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25 Possible Causes for Hyponatremia, Lower Extremity Cellulitis

  • Congestive Heart Failure

    A variety of conditions result in lower extremity edema, such as deep vein thrombosis, cellulitis, venous stasis insufficiency, and congestive heart failure (CHF).[] We describe the use of conivaptan in a 4-month-old infant girl with severe hypervolemic hyponatremia and heart failure.[] It seems that icodextrin may contribute to clinically relevant hyponatremia if the hyponatremia is compounded by other factors.[]

  • Diabetes Mellitus

    In this T1D case with CKD, severe hyperglycemia in conjunction with other metabolic insults, such as uremia, hyponatremia, and hypocalcemia, probably provoked his seizure[]

  • Chronic Right-Sided Congestive Heart Failure

    Specifically, tolvaptan is approved by the FDA for the treatment of euvolemic hyponatremia and hypervolemic hyponatremia.[] Monitor for hyponatremia. For pulmonary edema, an extreme of CHF, morphine and IV nitrates are adjuncts.[] References: [4] [8] [2] [19] [9] [20] [21] Treatment General measures Lifestyle modifications Salt restriction ( 3 g/day) Fluid restriction in patients with edema and/or hyponatremia[]

  • Secondary Lymphedema

    Thus, we clinically applied the technique of lymphatic vessel-to-isolated-saphenous-vein anastomosis in a patient with secondary lymphedema of the bilateral lower extremities[] This provoked unstable, fluctuating blood pressures, hyperglycemia and hyponatremia, which affected the patient's hemodynamic status.[] A significant reduction of morbidity was also seen following liposuctioning for secondary lower extremity lymphedema: frequency of episodes of cellulitis was reduced as were[]

  • Hypogammaglobulinemia

    He had experienced multiple episodes of lower extremity cellulitis, left more frequent than right leg, beginning in childhood.[] Laboratory examinations revealed hyponatremia, hyperkalemia, hypoproteinemia, hypogammaglobulinemia, elevated plasma renin activity and hyperaldosteronemia.[]

  • Moxifloxacin

    "Moxifloxacin-associated neutropenia in a cirrhotic elderly woman with lower extremity cellulitis (April)." Ann Pharmacother 42 (2008): 580-3 8.[] Clinicians should be aware of this potential adverse drug effect when assessing patients with hyponatremia or SIADH.[] A 66-year-old woman developed severe hyponatremia after receiving moxifloxacin for five days for treatment of COPD exacerbation.[]

  • Disseminated Cryptococcosis

    A 34-year-old man developed severe cellulitis on his both lower extremities without any preceding injury and allergies.[] Here, we describe the case of a 46-year-old healthy man who presented with primary adrenal insufficiency with hyponatremia, hyperkalemia and skin pigmentation.[] We reported the first case of patients with nephrotic syndrome suffering from disseminated cryptococcosis initially presented as cellulitis.[]

  • Burn Injury

    The authors describe split-thickness skin grafting in one patient with X-linked ichthyosis who sustained a burn with crush injury to his bilateral lower extremities.[] Cerebral edema and seizures can occur with severe hyponatremia, and rapid correction of hyponatremia may result in central pontine demyelinating lesions.[] Although he developed cellulitis, there is no evidence that patients with ichthyosis have higher rates of infection.[]

  • Legionella Pneumophila

    […] of the lower extremity, which responded to an extended course of levofloxacin.[] Clinical manifestations are nonspecific, but high fever, diarrhea, and hyponatremia are often distinctive.[] […] would alter empirical decisions (Infectious Diseases Society of America [IDSA] and American Thoracic Society [ATS], 2007) Nonspecific testing – may reveal Serum sodium – hyponatremia[]

  • Morphine

    On admission, her blood pressure was 185/65 mm Hg, and clonus was noted in the lower extremities.[] The patient was hospitalized 10 days earlier for cellulitis of the left breast secondary to a left mastectomy 5 months earlier, and a short course of oral morphine was prescribed[]

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