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20 Possible Causes for Hyperuricemia, Red Blood Cell Distribution Width Increased

  • Thalassemia

    blood cell distribution width High Normal; occasionally high Normal Ferritin Low Normal Normal Mentzer index for children (MCV/red blood cell count) 13 13 13 Hb electrophoresis[aafp.org] Splenectomy is a risk factor for developing hyperuricemia and nephrolithiasis in patients with thalassemia intermedia:a retrospective study. Blood cells Mol Dis.[emedicine.medscape.com] Occasionally, gout due to hyperuricemia, as well as kidney stones, are seen more frequently as patients with thalassemia major are living longer.[emedicine.medscape.com]

  • Myelodysplasia

    Increased production and breakdown of blood cells can lead to hyperuricemia and hypermetabolism.[clevelandclinicmeded.com] Hypermetabolism caused by increased blood cell turnover can lead to hyperuricemia, gout, stomach ulcers, weight loss, and kidney stones.[clevelandclinicmeded.com]

  • Sickle Cell Disease

    Delayed hemolytic transfusion reaction (DHTR) is a life-threatening complication in patients with sickle cell disease, characterized by difficulties in diagnosis and management. Certain reports have suggested successful salvage treatment with the terminal complement inhibitor, eculizumab. We here report evidence of[…][ncbi.nlm.nih.gov]

  • Hereditary Spherocytosis

    FBC shows raised MCHC and increased red cell distribution width.[patient.info] FBC and blood film including reticulocyte count. Spherocytes and reticulocytosis are seen on peripheral blood film.[patient.info] […] on the basis of a family history, typical clinical features and laboratory investigations - spherocytes, raised mean corpuscular haemoglobin concentration (MCHC), and an increase[patient.info]

  • Acute Myelocytic Leukemia

    The only significant difference in blood-cell indexes was an increase in red-cell distribution width (13.8% vs. 13.4% in normocytic subjects, P 0.002 by Wilcoxon rank-sum[doi.org] Hydration and allopurinol or rasburicase are used for treatment of hyperuricemia, hyperphosphatemia, hypocalcemia, and hyperkalemia (ie, tumor lysis syndrome ) caused by the[merckmanuals.com] […] weakness, pallor, and weight loss- Caused by increased leukocyte production which require increased nutrient production; destruction of cells also increases metabolic waste - Hyperuricemia[physio-pedia.com]

  • Pernicious Anemia

    […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org] […] decreased Average amount of hemoglobin in RBCs (mean corpuscular hemoglobin, MCH)—decreased Hemoglobin concentration (mean corpuscular hemoglobin concentration, MCHC)—decreased Increased[labtestsonline.org]

  • Autoimmune Hemolytic Anemia

    […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org] Wadsworth, Hyperuricemia and Reticulocytopenia in Association With Autoimmune Hemolytic Anemia in Two Children, American Journal of Clinical Pathology, 10.1309/8DXD-VJT9-UN60[oadoi.org] […] decreased Average amount of hemoglobin in RBCs (mean corpuscular hemoglobin, MCH)—decreased Hemoglobin concentration (mean corpuscular hemoglobin concentration, MCHC)—decreased Increased[labtestsonline.org]

  • Heart Failure

    blood cell distribution width II - Prognostic implications Many studies have shown anaemia to increase mortality and morbidity in HF patients ( 1, 5, 8, 9 ) and to cause[web.archive.org] Abstract Hyperuricemia is an independent predictor of mortality in patients with chronic heart failure.[ncbi.nlm.nih.gov] Yuzhi Zhen, Yanqiu Gao, Li Tian, Le Wang, Lishuang Ji, Gang Liu, Zhenguo Ji and Kunshen Liu , Prednisone in Uric Acid Lowering in Symptomatic Heart Failure Patients With Hyperuricemia[dx.doi.org]

  • Congestive Heart Failure

    blood cell distribution width II - Prognostic implications Many studies have shown anaemia to increase mortality and morbidity in HF patients ( 1, 5, 8, 9 ) and to cause[web.archive.org] Yuzhi Zhen, Yanqiu Gao, Li Tian, Le Wang, Lishuang Ji, Gang Liu, Zhenguo Ji and Kunshen Liu , Prednisone in Uric Acid Lowering in Symptomatic Heart Failure Patients With Hyperuricemia[doi.org] Yuzhi Zhen, Yanqiu Gao, Li Tian, Le Wang, Lishuang Ji, Gang Liu, Zhenguo Ji and Kunshen Liu, Prednisone in Uric Acid Lowering in Symptomatic Heart Failure Patients With Hyperuricemia[dx.doi.org]

  • Secondary Myelofibrosis

    Fecal occult blood test was positive. A peripheral blood smear revealed increased red cell distribution width with basophilic stippling.[bmccancer.biomedcentral.com] Complications gout : from hyperuricemia due to increased hematopoietic turnover splenic rupture (rare) 9 bleeding from thrombocytopenia (see case 8) General differential considerations[radiopaedia.org] Hyperuricemia and secondary gout may ensue.[theoncologyinstitute.com]

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