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372 Possible Causes for Hyponatremia, Peripheral Motor Neuropathy

  • Acute Intermittent Porphyria

    motor neuropathy.[bestpractice.bmj.com] Neurovisceral symptoms resolved, and severe hyponatremia was corrected with IV saline solution without complications.[ncbi.nlm.nih.gov] A 45-year-old man with end-stage renal disease due to polycystic kidney disease was admitted to the hospital because of recurrent abdominal pain, progressive peripheral motor[ncbi.nlm.nih.gov]

  • Acute Hepatic Porphyria

    neuropathy (patchy numbness and paresthesias), Proximal motor weakness (usually starting in upper extremities which can progress to include respiratory impairment and death[house.wikia.com] Hyponatremia-associated rhabdomyolysis. Nephron. 1999;82(3):274-7. [8] 6- Rizzieri DA. Rhabdomyolysis after correction of hyponatremia due to psychogenic polydipsia.[revistanefrologia.com] Another important early sign of this disorder is hyponatremia.[hematologyandoncology.net]

  • Variegate Porphyria

    Respiratory paralysis 9-20 Preceded by progressive peripheral motor neuropathy and paresis.[clinicaladvisor.com] […] brainstem dysfunction in VP patients with a history of porphyric crises may be due to neurotoxic effects of porphyrin precursors as well as subclinical osmolarity changes due to hyponatremia[ncbi.nlm.nih.gov] The most common symptoms are abdominal pain; constipation; pain in the back, chest and extremities; anxiety; seizures; and a predominantly motor peripheral neuropathy resulting[ncbi.nlm.nih.gov]

  • Mercury Poisoning

    A male subject, after exposure to mercury metal at work in 1968, developed classical signs of mercurialism from which he made a slow clinical recovery. He subsequently developed psychoneurotic symptoms and became an alcoholic; he never returned to work and died in 1984. No histological changes relevant to mercury[…][ncbi.nlm.nih.gov]

  • West Nile Encephalitis

    Routine labs to ensure resolution or stability of any notable blood abnormalities (e.g. sodium level in cases associated with hyponatremia). 3.[clinicaladvisor.com] Laboratory evaluation was significant only for mild hyponatremia (132 mmol/L) and elevated creatinine kinase (236 mmol/L).[hindawi.com] […] counts on admission usually show no major abnormalities, although there may be absolute or relative lymphopenia. 10,21 Up to one third of the patients develop significant hyponatremia[clevelandclinicmeded.com]

  • Diabetes Mellitus

    In this T1D case with CKD, severe hyperglycemia in conjunction with other metabolic insults, such as uremia, hyponatremia, and hypocalcemia, probably provoked his seizure[ncbi.nlm.nih.gov] Motor neuropathy and cranial mononeuropathy result from vascular disease in blood vessels supplying nerves.[emedicine.medscape.com] Comments Acetohexamide* 250 mg once/day–750 mg bid 12–24 h No longer available in US Chlorpropamide * 100 mg once/day–750 mg once/day 24–36 h Chlorpropamide : May cause hyponatremia[msdmanuals.com]

  • Chronic Kidney Insufficiency

    […] sensory and motor neuropathies, muscle cramps, hyperreflexia, restless legs syndrome, and seizures (usually the result of hypertensive or metabolic encephalopathy).[merckmanuals.com] Hypocalcemia (see chapter) Hyponatremia (see chapter) Uremia: The three most severe forms of uremia are encephalopathy, bleeding diathesis, and pericarditis.[clinicaladvisor.com] […] more severe renal disease (eg, estimated glomerular filtration rate [eGFR] 15 mL/min/1.73 m 2 ), neuromuscular symptoms may be present, including coarse muscular twitches, peripheral[merckmanuals.com]

  • Acute Renal Failure

    Treatment of hyponatremia is generally free-water restriction. In patients with severe AKI and more profound hyponatremia, renal replacement therapy may be necessary.[renalandurologynews.com] . -- Amyotrophic lateral sclerosis and other motor neuron diseases / Pamela J. Shaw -- Peripheral neuropathies / Michael E.[worldcat.org] Water intake can be further restricted for hyponatremia or increased for hypernatremia.[merckmanuals.com]

  • Porphyria

    Acute attacks occur mainly in adults and comprise severe abdominal pain, nausea, vomiting, autonomic disturbance, central nervous system involvement and peripheral motor neuropathy[ncbi.nlm.nih.gov] Computed tomography was unremarkable, and blood tests demonstrated hyponatremia, acute kidney injury, and a neutrophilic leukocytosis.[ncbi.nlm.nih.gov] Respiratory paralysis 9-20 Preceded by progressive peripheral motor neuropathy and paresis.[clinicaladvisor.com]

  • Hereditary Coproporphyria

    Peripheral neuropathies are predominantly motor neuropathies and can mimic Guillain-Barré syndrome.[emedicine.medscape.com] Serum sodium concentration should be checked in patients during attacks, since hyponatremia a quite common symptom.[symptoma.com] neuropathy (patchy numbness and paresthesias), Proximal motor weakness (usually starting in upper extremities which can progress to include respiratory impairment and death[house.wikia.com]

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