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58 Possible Causes for Hypertonicity of the Lower Limbs, Spastic Gait

  • Cerebral Palsy

    BACKGROUND: Previous researchers reported that popliteal angle did not correlate well with knee angle during gait in individuals with spastic cerebral palsy (CP).[ncbi.nlm.nih.gov] All had spasticity affecting predominantly the lower limbs, although 2 also had mild hypertonia and ataxia of the upper limbs.[ncbi.nlm.nih.gov] Abstract To compare medial gastrocnemius muscle-tendon structure, gait propulsive forces, and ankle joint gait kinetics between typically developing children and those with[ncbi.nlm.nih.gov]

  • Hereditary Spastic Paraplegia

    For many subjects with an ATL1 mutation, spastic gait begins in early childhood and does not significantly worsen, even over many years; such cases resemble spastic diplegic[ncbi.nlm.nih.gov] […] and weakness - limited mainly to the lower extremities.[whonamedit.com] Characteristic clinical features comprise progressive spastic gait, cognitive impairment, and ataxia.[ncbi.nlm.nih.gov]

  • X-Linked Spastic Paraplegia Type 2

    There are a number of references which give descriptions of a spastic gait - here's part of one I like: When a person has a spastic gait, his legs are typically weak and abnormally[hspjourney.blogspot.com] limb hypertone.[slideheaven.com] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com]

  • Autosomal Dominant Spastic Paraplegia Type 10

    gait Spastic walk 0002064 Spastic paraplegia 0001258 Urinary bladder sphincter dysfunction 0002839 Urinary incontinence Loss of bladder control 0000020 Showing of 38 Last[rarediseases.info.nih.gov] limb spasticity, pyramidal weakness, hyperreflexia and hypertonic bladder involvement.[medicbind.com] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com]

  • Autosomal Dominant Spastic Paraplegia Type 31

    […] characterized by a pure phenotype of proximal weakness of the lower extremities with spastic gait and brisk reflexes, with a bimodal age of onset of either childhood or adulthood[orpha.net] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com] […] with spastic gait and brisk reflexes, with a bimodal age of onset of either childhood or adulthood ( 30 years).[rarediseases.info.nih.gov]

  • Autosomal Recessive Spastic Paraplegia Type 46

    Table 134-1 Genetic Types of HSP (updated from Fink JK, 2011) View Table Favorite Table Download (.pdf) Table 134-1 Genetic Types of HSP (updated from Fink JK, 2011) Spastic[mhmedical.com] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com] 0002061 Optic atrophy 0000648 Paraplegia Leg paralysis 0010550 Progressive Worsens with time 0003676 Spastic gait Spastic walk 0002064 Urinary incontinence Loss of bladder[rarediseases.info.nih.gov]

  • Autosomal Dominant Spastic Paraplegia Type 6

    0002061 Progressive Worsens with time 0003676 Seizures Seizure 0001250 Spastic gait Spastic walk 0002064 Urinary bladder sphincter dysfunction 0002839 Urinary urgency Overactive[rarediseases.info.nih.gov] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com] Showing of 26 80%-99% of people have these symptoms Babinski sign 0003487 Gait disturbance Abnormal gait Abnormal walk Impaired gait [ more ] 0001288 Impaired vibratory sensation[rarediseases.info.nih.gov]

  • Autosomal Recessive Spastic Paraplegia Type 26

    Background: Hereditary spastic paraplegias (HSP) are degenerative diseases of upper motor neurons characterized by a progressive spastic gait disorder which are phenotypically[mdsabstracts.org] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com] […] form of complicated spastic paraplegia characterized by onset in the first 2 decades of life of gait abnormalities due to lower limb spasticity and muscle weakness.[malacards.org]

  • Autosomal Dominant Spastic Paraplegia Type 37

    […] by a childhood- to adulthood-onset of slowly progressive spastic gait, extensor plantar responses, brisk tendon reflexes in arms and legs, decreased vibration sense at ankles[orpha.net] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com] spastic paraplegia characterized by a slowly progressive and relatively benign spastic paraplegia presenting in adulthood with spastic gait, lower limb hyperreflexia, extensor[mendelian.co]

  • Autosomal Recessive Spastic Paraplegia Type 48

    SPG4 is characterized by insidiously progressive bilateral lower-limb gait spasticity.[centogene.com] The lower limb spasticity is the prominent finding on examination, particularly in the hamstrings, quadriceps, and ankles.[jnnp.bmj.com] […] paraplegia (HSP) is heterogeneous group of genetically inherited disorders mainly characterized by spastic gait impairment.[hspersunite.org.au]

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