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46 Possible Causes for Hypogranulosis

  • Diffuse Palmoplantar Keratoderma

    Histologic findings include orthokeratotic hyperkeratosis associated with hypergranulosis or hypogranulosis and moderate acanthosis.[]

  • Acquired Ichthyosis

    On light microscopy, all skin specimens displayed orthokeratotic hyperkeratosis and hypogranulosis. Three of them presented focal parakeratosis.[] Skin punch biopsies of ichthyosiform plaques showed compact lamellar orthohyperhkeratosis and hypogranulosis, which were consistent with familiar ichtyosis or acquired ichthyosis[]

  • Esophagitis Medicamentosa

    Examination of the biopsy specimen obtained from the knee revealed regular acanthosis and hypogranulosis, mild spongiosis , and intraepidermal clusters of neutrophils (Munro's[]

  • Epidermal Nevus Syndrome

    . - Characteristic histologic feature is regular alternation of slightly raised parakeratotic areas without a granular layer (hypogranulosis) and slightly depressed orthokeratotic[]

  • Hyperkeratosis Lenticularis Perstans

    Histologic Features A thick laminated overlying orthokeratosis Depressed, flattened epidermis with hypogranulosis Epidermal hyperplasia at the periphery of the lesion Moderate[] The epidermis is atrophic and shows hypogranulosis as well as a thinned spinous layer.[]

  • Lamellar Ichthyosis Type 2

    At light microscopic examination, a thick compact stratum corneum with parakeratosis, hypogranulosis and hyperkeratosis of the hair canals is seen ( 19 ).[]

  • Brandt Syndrome

    Confluent parakeratosis with associated hypogranulosis and dermal edema may be present. Subcorneal vesicle formation in the pale areas is also observed.[] […] keratinocytes within the superficial stratum spinosum and stratum granulosum of the epidermis is said to be almost pathognomonic. [1] Other features are confluent parakeratosis, hypogranulosis[]

  • Seborrheic Keratosis

    The areas of squamous cell carcinoma were characterized by areas of squamous dysplasia (100%), hypogranulosis (79.6%), squamous eddies (79.6%), solar elastosis (80.9%), and[]

  • Graft-versus-Host-Disease

    However, no typical histologic findings of psoriasis such as spongiform pustules of Kogoj, Munro's microabscesses, hypogranulosis, or rete ridge elongation were observed.[]

  • Lichen Simplex Chronicus

    In plaques of PN, microabscesses in the horny layer, hypogranulosis, regular acanthosis and thinning of the suprapapillary plates were more frequent, and hyperpigmentation[]

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