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211 Possible Causes for Hypersomnia, Sleep Disturbance, Weight Gain

  • Endogenous Depression

    Anticholinergic effects, weight gain and orthostatic hypotension were more frequent in the clomipramine group. No biological treatment-related changes were observed.[ncbi.nlm.nih.gov] “A patient who has psychomotor retardation, hypersomnia, and gaining weight is scored as having identical symptoms as another who is agitated, sleeping badly, and has weight[theatlantic.com] Overall, there was little support for the prediction of a difference in short- or long-term outcome between patients with and without EEG sleep disturbances.[ncbi.nlm.nih.gov]

  • Narcolepsy-Cataplexy Syndrome

    Other, non specific, clinical signs include hypnagogic hallucinations, sleep paralysis, insomnia, hypnopompic hallucinations and weight gain.[orpha.net] Idiopathic hypersomnia without cataplexy or REM sleep abnormalities may represent a third phenotype, although most cases of idiopathic hypersomnia are probably unrelated to[ncbi.nlm.nih.gov] A 20-year-old male presented with a 12-year history of excessive daytime sleepiness and sudden muscle weakness caused by laughter and disturbed nocturnal sleep.[ncbi.nlm.nih.gov]

  • Prader-Willi Syndrome

    This can result in rapid weight gain and morbid obesity.[nlm.nih.gov] Our patient presented at two years of age with hypersomnia and narcoleptic episodes with cataplectic features.[ncbi.nlm.nih.gov] Prader-Willi syndrome: sorting out the relationships between obesity, hypersomnia, and sleep apnea.[ncbi.nlm.nih.gov]

  • Depression

    Winter depression, typically accompanied by social withdrawal, increased sleep, and weight gain, predictably returns every year in seasonal affective disorder.[nimh.nih.gov] Physical symptoms Fatigue Appetite loss Insomnia, which is the inability to fall asleep and stay asleep Hypersomnia, which is feeling very sleepy most of the time Sexual problems[cancer.net] Patients with unimpaired sleep at baseline showed greater improvements over time than those with sleep disturbances.[ncbi.nlm.nih.gov]

  • Obstructive Sleep Apnea

    We report a patient with anti-muscle kinase receptor MG with severe OSA and hypoventilation that resolved upon successful treatment of MG despite a 60-lb weight gain.[ncbi.nlm.nih.gov] […] be reported by another person Gasping for air during sleep Awakening with a dry mouth Morning headache Difficulty staying asleep (insomnia) Excessive daytime sleepiness (hypersomnia[mayoclinic.com] […] rating of sleep disturbance (visual analogue scale from 0 (not disturbed) to 10), apnoea-hypopnoea index, and health related quality of life (SF-36).[ncbi.nlm.nih.gov]

  • Chronic Alcoholism

    Heavy drinking can hinder the body from burning fat, leading to more weight gain.[redeyechicago.com] disturbances). [9] Ferenci P, Lockwood A, Mullen K, et al.[bestpractice.bmj.com] Increases in your blood pressure can also be caused by weight gain from excessive drinking 3.[drinkaware.co.uk]

  • Narcolepsy

    Four months after initiation of methylphenidate therapy the increased daytime sleepiness improved and excessive weight gain stopped.[ncbi.nlm.nih.gov] Conversely, other central hypersomnias are less well-defined disorders with variability in the phenotype, and few reliable biomarkers have been discovered so far.[ncbi.nlm.nih.gov] Narcolepsy, a sleep disturbance that is characterized by sudden, uncontrollable spells of sleep during the day, with disturbances of sleep at night.[britannica.com]

  • Seasonal Mood Disorder

    When nerve cell pathways in the brain that regulate mood don't function normally, the result can be feelings of depression , along with symptoms of fatigue and weight gain[webmd.com] Instead, they complain of hypersomnia (sleepiness) and overeating with a craving for carbohydrates, along with a depressed mood and lowered self-esteem.[theconversation.com] Other research has shown that people with SAD experience more insomnia and sleep disturbances, and are more prone to nodding off at work.[health.com]

  • Kleine-Levin Syndrome

    If you experience increased hunger and overeat during episodes, you may be more likely to experience weight gain.[healthline.com] Kleine-Levin syndrome and menstrual-related hypersomnia are rare idiopathic sleep disorders occurring primarily in adolescence.[ncbi.nlm.nih.gov] Abstract Narcolepsy is a chronic neurologic disorder with the abnormal regulation of the sleep-wake cycle, resulting in excessive daytime sleepiness, disturbed nocturnal sleep[ncbi.nlm.nih.gov]

  • Atypical Depression

    […] increased appetite (comfort eating), often with significant weight gain.[drsharma.ca] OBJECTIVE: In this study, we used a strict definition of hypersomnia and tested if the association between overeating-hypersomnia remained positive and significant.[ncbi.nlm.nih.gov] Most typical symptoms of not typical depression include: 1) increased appetite (on-going hunger) and weight gain; 2) sleep disturbances (sleepiness or excessive sleep); 3)[women-info.com]

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