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Waldenstrom Macroglobulinemia
Hyperviscosity can precipitate heart failure that is exacerbated by concomitant anemia.[clinicaladvisor.com]
Of the immunoglobulin classes, IgM is most associated with hyperviscosity because of its pentamer structure.[hematology.org]
Hyperviscosity syndrome At least 50% of individuals with WM have hyperviscosity syndrome, an increased viscosity or thickening of the blood caused by the accumulation of IgM[medical-dictionary.thefreedictionary.com]
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Multiple Myeloma
Hyperviscosity: Emergent plasmapheresis B.[clinicaladvisor.com]
Generalized malaise, fever, sluggish mentation, paresthesia, sensory loss, and infection can indicate hyperviscosity.[symptoma.com]
Diuretic therapy should be avoided in patients with hyperviscosity.[cancertherapyadvisor.com]
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Heavy Chain Disease
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Systemic Lupus Erythematosus
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Dehydration
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Hyperviscosity Syndrome
There some early signs of Hyperviscosity, especially in senior population.[farlong.com]
Other conditions associated with blood hyperviscosity include shock, rheumatic disease, and diabetes.[symptoma.com]
[…] vary by pathology; including serum hyperviscosity, which may cause neurologic or ocular disorders; polycythemic hyperviscosity, which results in reduced blood flow or capillary[en.wikipedia.org]
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Asparaginase
Although plasma viscosity was not determined, this observation makes it very probable that the neurological symptoms were related to a hyperlipidemia-associated hyperviscosity[annonc.oxfordjournals.org]
In conclusion, our case report suggests that l -asparaginase-associated hypertriglyceridemia can occur in adult patients [ 1 ] and CNS symptoms may be caused by a hyperviscosity[annonc.oxfordjournals.org]
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Maternofetal Transfusion
Hyperviscosity in the neonate. J Pediatr 1973;82:1004. Hein HA and Lathrop SS.[uichildrens.org]
Because of the plethora and the likelihood of hypervolemia and hyperviscosity, the transfusion was continued until the equivalent of one blood volume of the infant (200 ml[journals.lww.com]
Infants with symptoms consistent with hyperviscosity should be tested immediately.[uichildrens.org]
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Ovarian Hyperstimulation Syndrome
The pathogenesis of thromboembolism in OHSS is not fully understood, though hemoconcentration and blood hyperviscosity seem to play a role in developing thrombotic changes[moh-it.pure.elsevier.com]
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Pancytopenia
For those with symptomatic hyperviscosity, one option is plasmapheresis because 80% of the IgM protein is intravascular.[healio.com]
Often, patients can have hyperviscosity, and the physical examination should include an assessment of this (eg, a retinal exam).[healio.com]
With rituximab monotherapy, the flare rate can be as high as 50%, resulting in symptomatic hyperviscosity and worsening of other IgM-related symptoms.[healio.com]