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27 Possible Causes for Hyperuricemia, Immunoglobulin G Increased, Pruritus

  • Non-Hodgkin Lymphoma

    Tumor lysis syndrome is heralded by the development of hypocalcemia, hyperkalemia, hyperphosphatemia and hyperuricemia, as well as acute renal failure; consult nephrology[clinicaladvisor.com] Common examples are follicular lymphoma and marginal zone lymphoma.Few subtypes of Non-Hodgkin lymphoma may also present with rash, pruritus, generalized aches and pains.[symptoma.com] One indicator of the potential for tumor lysis syndrome is an elevated plasma lactate dehydrogenase level or hyperuricemia at the time of diagnosis.[emedicine.com]

  • Multiple Myeloma

    Not recognizing hyperuricemia.[clinicaladvisor.com] Consistent with a hypomorphic effect, we find that the MM risk allele also associates with reduced levels of immunoglobulin A (IgA) and G (IgG) in healthy subjects ( P 8.6[nature.com] Her pruritus resolved, but the lesions persisted. Footnotes Competing interests: None declared. This article has been peer reviewed.[cmaj.ca]

  • Myeloproliferative Disease

    […] leukemia and agnogenic myeloid metaplasia Easy bruising, bleeding, and/or symptoms of thrombosis Swollen, painful joint(s) secondary to gouty arthritis that is secondary to hyperuricemia[emedicine.com] Common symptoms include: headaches blurred vision fatigue weakness dizziness itchiness (pruritus) night sweats raised blood pressure (hypertension).[leukaemia.org.au] Clinical description Symptoms are often insidious at onset and may include headache, dizziness, vertigo, tinnitus, visual disturbances, and pruritus after bathing, a ruddy[orpha.net]

  • Polycythemia Vera

    The maximum-tolerated dose of gandotinib was 120mg daily, based on dose-limiting toxicities of blood creatinine increase or hyperuricemia at higher doses.[ncbi.nlm.nih.gov] A detailed MEDLINE search for all English language articles related to PV, PV-associated pruritus and aquagenic pruritus that were published from 1965 till date was carried[ncbi.nlm.nih.gov] Increased cell turnover may cause hyperuricemia, increasing the risk of gout and urate kidney stones.[merck.com]

  • Hodgkin's Disease

    She remained with a low level of pruritus until her death in July 2008, at the same dose of thalidomide.[ncbi.nlm.nih.gov] […] weeks primigravida was referred from the Emergency Department to the Medical Unit Khyber Teaching Hospital-MTI, Peshawar with four weeks of fever, progressive jaundice, pruritus[ncbi.nlm.nih.gov] Integumentary: Diffuse pruritus may appear because of lymph stasis. Head and Neck: Most patient may present with painless cervical lymphadenopathy.[symptoma.com]

  • Waldenstrom Macroglobulinemia

    IgM triggers the increased production of immunoglobulin G and the complement fixation (a mechanism) required for effective antibody response.[healthcentral.com] Increased viscosity (thickness) of the blood may result in circulatory impairment, weakness, neurologic disorders, and fatigue.[healthcentral.com] It is the first immunoglobulin the body produces when challenged by antigens and is found in circulating fluids.[healthcentral.com]

  • Sarcoidosis

    Indications for Corticosteroid Therapy in Cases of Sarcoidosis Starting with stage II, with simultaneous restricted pulmonary function Hypercalcemia and hyperuricemia (threat[lecturio.com] We report the case of a 39-year-old woman who presented to the dermatologist with a 2-year history of vulvar pruritus.[ncbi.nlm.nih.gov] Since both may manifest with hyperuricemia and similar clinical findings, demonstration of monosodium urate crystals phagocytozed by neutrophils is diagnostic.[doi.org]

  • Sickle Cell Disease

    Sickle RBCs have increased immunoglobulin G (IgG) on the cell surface.[emedicine.com] These include nausea, vomiting, pruritus, constipation, mental changes, tolerance, dependence, hyperalgesia, and addiction.[doi.org] […] also causes seizures with a reported prevalence of 1.2% if given in sufficiently large doses. 27 Morphine is the most histaminergic opioid 28 and is associated with severe pruritus[doi.org]

  • Hereditary Spherocytosis

    The results of anti-HPV immunoglobulin M (IgM) and immunoglobulin G (IgG) measured at admission were both positive, and HPV-B19 deoxyribonucleic acid (DNA) increased to 10[bmcresnotes.biomedcentral.com] A 18 year old Turkish patient with hereditary spherocytosis was admitted to hospital with pruritus and severe jaundice.[ncbi.nlm.nih.gov] Treatment with ursodesoxycholic acid and intermittent therapy with prednisone reduced pruritus and jaundice with concomitant improvement of blood test.[ncbi.nlm.nih.gov]

  • Cryptogenic Cirrhosis

    […] significantly higher prevalence of metabolic syndrome (12% vs 54%, respectively), overweight/obesity, high BMI, impaired glucose tolerance, high blood pressure, dyslipidemia, hyperuricemia[ncbi.nlm.nih.gov] […] anorexia, weight loss Specific (due to impaired liver function): Impaired protein synthesis (leukonychia [white nails], ascites, bruising) Impaired biliary excretion (jaundice, pruritus[pathologyoutlines.com] […] splenomegaly due to portal hypertension or the direct effects of alcohol on bone marrow Coagulopathy due to impaired liver synthetic function, vitamin K deficiency, or both Pruritus[merckmanuals.com]

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