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100 Possible Causes for Hyponatremia, Ketonuria

  • Diabetic Ketotic Coma

    Hyponatremia needs to be corrected only when the sodium level is still low after adjusting for this effect.[] Because of a preferential increase in 3-OHBA, ketonuria seemed to be absent in the regular nitroprusside test.[] Often 50 mmol/L - no detectable ketonuria or acidosis - hypernatraemia (may be hypo-) - uraemia - /- respiratory alkalosis - increased osmolality Differential diagnosis -[]

  • Diabetes Mellitus

    In this T1D case with CKD, severe hyperglycemia in conjunction with other metabolic insults, such as uremia, hyponatremia, and hypocalcemia, probably provoked his seizure[] Although neither ketoacidosis nor ketonuria was detected, the markedly acute onset of the hyperglycemia was consistent with the typical clinical course of fulminant type I[] Comments Acetohexamide* 250 mg once/day–750 mg bid 12–24 h No longer available in US Chlorpropamide * 100 mg once/day–750 mg once/day 24–36 h Chlorpropamide : May cause hyponatremia[]

  • Heat Exhaustion

    Clinically significant hyponatremia often results from voluntary overhydration and can be dangerous. 20 Clinical manifestations of hyponatremia include nonspecific symptoms[] Hyponatremia in distance runners: Fluid and sodium balance during exercise. Curr Sports Med Rep . 2002;1:197–207. 22.[]

  • Third Trimester Pregnancy

    OBJECTIVES: A proper implantation of trophoblastic cells and an appropriate metalloproteinases activity is required to cause disintegration of basal membranes of cells. The activity of tissue matrix metaloproteinases can be inhibited by their matrix inhibitors - TIMP-s. Survivin is a member of inhibitor of apoptosis[…][]

  • Diabetic Ketoacidosis

    Halperin reports holding a patent on the use of sodium-linked glucose transporter 2 inhibitors to increase the excretion of water in patients with hyponatremia (US 8,518,895[] Abstract Diabetic ketoacidosis (DKA) is a complex metabolic state characterized by hyperglycemia, metabolic acidosis and ketonuria.[] High serum osmolarity also drives water from intracellular to extracellular space, causing dilutional hyponatremia.[]

  • Vomiting of Pregnancy

    PARTICIPANTS: Women less than 20 weeks' pregnant with severe NVP and associated ketonuria ( 1 ).[] Antiemetic agent selected did not differ by patient age, parity, current treatment for nausea and vomiting in pregnancy, orthostatics, ketonuria or disposition.[] Hyperemesis gravidarum refers to persistent and severe vomiting leading to fluid and electrolyte disturbance, marked ketonuria, nutritional deficiency and weight loss.[]

  • Hyperglycemia

    Large-scale absorption of irrigating fluid (3 L) induced dilutional hyponatremia (120 mmol/L) and hyperglycemia (30 mmol/L).[] The urine analysis had evidence of glycosuria and ketonuria.[] Abstract A 15-year-old female presented to a pediatric emergency department with glycosuria, ketonuria, and hyperglycemia and was admitted with a presumed diagnosis of diabetes[]

  • Hyperosmolar Hyperglycemic Nonketotic Coma

    This can cause neurological effects, and also can induce a hyperosmotic hyponatremia (because serum sodium will be diluted).[] Measurement of ketone bodies , to DDx from DKA, which are the underlying driver for DKA, but are usually NOT detectable in HONK, including: Small ketones on dipstick Absent-to-low ketonuria[] Hyperglycemia-induced hyponatremia - calculation of expected serum sodium depletion (letter).[]

  • Hyperproteinemia

    In multivariate analysis, hyperproteinemia at the 6-hr time point predicted hyponatremia (P 0.000), and hyperproteinemia at the 24-hr time point predicted both hyponatremia[] In untreated diabetes mellitus , hyperglycemia is often associated with ketoacidosis, which can result in glycosuria and ketonuria (loss of glucose and ketones with urine)[] It can result in a falsely low appearing sodium level (hyponatremia).[]

  • Anterior Pituitary Hypofunction

    […] increased plasma osmolality What is syndrome of inappropriate ADH secretion what is the effect of SIADH too much ADH thus concentrated urine, dcreased plasma osmolality and hyponatremia[] The vomiting is intractable, occur irrespective of food and severe enough to require hospitalization. 2 It is complicated by weight loss, dehydration, ketonuria sometimes[] Hyponatremia Low serum osmolality Mental status changes what is the diagnostic criteria for SIADH?[]

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