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1,107 Possible Causes for Hypoglycemia, Progressive Muscle Weakness

  • Adrenal Insufficiency

    Hypoglycemia occurred in three patients (10%) during the fasting day but not during the nonfasting day (P 0.23). Hypoglycemia was asymptomatic in two cases.[ncbi.nlm.nih.gov] Symptoms of Adrenal Insufficiency Progressive fatigue and muscle weakness Nausea and vomiting Decreased appetite and weight loss Increased pigmentation of skin and mucous[healthcommunities.com] Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone[fpnotebook.com]

  • Glycogen Storage Disease Type 2

    Although there are no reports in the literature of drugs precipitating hypoglycemia in children with GSD III, drugs known to cause hypoglycemia should be avoided.[nature.com] It is characterized by delayed motor skills (such as rolling over and sitting) and progressive muscle weakness.[ghr.nlm.nih.gov] Late-onset Pompe's disease is characterized by progressive muscle weakness and loss of respiratory function, leading to early death.[ncbi.nlm.nih.gov]

  • Glycogen Storage Disease Type 3

    Hypoglycemia stimulates epinephrine production which causes the breakdown of muscle glycogen forming lactate.[biologydiscussion.com] Hepatic disease and progressive muscle weakness are the major causes of long term morbidity.[symptoma.com] Progressive muscle weakness also occurs.[emedicine.medscape.com]

  • Endocrine Dysfunction

    Mutations in PTRH2 cause novel infantile-onset multisystem disease with intellectual disability, microcephaly, progressive ataxia, and muscle weakness . Ann. Clin.[nature.com] Complications of abnormal pituitary function, diabetes mellitus, hypoglycemia, pheochromocytoma, male hypogonadism, and androgen use are also covered.[oxfordmedicine.com] Due to the diversity of the musculoskeletal complications, it is beyond the scope of this discussion to include the disease progression of each disorder.[now.aapmr.org]

  • Dementia

    […] hydrocephalus, a buildup of fluid in the brain Metabolic disorders such as a vitamin B12 deficiency Low levels of thyroid hormones, called hypothyroidism Low blood sugar , called hypoglycemia[webmd.com] In vascular dementia, the first symptoms are often the neurological ones, such as problems with reflexes, walking, and muscle weakness.[verywellhealth.com] Mortality/Morbidity Some causes of delirium (eg, delirium tremens , severe hypoglycemia , CNS infection, heatstroke, thyroid storm ) may be fatal or result in severe morbidity[emedicine.medscape.com]

  • Glycogen Storage Disease Type 4

    The build-up of glycogen causes progressive muscle weakness ( myopathy ) throughout the body and affects various tissues, particularly the heart, skeletal muscles, liver,[snpedia.com] Meticulous adherence to a dietary regimen may reduce liver size, prevent hypoglycemia, reduce symptoms, and allow for growth and development.[emedicine.medscape.com] Infant-onset Type 2 GSD symptoms include: Muscle weakness and floppiness Delayed motor skills Weak breathing Progressive heart muscle enlargement and reduced pumping may lead[cancercarewny.com]

  • Glycogen Storage Disease Type 6

    Some cases experience no hypoglycemia at all.[symptoma.com] Infant-onset Type 2 GSD symptoms include: Muscle weakness and floppiness Delayed motor skills Weak breathing Progressive heart muscle enlargement and reduced pumping may lead[cancercarewny.com] Persons with late-onset type of GSD II usually have progressive muscle weakness and breathing problems, and shortened life spans.[geneaware.clinical.bcm.edu]

  • Glycogen Storage Disease Type 5

    Infant-onset Type 2 GSD symptoms include: Muscle weakness and floppiness Delayed motor skills Weak breathing Progressive heart muscle enlargement and reduced pumping may lead[cancercarewny.com] Symptoms vary from mild and easily controlled hypoglycemia to severe organ involvement that may lead to cardiac and respiratory failure.[checkorphan.org] Glycogen storage disease type II involves progressive muscle weakness in the trunk, lower limbs, and diaphragm.[path.upmc.edu]

  • Glycogen Storage Disease Type 1

    The main goal is to avoid hypoglycemia and maintain a normoglycemic state.[symptoma.com] The build-up of glycogen causes progressive muscle weakness ( myopathy ) throughout the body and affects various tissues, particularly the heart, skeletal muscles, liver,[snpedia.com] Infant-onset Type 2 GSD symptoms include: Muscle weakness and floppiness Delayed motor skills Weak breathing Progressive heart muscle enlargement and reduced pumping may lead[cancercarewny.com]

  • Phosphorylase Kinase Deficiency

    Since the majority of children with recurrent hypoglycemia cannot be diagnosed with a known endocrine or metabolic disorder on a critical sample, ketotic hypoglycemia has[doi.org] In some cases, patients may present with progressive muscle weakness. Symptoms are usually mild, and myopathy may be asymptomatic.[rarediseases.info.nih.gov] PhK deficiency , which is considerably rarer (characterized by any of the following: exercise intolerance, myalgia, muscle cramps, myoglobinuria, and progressive muscle weakness[ncbi.nlm.nih.gov]

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