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1,419 Possible Causes for Hypochromatism, Microcytic Anemia, Plummer-Vinson Syndrome

  • Iron Deficiency Anemia

    The most used name is Plummer-Vinson syndrome, named after Henry Stanley Plummer (1874–1936) and Porter Paisley Vinson (1890–1959) who were physicians on the staff of the[] Abstract Iron-refractory iron deficiency anemia (IRIDA) is a rare autosomal recessive disease characterized by congenital hypochromic microcytic anemia, low transferrin saturation[] Patients have hypochromic microcytic anemia refractory to oral iron and are only partially responsive to parenteral iron administration.[]

  • Anemia of Chronic Disease

    Rare symptoms & signs: -Glossitis or angular cheilitis -Dysphagia due to esophageal web (Plummer-Vinson syndrome) -Koilonychia; "Spoon" fingernails -Pica -soreness of mouth[] Conclusions: CD should be included in the differential diagnosis of microcytic anemia.[] Iron deficiency anemia (IDA) and anemia of chronic disease (ACD) are the most prevalent, both characterized by hypochromic microcytic anemia and low serum iron (SI).[]

  • Iron Deficiency

    Symptoms of iron deficiency include: fatigue dizziness/lightheadedness pallor hair loss twitches irritability weakness pica brittle or grooved nails hair thinning PlummerVinson[] Differentiation from other microcytic anemias Iron deficiency anemia must be differentiated from other microcytic anemias (see table Differential Diagnosis of Microcytic Anemia[] This is the Paterson-Brown-Kelly syndrome (or Plummer-Vinson syndrome) and there is an association with oesophageal carcinoma.[]

    Missing: Hypochromatism
  • Plummer-Vinson Syndrome

    The authors report the case of a 6 year old with Plummer-Vinson syndrome.[] Blood tests demonstrate a hypochromic microcytic anemia that is consistent with an iron-deficiency anemia.[] Plummer-Vinson syndrome can be treated effectively with iron supplementation and mechanical dilation.[]

    Missing: Hypochromatism
  • Cooley's Anemia

    The defective gene in Cooley's anemia is on chromosome 11. The insufficient production of the globin chains results in microcytic anemia.[] Heterozygous gammabeta(0) mice suffer from microcytic anemia.[] The early papers by Cooley 2 described the condition as being characterized by a hypochromic microcytic anemia with many distorted erythrocytes which were usually resistant[]

    Missing: Plummer-Vinson Syndrome
  • Alpha-Thalassemia

    MATERIAL AND METHODS: Two hundred six patients with hypochromic microcytic anemia were evaluated for alpha thalassemia.[] Note : Thalassemia is a microcytic, hypochromic anemia. Its cause is a genetically based decreased synthesis of one or several globin chains.[] The proband, a 36 year-old male, presented with chronic borderline anemia and microcytic hypochromic parameters.[]

    Missing: Plummer-Vinson Syndrome
  • Lead Poisoning

    Anemia Leukocytosis Urine microscopy of sediment or renal biopsy Acid-fast inclusion bodies in tubular nuclei Pathognomonic for lead poisoning Free Erythrocyte Protoporphyrin[] Creates a microcytic anemia, with basophilic stippling Often seen concurrently with iron deficiency (GI transporters will more avidly uptake heavy metals in this situation[] All three patients had microcytic microchromic anemia with basophilic stippling of the erythrocytes, lead lines in X-ray of the knee joint and high blood lead levels.[]

    Missing: Plummer-Vinson Syndrome
  • Lead Poisoning in Children

    The blood dyscrasias manifested by often microcytic hypochromic anemia because often associated with iron deficiency, which explains the weakness in these children.[] Further exploration revealed hypochromic microcytic anemia (7.5g/dl; normal 11.0-14.5g/dl); a blood smear revealed the presence of basophilic inclusions in erythrocytes (Figure[] anemia as is the case of our patient with anemia of 7.5 g/dl.[]

    Missing: Plummer-Vinson Syndrome
  • Leukoerythroblastic Anemia

    : hematology, myeloid hematologic disease (primarily D50-D77, 280-289 ) RBCs / hemoglobinopathy Polycythemia - Macrocytosis - Anemia Nutritional Iron deficiency anemia ( Plummer-Vinson[] Differential Diagnosis Common Myeloproliferative Neoplasms - Overview CML PV PMF ET Tyrosine kinase ABL JAK2 JAK2 or MPL JAK2 or MPL Blood WBC with IG, basophils Normo or hypochromatic[] Nephropathy 2 hemolytic anemia hypochromic anemia Leukemoid Reaction macrocytic anemia Malarial Anemia microcytic anemia multiple myeloma myelodysplastic/myeloproliferative[]

  • Hookworm Infection

    Hookwork disease identification chonic parasitic infection iron deficiency and hypochromic, microcytic anemia, Children w/heavy long term infection may have hypoprteinemia[] Hookworm can cause hypothermia that is severe enough to reduce fever caused by malaria. 25 Other than hypochromic microcytic anemia, the most prominent laboratory finding[]

    Missing: Plummer-Vinson Syndrome

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