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98 Possible Causes for Hyperuricemia, Pruritus, Thrombocytosis

  • Diabetes Mellitus

    Fructose is also the only sugar able to increase blood uric acid concentrations, and SSB consumption has been linked to development of hyperuricemia (serum uric acid level[doi.org] […] outweighed by the benefits of reducing cardiovascular risk. [ 8 ] Presentation Patients with all types of diabetes may present with polyuria, polydipsia, lethargy, boils, pruritus[patient.info] Hypothesis: fructose-induced hyperuricemia as a causal mechanism for the epidemic of the metabolic syndrome. Nat Clin Pract Nephrol. 2005 ; 1 : 80–86.[doi.org]

  • Non-Hodgkin Lymphoma

    In the first case, the laboratory tests showed anemia, thrombocytosis, elevated inflammatory biomarkers, a low level of iron, and hypoproteinemia.[ncbi.nlm.nih.gov] Tumor lysis syndrome is heralded by the development of hypocalcemia, hyperkalemia, hyperphosphatemia and hyperuricemia, as well as acute renal failure; consult nephrology[clinicaladvisor.com] Common examples are follicular lymphoma and marginal zone lymphoma.Few subtypes of Non-Hodgkin lymphoma may also present with rash, pruritus, generalized aches and pains.[symptoma.com]

  • Myeloproliferative Disease

    One patient clearly represents a case of RARS with reactive thrombocytosis.[ncbi.nlm.nih.gov] […] leukemia and agnogenic myeloid metaplasia Easy bruising, bleeding, and/or symptoms of thrombosis Swollen, painful joint(s) secondary to gouty arthritis that is secondary to hyperuricemia[emedicine.com] Common symptoms include: headaches blurred vision fatigue weakness dizziness itchiness (pruritus) night sweats raised blood pressure (hypertension).[leukaemia.org.au]

  • Polycythemia Vera

    Objectives: To compare the mutational profiles of patients with primary myelofibrosis (PMF), polycythemia vera (PV), and essential thrombocytosis (ET).[ncbi.nlm.nih.gov] The maximum-tolerated dose of gandotinib was 120mg daily, based on dose-limiting toxicities of blood creatinine increase or hyperuricemia at higher doses.[ncbi.nlm.nih.gov] A detailed MEDLINE search for all English language articles related to PV, PV-associated pruritus and aquagenic pruritus that were published from 1965 till date was carried[ncbi.nlm.nih.gov]

  • Hodgkin's Disease

    She remained with a low level of pruritus until her death in July 2008, at the same dose of thalidomide.[ncbi.nlm.nih.gov] […] weeks primigravida was referred from the Emergency Department to the Medical Unit Khyber Teaching Hospital-MTI, Peshawar with four weeks of fever, progressive jaundice, pruritus[ncbi.nlm.nih.gov] Integumentary: Diffuse pruritus may appear because of lymph stasis. Head and Neck: Most patient may present with painless cervical lymphadenopathy.[symptoma.com]

  • Primary Myelofibrosis

    Objectives: To compare the mutational profiles of patients with primary myelofibrosis (PMF), polycythemia vera (PV), and essential thrombocytosis (ET).[ncbi.nlm.nih.gov] The mechanism of chronic hyperuricemia in our case might be rapid cell turnover due to ineffective erythropoiesis of PMF.[ncbi.nlm.nih.gov] KEYWORDS: JAK inhibitors; Primary myelofibrosis; Pruritus; Treatment options[ncbi.nlm.nih.gov]

  • Hereditary Spherocytosis

    It also results in leukocytosis and thrombocytosis. On peripheral blood smear, spherocytes are unchanged or may even increase.[medcaretips.com] A 18 year old Turkish patient with hereditary spherocytosis was admitted to hospital with pruritus and severe jaundice.[ncbi.nlm.nih.gov] […] develop and cholecystectomy may be associated with an increased risk of ca colon ) d) Visible jaundice but no stones for cosmetic reasons – difficult group Post op develop thrombocytosis[ihaematology.com]

  • Leukemia

    Myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis The criteria for MDS/MPN with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T; previously[doi.org] Hyperuricemia and a slightly raised lactate dehydrogenase (LDH) are common features.[web.archive.org] Thrombocytosis means that the blood platelet count is too high.[web.archive.org]

  • Chronic Myeloid Leukemia

    A 10-year-old boy presented with spontaneous bruising and was found to have extreme thrombocytosis without neutrophilia/shift to immaturity, basophilia or eosinophilia.[ncbi.nlm.nih.gov] Because of the increased turnover of myeloid cells, hyperuricemia may be present, and for this reason allopurinol is also indicated.[clinicaladvisor.com] Importantly, the accompanying pruritus can be severe enough to result in discontinuation of therapy.[ncbi.nlm.nih.gov]

  • Essential Thrombocythemia

    […] primary Thrombocytosis familial thrombocytosis hereditary thrombocythemia hemorrhagic thrombocythemia Primary Thrombocythemia essential thrombocytemia ET essential thrombocytosis[wikidata.org] The maximum-tolerated dose of gandotinib was 120mg daily, based on dose-limiting toxicities of blood creatinine increase or hyperuricemia at higher doses.[ncbi.nlm.nih.gov] […] respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly, thrombosis, bleeding, microcirculatory symptoms, pruritus[ncbi.nlm.nih.gov]

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