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93 Possible Causes for Hypertrichosis of Eyebrows, Splenomegaly

  • Fucosidosis

    […] the symptoms are usually classified as: Type I (also called severe) begins in the first 3-18 months of life coarse facial features enlarged liver (hepatomegaly), spleen (splenomegaly[dermaamin.com] […] spasticity manifests coarse facies dwarfism and other muscoskeletal anomalies recurrent respiratory infections angiokeratomas organomegaly : glossomegaly , hepatomegaly , splenomegaly[radiopaedia.org] […] respiratory infections [ more ] 0002205 Scoliosis Abnormal curving of the spine 0002650 Shield chest 0000914 Short stature Decreased body height Small stature [ more ] 0004322 Splenomegaly[rarediseases.info.nih.gov]

  • Alpha-Mannosidosis

    The earlier system delineated a more severe 'type I,' which shows infantile onset, rapid mental deterioration, hypotonia, splenomegaly, severe dysostosis multiplex, and severe[diseaseinfosearch.org] […] onset of the most severe form, type III, begins within the first months of life and includes a quick progression of intellectual disability , liver and spleen enlargement ( splenomegaly[ipfs.io] Splenomegaly is minimal. Respiratory infections and otitis media are frequent.[emedicine.medscape.com]

  • Hepatoerythropoietic Porphyria

    Other commons signs and symptoms include hemolytic anemia, hyperpigmented skin, and splenomegaly. Onset is typically during infancy and early childhood.[visualdx.com] Hypertrichosis of temporal and malar facial areas is often observed. Heavier growth of eyebrow, beard and limb hair may also occur. Figure 1.[clinicalpainadvisor.com] There may be splenomegaly and haemolytic anaemia. Avoidance of sunlight is the only treatment.[gpnotebook.co.uk]

  • Wiedemann-Steiner Syndrome

    Long eyelashes Dysostosis multiplex Hyperreflexia Smooth philtrum Hirsutism Recurrent respiratory infections Pectus excavatum Thick vermilion border Atrial septal defect Splenomegaly[mendelian.co] […] cubiti, facial dysmorphism (hypertelorism, long eyelashes, thick eyebrows, downslanted, vertically narrow, long palpebral fissures, wide nasal bridge, broad nasal tip, long[orpha.net] Facial characteristics include long eyelashes, thick or arched eyebrows with a lateral flare, and downslanting and vertically narrow palpebral fissures.[uniprot.org]

  • Rubinstein-Taybi Syndrome

    Splenomegaly was observed at 21 years of age, and a detailed immunological analysis of this patient was performed by Torres (2008) 13.[scielo.br] The clinical data of our cohort evidenced frequent signs such as arched eyebrows, epicanthus, synophrys and/or frontal hypertrichosis and broad phalanges that, previously[ncbi.nlm.nih.gov] The common abnormalities include hypertrichosis and hirsuitism,heavy eyebrows, prominent beaked nose,hypoplastic maxilla, lowest ears and skeletal anomalies including broad[ispub.com]

  • Gingival Fibromatosis-Progressive Deafness Syndrome

    Report of an affected family with associated splenomegaly and skeletal and soft-tissue abnormalities. Oral Surg 1964: 17: 339-351.[documentslide.com] Since variable expressionoccurs in autosomal dominant conditions and synophris,bushy eyebrows and hypertrichosis were not present inunaffected family members, the diagnosis[docslide.net] It occurs either as an isolated disease or combined with some rare syndromes like Zimmerman‑Laband syndrome (defects of bone, nail, ear, nose and splenomegaly), Murray‑Puretic‑Drescher[ijcdc.com]

  • Telangiectasia Macularis Eruptiva Perstans

    Flushing, blistering, pruritus, cardiac arrhythmias, dyspnea, asthma exacerbations, hypotension, gastrointestinal upset, acid reflux, peptic ulcer disease, diarrhea, splenomegaly[bloodjournal.org] , broad nasal root, fusion of the medial eyebrows, sensorineural deafness) Ash-leaf spots of tuberous sclerosis (usually present in first year of life / trunk, limbs / ash-leaf[pcds.org.uk] […] at higher risk of being associated with systemic disease.[4] Symptoms of systemic involvement include flushing, dyspnea, abdominal pain, diarrhea, hypotension, syncope, splenomegaly[jcadonline.com]

  • Gingival Fibromatosis-Hypertrichosis Syndrome

    Hereditary gingival fibromatosis: Report of an affected family with associated splenomegaly and skeletal and soft tissue abnormalities.[ijdr.in] An example of naevoid circumscribed hypertrichosis is the presence of a solitary and very bushy eyebrow.[dermnetnz.org] Report of an affected family with associated splenomegaly, skeletal and soft-tissue abnormalities. Oral Surg. 1964;31:691-5. Chacon-Camacho, Vázquez J, Zenteno JC.[msjonline.org]

  • Lytic Bone Lesion

    […] carinatum - Peripheral neuropathy - Polycystic kidneys - Repeat respiratory infections - Speech troubles / aphasia / dysphasia / echolalia / mutism / logorrhea / dysprosodia - Splenomegaly[csbg.cnb.csic.es] […] of the medial part of the eyebrows” is present, meaning excessive hair growth in the patients’ eyebrow region, most likely leading to a unibrow. [ 6 ] The fourth symptom,[senyawa-kimia.blogspot.com] […] infections respiratory infections, recurrent Susceptibility to respiratory infections [ more ] 0002205 Rough bone trabeculation 0100670 Skin ulcer Open skin sore 0200042 Splenomegaly[rarediseases.info.nih.gov]

  • Familial Angiolipomatosis

    […] cell carcinoma印環細胞癌 sinusoid類洞 small intestine小腸 spasm of the esophagus食道痙攣 sphincter of Oddi (SO)オッジ括約筋(オッジ筋) splanchnic nerve内臓神経 splanchnic plexus内臓神経叢 splenectomy脾摘術 splenomegaly[tokyo-med.ac.jp] […] of the medial part of the eyebrows, white forelock, heterochromia iridis; and deaf-mutism. 40 , 41 There are now four recognised variants of Waardenburg syndrome (types I–IV[nature.com] , which had six main features: lateral displacement of the medial canthi combined with dystopia of the lacrimal punctum and blepharophimosis; prominent broad nasal root; hypertrichosis[nature.com]

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