotor retardation, hypersomnia, and gaining weight is scored as having identical symptoms as another who is agitated, sleeping badly, and has weight [theatlantic.com] Sleep Apnea More discussions about hypersomnia [medical-dictionary.thefreedictionary.com] Abstract Hypersomnia is a significant problem in about 5% of the general population. [ncbi.nlm.nih.gov] Excessive daytime drowsiness (hypersomnia) may be due to sleep apnea or to other disorders, such as narcolepsy. [newsnetwork.mayoclinic.org] Chronic Alcoholism The concept of "structural plasticity" has emerged as a potential mechanism in neurodegenerative and psychiatric diseases such as drug abuse, depression, and dementia. Chronic alcoholism is a progressive neurodegenerative disease while the person continues to abuse alcohol, though clinical and imaging studies show[…] [ncbi.nlm.nih.gov] Traumatic Brain Injury We believe that these injuries of the ARAS might be a pathogenetic mechanism of fatigue and hypersomnia in patients with TBI. [ncbi.nlm.nih.gov] This can take the form of insomnia (difficulty falling asleep) or hypersomnia (excessive sleep), with a slightly higher risk for the latter.14 Children also experience sleep [theraspecs.com] We report on patients with post-traumatic fatigue and hypersomnia who showed injury of the lower portion of the ascending reticular activating system (ARAS) between the pontine [ncbi.nlm.nih.gov] Bronchial Asthma Asthma is defined as a chronic inflammatory disorder of the airways with bronchial hyperresponsiveness and variable bronchoconstriction, and is one of the most common diseases in childhood and adolescence. Exercise-induced asthma-like symptoms and asthma are also frequently seen in highly trained athletes.[…] [ncbi.nlm.nih.gov] Dysthymic Disorder Associated symptoms include poor appetite or overeating, insomnia or hypersomnia, poor concentration or difficulty making decisions, low energy, low self-esteem and feelings [ncbi.nlm.nih.gov] During periods of depressed mood, at least 2 of the following additional symptoms are present: poor appetite or overeating, insomnia or hypersomnia, low energy or fatigue, [icd9data.com] Depressed mood for most of day Children: One year duration Adult: Two year duration Symptoms associated with depression (2 or more) Poor appetite or Overeating Insomnia or Hypersomnia [fpnotebook.com] Chronic Fatigue Syndrome There are a number of sleep disorders that can potentially lead to sleep that does not replenish energy, including: insomnia, which is trouble falling and staying asleep hypersomnia [medicalnewstoday.com] Autoantibodies to a 68/48 kDa protein in chronic fatigue syndrome and primary fibromyalgia: a possible marker for hypersomnia and cognitive disorders. [dx.doi.org] Bipolar Disorder Hypersomnia presents as excessive daytime sleepiness with a prevalence of 7.1% in general population. Hypersomnia has serious negative effects on persons functioning. [ncbi.nlm.nih.gov] Episodes are characterized by hypersomnia, cognitive impairment, feelings of derealization, and, less frequently, hyperphagia (66%), hypersexuality [53% (principally men)] [ncbi.nlm.nih.gov] Hypersomnia Hypersomnia is the opposite of insomnia. It describes over-sleeping, and it affects one-third of individuals with bipolar disorder. [tuck.com] Parkinson Disease Eric Konofal, Elias Karroum, Ebba Lohmann, Ioannis Theodorou, Alexandra Dürr and Isabelle Arnulf, Restless legs syndrome, rapid eye movement sleep behavior disorder, and hypersomnia [doi.org] Boeve, Efficacy, Safety, and Tolerability of Armodafinil Therapy for Hypersomnia Associated with Dementia with Lewy Bodies: A Pilot Study, Dementia and Geriatric Cognitive [doi.org] Muscular Dystrophy Apathy and hypersomnia are common features of myotonic dystrophy. [ncbi.nlm.nih.gov] Psychostimulants for hypersomnia (excessive daytime sleepiness) in myotonic dystrophy. [ncbi.nlm.nih.gov] Psychosis Central Hypersomnia. Seminars in Pediatric Neurology, Vol. 22, Issue. 2, p. 93. CrossRef Google Scholar Rabeyron, Thomas and Loose, Tianna 2015. [doi.org] Erin Kelty, Vlad Martyn, George O’Neil and Gary Hulse, Use of subcutaneous flumazenil preparations for the treatment of idiopathic hypersomnia: A case report, Journal of Psychopharmacology [doi.org] Primary Progressive Multiple Sclerosis We present three patients with a clinical course and cerebrospinal fluid findings consistent with a diagnosis of primary progressive multiple sclerosis (PPMS). Extensive and repeated magnetic resonance imaging (MRI) examinations showed only diffuse abnormality in brain and spinal cord, but no focal lesions. We propose[…] [ncbi.nlm.nih.gov] Epilepsy The purpose of this article is to highlight the hallmarks of epilepsy as a disease and symptom during antiquity and especially during Ancient Greece and Rome. A thorough study of texts, medical books, and reports along with a review of the available literature in PubMed was undertaken. Observations on epilepsy date[…] [ncbi.nlm.nih.gov] Hypersomnia behaviorally induced insufficient sleep syndrome, hypersomnia due to medical condition, hypersomnia due to drug or substance, hypersomnia not due to a substance or known [ncbi.nlm.nih.gov] Let's Get #BeyondSleepy Welcome to the Hypersomnia Foundation, committed to improving the lives of people living with idiopathic hypersomnia (IH) and related sleep disorders [hypersomniafoundation.org] Billiard M, Dauvilliers Y: Idiopathic hypersomnia. Sleep Med Rev 2001, 5 :351–360. Extensive review on idiopathic hypersomnia. Google Scholar 24. [doi.org] Glomerulonephritis Infection-related glomerulonephritis (IRGN) is rarely complicated with eosinophil infiltration into the glomerulus. Here we report a case of eosinophilic proliferative glomerulonephritis related with infection. A 70-year-old man with respiratory symptoms displayed hypereosinophilia, hypocomplementemia, impaired renal[…] [ncbi.nlm.nih.gov] Narcolepsy Conversely, other central hypersomnias are less well-defined disorders with variability in the phenotype, and few reliable biomarkers have been discovered so far. [ncbi.nlm.nih.gov] KEYWORDS: Cataplexy; Idiopathic hypersomnia; Kleine Levin syndrome; Narcolepsy; Pharmacotherapy [ncbi.nlm.nih.gov] The purpose of this paper is to summarize current knowledge about treatment of narcolepsy and other hypersomnias of central origin. [ncbi.nlm.nih.gov] Respiratory Muscle Paralysis […] reduction in strength and endurance of the respiratory muscles are causing alteration of the sleep structure, primarily reducing quantity of rapid eye movement (REM) sleep hypersomnia [shortnessofbreath.it] Encephalitis Migraine - Cluster - Vascular - Tension Amaurosis fugax - Foville's syndrome - Millard-Gubler syndrome - Lateral medullary syndrome - متلازمة وبر اضطراب النوم : Insomnia - Hypersomnia [marefa.org] Narcolepsy-Cataplexy Syndrome Idiopathic hypersomnia. Sleep Med Rev 2001; 5 : 349–358. 19. Kawashima M, Ohashi J, Nishida N, Tokunaga K. [nature.com] Hypersomnias are subdivided into Idiopathic Hypersomnia (persistent sleepiness lasting more than 3 months without abnormal tendencies to enter REM sleep) and Recurrent Hypersomnia [stanfordhealthcare.org] As in idiopathic hypersomnia, diagnosis depends on ruling out causes of secondary hypersomnia and performing a polysomnogram (overnight sleep test) with multiple sleep latency [hypersomniafoundation.org] Sleep Disorders Recurrent Hypersomnia Kleine-Levin Syndrome Menstrual-Related Hypersomnia 6. Idiopathic Hypersomnia with Long Sleep Time 7. [slideshare.net] She underwent a carefully conducted PSG and MSLT, which was negative for sleep disordered breathing or hypersomnia disorders. [academic.oup.com] […] covers all the parasomnias, including patient stories and vignettes, and also all the other categories of sleep disorders, including insomnia, sleep apnea, restless legs, hypersomnias [sleepfoundation.org] Pickwickian Syndrome HYPERSOMNIA VS. FATIGUE When investigating potential causes of EDS, it is important to distinguish between fatigue and excessive sleepiness, or hypersomnia. [rjjaramillo.wordpress.com] Frequently, there may not be an identifiable cause and the only diagnosis possible is that of idiopathic hypersomnia. [rjjaramillo.wordpress.com] The International Classification of Sleep Disorders (ICSD-2) includes EDS as an essential feature for three diagnostic categories: narcolepsy, hypersomnia and behaviorally [rjjaramillo.wordpress.com] Diabetes Insipidus Gestational diabetes insipidus is a very rare complication. However, undiagnosed and untreated may lead to serious complications in both mother and fetus. In this study, a case of 34-year-old female patient with diabetes insipidus associated with pregnancy was reported. We discussed process of diagnosis and[…] [ncbi.nlm.nih.gov] Hysteria Abstract This historical review presents the advances made mostly during the last 200 years on the description, concepts, theories, and (more specifically) cure of patients suffering from hysteria, a still obscure entity. The denomination of the syndrome has changed over time, from hysteria (reinvestigated by Paul[…] [ncbi.nlm.nih.gov] Severe Depressive Episode […] two criteria: the symptoms are not better explained by another psychiatric disorder AND no history of a manic or hypomanic episode. “ SIG E CAPS ” : S leep ( insomnia or hypersomnia [amboss.com] Note: In children, consider failure to make expected weight gains. (4) Insomnia or Hypersomnia nearly every day (5) psychomotor agitation or retardation nearly every day [behavenet.com] The other symptoms that are associated with major depression include decrease or increase in appetite, insomnia or hypersomnia, psycho motor agitation or retardation, constant [adaa.org] Motor Neuron Disease Motor neuron disease (MND) is occasionally aggravated by chronic infection. A misdiagnosed case of tuberculosis with MND is illustrated in a 45-year-old woman who underwent successful VATS wedge excision, which is presented herein. MND in an adult is a rare clinical entity. In order to facilitate the preoperative[…] [ncbi.nlm.nih.gov] Multiple Sclerosis Multiple sclerosis (MS) is an inflammatory demyelinating disease of central nervous system and it is associated with an impaired motor function status. The efficacy of rehabilitation in promoting functional recovery and increasing quality of life in MS patients has been demonstrated. A 47-year-old woman was diagnosed[…] [ncbi.nlm.nih.gov] Kleine-Levin Syndrome Kleine-Levin syndrome and menstrual-related hypersomnia are rare idiopathic sleep disorders occurring primarily in adolescence. [ncbi.nlm.nih.gov] Idiopathic Hypersomnia: A series of 42 Patients. Brain 1997;120:1423-35. 4. Black EJ, Nishino S, Brooks NS. [doi.org] Kleine-Levin syndrome and periodic hypersomnia are often misdiagnosed initially because there is no objective test for these conditions. [ncbi.nlm.nih.gov] Congenital Non-Goitrous Hypothyroidism Type 4 Effect of levothyroxine on prolonged nocturnal sleep time and excessive daytime somnolence in patients with idiopathic hypersomnia. [glowm.com] Atypical Depression OBJECTIVE: In this study, we used a strict definition of hypersomnia and tested if the association between overeating-hypersomnia remained positive and significant. [ncbi.nlm.nih.gov] We found that: (1) younger age was positively associated with hypersomnia and negatively associated with leaden paralysis, while middle age was positively associated with [ncbi.nlm.nih.gov] RESULTS: Atypical features of mood reactivity and at least one reversed vegetative symptom of hypersomnia, hyperphagia or weight gain (25.2% patients) were predictive of pharmacotherapy [ncbi.nlm.nih.gov]
