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965 Possible Causes for Hypertrophic Osteoarthropathy, Leukocyte Alkaline Phosphatase Increased, Wide Space Between the First and Second Toe

  • Portal Cirrhosis

    Abstract A recent paper by Vogl and Goldfischer (1) outlines the development of our ideas of hypertrophic osteoarthropathy.[annals.org] osteoarthropathy Constitutional symptoms, including anorexia, fatigue, weakness, and weight loss Cruveilhier-Baumgarten murmur—a venous hum in patients with portal hypertension[aafp.org] View/Print Table TABLE 2 Common Physical Examination Findings in Patients with Cirrhosis Abdominal wall vascular collaterals (caput medusa) Ascites Asterixis Clubbing and hypertrophic[aafp.org]

    Missing: Wide Space Between the First and Second Toe
  • Macronodular Cirrhosis

    Nail changes: Clubbing, hypertrophic osteoarthropathy, and the Dupuytren contracture are seen.[ncbi.nlm.nih.gov] It is not specific for cirrhosis and can therefore be due to a number of conditions [18] Hypertrophic osteoarthropathy.[en.wikipedia.org]

    Missing: Wide Space Between the First and Second Toe
  • Hepatocellular Carcinoma

    osteoarthropathy Histology bronchial varies bronchioalveolar growth along preexisting structures destruction of alveolar architecture or invasion Treatment surgical resection[medbullets.com] […] bronchial most commonly presents with hemoptysis bronchioalveolar can present like pneumonia consolidation on chest radiograph and copious sputum production can result in hypertrophic[medbullets.com]

    Missing: Wide Space Between the First and Second Toe
  • Inflammatory Bowel Disease Type 1

    View or Print All Sections Definition & Facts Crohn’s disease is a chronic, or long lasting, disease that causes inflammation and irritation in your digestive tract. Symptoms & Causes The most common symptoms of Crohn’s disease are diarrhea, cramping and pain in your abdomen, and weight loss. Doctors aren’t sure[…][niddk.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Ulcerative Colitis

    A 65-year-old Japanese man was referred to our hospital for the further assessment of cough and dyspnea. He had a history of ulcerative colitis for which he was receiving treatment. Chest computed tomography showed a crazy-paving pattern. His bronchoalveolar lavage fluid had a milky appearance, and a[…][ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Colonic Crohn Disease

    Abstract Immune mechanisms, possibly involving cell-surface molecules such as CD44, have been invoked to explain the pathogenesis of inflammatory bowel disease. We used monoclonal antibodies against epitopes encoded within the variable region of CD44 to investigate CD44 isoform expression in colon, small intestine, and[…][ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Down Syndrome

    A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] spacing, often with a deep plantar groove between the first and second toes.[doi.org] […] fissures, Brushfield spots, small mouth, small ears, excessive skin at the nape of the neck, single transverse palmar crease, and short fifth finger with clinodactyly and wide[doi.org]

    Missing: Hypertrophic Osteoarthropathy
  • Primary Myelofibrosis

    alkaline phosphatase (LAP) score is increased Treatment Reduced intensity allogeneic stem cell transplant if intermediate to high risk or palliation of extramedullary hematopoiesis[pathologyoutlines.com] Osteosclerosis, hypertrophic osteoarthropathy and periostitis: may cause severe joint and bone pain.[patient.info] osteoarthropathy, 345 gray platelet syndrome, 346 systemic lupus erythematosus, 239–242 polyarteritis nodosa, 245 hypereosinophilic syndrome, 347,348 kala azar, 349 primary[patient-help.com]

    Missing: Wide Space Between the First and Second Toe
  • Leukemoid Reaction

    Unlike CML, leukocyte alkaline phosphatase is increased and the bcr/abl translocation is absent.[wakemedicine.wordpress.com] . , Green , B. ( 1977 ) Hypertrophic osteoarthropathy associated with nasopharyngeal carcinoma . American Journal of Roentgenology 128 : 679 – 681 .[cambridge.org] The leukemoid reaction is distinguished from chronic myelogenous leukemia by an increased leukocyte alkaline phosphatase, and generally, lack of thrombocytopenia.[pancreas.imedpub.com]

    Missing: Wide Space Between the First and Second Toe
  • Liver Failure

    osteoarthropathy Constitutional symptoms, including anorexia, fatigue, weakness, and weight loss Cruveilhier-Baumgarten murmur—a venous hum in patients with portal hypertension[aafp.org] View/Print Table TABLE 2 Common Physical Examination Findings in Patients with Cirrhosis Abdominal wall vascular collaterals (caput medusa) Ascites Asterixis Clubbing and hypertrophic[aafp.org] Testicular atrophy TABLE 2 Common Physical Examination Findings in Patients with Cirrhosis Abdominal wall vascular collaterals (caput medusa) Ascites Asterixis Clubbing and hypertrophic[aafp.org]

    Missing: Wide Space Between the First and Second Toe

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