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28 Possible Causes for Hypertonicity of the Lower Limbs, Hyporeflexia, Sensation Normal

  • Autosomal Recessive Lower Motor Neuron Disease with Childhood Onset

    Patients typically present during infancy or early childhood with progressive weakness, hypotonia , muscle atrophy , hyporeflexia/areflexia, and varying degrees of bulbar[amboss.com] limbs, hypertonic urinary bladder, and impaired vibration sense.[clinicalgate.com] DSMA4 is characterized by childhood onset, generalized muscle weakness and atrophy with denervation and normal sensation. Bulbar symptoms and pyramidal signs are absent.[uniprot.org]

  • Arachnoiditis

    Clinical description Patients present with chronic, persistent deafferentiation pain in the lower back, limbs and trunk that is increased by activity, hyporeflexia, loss of[orpha.net] Methods Examination revealed generalized weakness and hypertonicity of both lower limbs with loss of all sensory modalities below D7.[doi.org] : Mental status; Hearing; Sensation; Bladder, Bowel & Sexual functions Laboratory Somatosensory evoked potentials: Prolonged cortical responses & central sensory delay Return[neuromuscular.wustl.edu]

  • Lower Motor Neuron Syndrome with Late-Adult Onset

    sensation -normal nerve conduction velocities -denervation on EMG -dec. # of motor units -muscle biopsy shows atrophic fibers & fiber grouping -seen in MRI -present: lower[brainscape.com] limbs, hypertonic urinary bladder, and impaired vibration sense.[clinicalgate.com] Common features are muscle weakness (distal or proximal) with atrophy and hyporeflexia, but no sensory involvement. They can be acquired or hereditary.[em-consulte.com]

  • X-linked Parkinsonism-Spasticity Syndrome

    There was a mild impairment of vibration sense, but proprioception and superficial sensation were normal.[journals.plos.org] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com] […] allocated to ADCA I being: progressive cerebellar gait and limb ataxia with pyramidal and extrapyramidal involvement, slow saccadic eye movements, supranuclear ophthalmoplegia, hyporeflexia[neuroweb.us]

  • Hemiparesis

    Strength was 0/5 on right arm and 3/5 on left arm. 1/5 in the legs, with right-sided hypesthesia, hyporeflexia, and a right Babinski sign. Head CT was unremarkable.[journals.lww.com] Mass grasp / - Pronation/supination / - Rebound test of holmes / - Tapping (hand) / - Drawing a circle (hand and foot) / - Fixation/position holding (upper and lower limb[slideshare.net] sensation, but that they moved in parallel when the joint position sense was impaired.[jstage.jst.go.jp]

  • Autosomal Dominant Spastic Paraplegia Type 9A

    There was a mild impairment of vibration sense, but proprioception and superficial sensation were normal.[journals.plos.org] limb hypertone.[slideheaven.com] Hyperreflexia, extensor plantar response and increased muscle tone are the recognized UMN signs where as the weakness, muscle wasting, hyporeflexia, muscle cramps, and fasciculations[explainmedicine.com]

  • Spastic Paraplegia

    There was a mild impairment of vibration sense, but proprioception and superficial sensation were normal.[journals.plos.org] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com] Hyperreflexia, extensor plantar response and increased muscle tone are the recognized UMN signs where as the weakness, muscle wasting, hyporeflexia, muscle cramps, and fasciculations[explainmedicine.com]

  • Cerebral Palsy

    Infantile spinal muscular atrophy, muscular dystrophies, and neuromuscular junction disorders associated with hypotonia and hyporeflexia usually lack signs of cerebral disease[merckmanuals.com] All had spasticity affecting predominantly the lower limbs, although 2 also had mild hypertonia and ataxia of the upper limbs.[ncbi.nlm.nih.gov] […] earlier than 18 months of age) For the mother Any adverse effects severe enough to stop treatment Postpartum haemorrhage (however reported by the trialists) Mode of birth (normal[doi.org]

  • Spastic Paraparesis-Deafness Syndrome

    There was a mild impairment of vibration sense, but proprioception and superficial sensation were normal.[journals.plos.org] […] bladder) and extensor plantar responses with weakness of a pyramidal distribution in the lower limbs.[ruralneuropractice.com] Hyperreflexia, extensor plantar response and increased muscle tone are the recognized UMN signs where as the weakness, muscle wasting, hyporeflexia, muscle cramps, and fasciculations[explainmedicine.com]

  • Autosomal Dominant Spastic Paraplegia Type 31

    Peripheral nerves are normal in patients with pure HSP. 38. Vibratory sensation is often mildly diminished in the distal lower extremities. 39.[slideshare.net] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com] Cough Abnormality of visual evoked potentials Abnormality of color vision Distal lower limb amyotrophy Proximal muscle weakness Corpus callosum atrophy Spastic dysarthria Hyporeflexia[mendelian.co]

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