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54 Possible Causes for Hyperuricemia, Iron Increased, Reticulocyte Count Decreased

  • Chronic Alcoholism

    Cardiovascular system: Holiday heart syndromes Dilatative cardiomyopathy caused by alcoholism Arterial hypertension Apoplexy Coronary heart disease Metabolism : Hypertriglyceridemia Hyperuricemia[flexikon.doccheck.com] Coexisting iron accumulation or chronic hepatitis C increases risk of hepatocellular carcinoma.[merckmanuals.com] Other factors that may trigger type 1 PCT include oestrogen, iron and viral infections (especially hepatitis C).[dermnetnz.org]

  • Pernicious Anemia

    Values obtained before treatment with cyanocobalamin were compared with those found during peak reticulocyte count.[ncbi.nlm.nih.gov] Individuals suffering iron deficiency might take oral iron supplements and increase their dietary iron intake, while individuals suffering from pernicious anemia might receive[livestrong.com] Response should be monitored by reticulocyte counts, lactic dehydrogenase (LDH), and an appropriate rise in hemoglobin levels.[emedicine.medscape.com]

  • Acute Myelocytic Leukemia

    Hydration and allopurinol or rasburicase are used for treatment of hyperuricemia, hyperphosphatemia, hypocalcemia, and hyperkalemia (ie, tumor lysis syndrome ) caused by the[merckmanuals.com] An iron stain usually shows increased iron stores and may show ring sideroblasts (Figure 2, B [inset]).[archivesofpathology.org] The potential for neurotoxicity has aroused concern about the use of high-dose cytarabine in elderly patients who, ironically, have a higher likelihood of having drug-resistant[doi.org]

  • Leukemia

    Hyperuricemia and a slightly raised lactate dehydrogenase (LDH) are common features.[web.archive.org] […] factors) Special considerations apply to the treatment of the following: Burkitt leukemia Ph ALL ALL in older children and younger adults Relapsed ALL ALL in patients with hyperuricemia[emedicine.medscape.com]

  • Hereditary Spherocytosis

    At 1 year following partial splenectomy, mean hemoglobin significantly increased by 3.0 1.4 g/dL (n 52), reticulocyte count decreased by 6.6% 6.6% (n 41), and bilirubin level[ncbi.nlm.nih.gov] Indications for laparoscopic removal of the spleen included anemia unresponsive to iron supplementation in eight patients (66.6 %) with increase need for red cells transfusions[ncbi.nlm.nih.gov] The hemoglobin levels increased by 1 g/dl, mean corpuscular hemoglobin concentration decreased by 1 g/dl, and the reticulocyte count decreased by 0.93%.[ori-japan.com]

  • Non-Hodgkin Lymphoma

    Tumor lysis syndrome is heralded by the development of hypocalcemia, hyperkalemia, hyperphosphatemia and hyperuricemia, as well as acute renal failure; consult nephrology[clinicaladvisor.com] Regarding our 3rd case, the laboratory findings revealed leukocytosis, anemia, thrombocytosis, increased inflammatory biomarkers, elevated LDH, and a low level of iron.[ncbi.nlm.nih.gov] One indicator of the potential for tumor lysis syndrome is an elevated plasma lactate dehydrogenase level or hyperuricemia at the time of diagnosis.[emedicine.medscape.com]

  • Chronic Kidney Insufficiency

    Because of increased iron utilization with stimulated erythropoiesis, iron stores must be replaced, often requiring parenteral iron.[merckmanuals.com] Iron therapy can help increase levels of iron in the body when EPO therapy alone is not effective. Vitamin D helps keep bones strong and healthy.[uwhealth.org] Contributing factors include anemia from reduced lifespan of the red blood cell, hemolysis and iron deficiency; falsely increased levels can occur from carbamylation of hemoglobin[clindiabetesendo.biomedcentral.com]

  • Thalassemia

    (NRBC) were significantly decreased, while the reticulocyte count significantly increased.[ncbi.nlm.nih.gov] Splenectomy is a risk factor for developing hyperuricemia and nephrolithiasis in patients with thalassemia intermedia:a retrospective study. Blood cells Mol Dis.[emedicine.medscape.com] The predominant mechanisms driving the process of iron loading include increased iron burden secondary to transfusion therapy in TDT and enhanced intestinal absorption secondary[ncbi.nlm.nih.gov]

  • Myelodysplasia

    Increased production and breakdown of blood cells can lead to hyperuricemia and hypermetabolism.[clevelandclinicmeded.com] Red blood cells contain iron, so if you have a lot of blood transfusions, the level of iron in your body will increase.[macmillan.org.uk] Patients with significant, refractory, or chronic anemia eventually develop iron overload due to transfusions and/or increased iron absorption from the gut.[merckmanuals.com]

  • Primary Myelofibrosis

    , and polychromatophilia and very elevated reticulocyte counts can occur. 263,264 The antiglobulin (Coombs) test usually is negative, but red cell autoantibodies can develop[patient-help.com] The mechanism of chronic hyperuricemia in our case might be rapid cell turnover due to ineffective erythropoiesis of PMF.[ncbi.nlm.nih.gov] […] for the increase in hemoglobin levels.[ncbi.nlm.nih.gov]

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