Create issue ticket

45 Possible Causes for Hypertonicity of the Lower Limbs, Sensation Normal, Spastic Gait

  • Autosomal Recessive Lower Motor Neuron Disease with Childhood Onset

    JALS is characterized by onset during childhood (mean age of onset is 6.5 years), spasticity of facial muscles, uncontrolled laughter, spastic dysarthria, spastic gait, inconstant[cmm.ucsd.edu] limbs, hypertonic urinary bladder, and impaired vibration sense.[clinicalgate.com] DSMA4 is characterized by childhood onset, generalized muscle weakness and atrophy with denervation and normal sensation. Bulbar symptoms and pyramidal signs are absent.[uniprot.org]

  • Cerebral Palsy

    BACKGROUND: Previous researchers reported that popliteal angle did not correlate well with knee angle during gait in individuals with spastic cerebral palsy (CP).[ncbi.nlm.nih.gov] […] earlier than 18 months of age) For the mother Any adverse effects severe enough to stop treatment Postpartum haemorrhage (however reported by the trialists) Mode of birth (normal[doi.org] All had spasticity affecting predominantly the lower limbs, although 2 also had mild hypertonia and ataxia of the upper limbs.[ncbi.nlm.nih.gov]

  • Paraparesis

    BACKGROUND: The aim of this study was to investigate the lower limb muscle coactivation and its relationship with muscles spasticity, gait performance, and metabolic cost[ncbi.nlm.nih.gov] Sensory examination showed loss of vibration in lower limbs with normal sensation to pinprick, fine touch and propioception.[n.neurology.org] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com]

  • Hereditary Spastic Paraplegia

    For many subjects with an ATL1 mutation, spastic gait begins in early childhood and does not significantly worsen, even over many years; such cases resemble spastic diplegic[ncbi.nlm.nih.gov] Sensation was normal. Ophthalmological examination was normal.[scielo.br] […] and weakness - limited mainly to the lower extremities.[whonamedit.com]

  • X-Linked Spastic Paraplegia Type 2

    There are a number of references which give descriptions of a spastic gait - here's part of one I like: When a person has a spastic gait, his legs are typically weak and abnormally[hspjourney.blogspot.com] There was a mild impairment of vibration sense, but proprioception and superficial sensation were normal.[journals.plos.org] limb hypertone.[slideheaven.com]

  • Autosomal Dominant Spastic Paraplegia Type 31

    […] characterized by a pure phenotype of proximal weakness of the lower extremities with spastic gait and brisk reflexes, with a bimodal age of onset of either childhood or adulthood[orpha.net] Peripheral nerves are normal in patients with pure HSP. 38. Vibratory sensation is often mildly diminished in the distal lower extremities. 39.[slideshare.net] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com]

  • Autosomal Recessive Spastic Paraplegia Type 46

    Table 134-1 Genetic Types of HSP (updated from Fink JK, 2011) View Table Favorite Table Download (.pdf) Table 134-1 Genetic Types of HSP (updated from Fink JK, 2011) Spastic[mhmedical.com] There was a mild impairment of vibration sense, but proprioception and superficial sensation were normal.[journals.plos.org] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com]

  • Autosomal Dominant Spastic Paraplegia Type 4

    The clinical phenotype includes asymptomatic patients, mildly affected individuals with spastic gait but able to walk independently, and severely affected patients who were[link.springer.com] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com] Weakness: Some patients Distal Hands & Feet Fasciculations Sensation: Normal or Reduced (Panmodal; Posterior column) Bladder: Often normal Progression Over few years or Slow[neuromuscular.wustl.edu]

  • Autosomal Recessive Spastic Paraplegia Type 48

    SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity.[centogene.com] Strength, coordination, and sensation were normal on bedside examination. No dementia was evident (Folstein mini-mental status examination score 30).[ng.neurology.org] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com]

  • Autosomal Dominant Spastic Paraplegia Type 6

    0002061 Progressive Worsens with time 0003676 Seizures Seizure 0001250 Spastic gait Spastic walk 0002064 Urinary bladder sphincter dysfunction 0002839 Urinary urgency Overactive[rarediseases.info.nih.gov] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com] There was a mild impairment of vibration sense, but proprioception and superficial sensation were normal.[journals.plos.org]