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382 Possible Causes for Hypopigmented Macule

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  • Tinea Versicolor

    Presented in this report is a 34-year-old man with an interesting case of folliculocentric tinea versicolor manifesting as perifollicular hypopigmented macules on the lower[ncbi.nlm.nih.gov] Clinically, it presents with a spectrum of findings that may include hypopigmented macules, erythematous plaques and nodules, and thickened or tender peripheral nerves.[ncbi.nlm.nih.gov] It manifests clinically as asymptomatic hypopigmented macules, hyperpigmented macules, or a combination of the two.[ncbi.nlm.nih.gov]

  • Vitiligo

    Vitiligo is signified by acquired white or hypopigmented macules or patches.[symptoma.com]

  • Pityriasis Alba

    Pityriasis alba (PA) is a relatively common skin disorder usually seen in children and young adults characterized by the presence of superficial hypopigmented macules.[ncbi.nlm.nih.gov] Clinical Features: Hypopigmented macules on the face of children, which is much more noticeable in dark-skinned individuals May be a variant of seborrheic dermatitis or atopic[dermpedia.org] The advantage is that they don’t cause cutaneous atrophy. [2] Photos Hypopigmented macules on the trunk Hypopigmented macules in a patient with eczema Literature 1.0 1.1 In[africanskindiseases.org]

  • Tuberous Sclerosis

    Hypopigmented macules are the earliest sign.[ncbi.nlm.nih.gov] The mother and other family members with the mutation were asymptomatic except for the presence of hypopigmented macules.[ncbi.nlm.nih.gov] Clinical examination showed distinctive dermatological signs like hypopigmented macules, shagreen plaques, miliary fibromas, fibrous plaques and multiple angiofibromas.[ncbi.nlm.nih.gov]

  • Dyskeratosis Congenita

    The hypopigmented macules showed no discernible erythema upon rubbing or the local application of heat.[ncbi.nlm.nih.gov] Cutaneous findings : The primary finding is abnormal skin pigmentation, with tan-to-gray hyperpigmented or hypopigmented macules and patches in a mottled or reticulated pattern[en.wikipedia.org] […] confirmed by detection of a 214 C T mutation in the DKC1 gene, and provide a detailed description of mottled pigmentary changes of the skin, specifically numerous small, whitish macules[ncbi.nlm.nih.gov]

  • T-Cell Lymphoma

    Early CTCL often lacks the histologic criteria necessary for a definitive diagnosis. 5 PVA presents as atrophic, hypopigmented and hyperpigmented macules and patches with[aafp.org] In dark-skinned individuals, the patches may appear as hypopigmented or hyperpigmented areas. As patches become more infiltrative, they evolve into palpable plaques.[patient.info] The skin disease generally progresses from: Patch phase (up to 15 cm across) : flat, erythematous pink-brown macules that may have a fine scale, may be single or multiple[patient.info]

  • Cutaneous T-Cell Lymphoma

    Early CTCL often lacks the histologic criteria necessary for a definitive diagnosis. 5 PVA presents as atrophic, hypopigmented and hyperpigmented macules and patches with[aafp.org] In dark-skinned individuals, the patches may appear as hypopigmented or hyperpigmented areas. As patches become more infiltrative, they evolve into palpable plaques.[patient.info] The skin disease generally progresses from: Patch phase (up to 15 cm across) : flat, erythematous pink-brown macules that may have a fine scale, may be single or multiple[patient.info]

  • Dyschromatosis Universalis Hereditaria 1

    Wu and Lin reported that hyperpigmented macule had lesser degree of acanthosis compared to the hypopigmented macule [ 3 ].[omicsonline.org] macules which form a reticulate or mottled pattern.[precedings.nature.com] Dyschromatosis universalis hereditaria is a rare genodermatosis characterized by hyper- and hypopigmented macules in a reticulate pattern.[scinapse.io]

  • Cystic Lung Disease

    Patients with TSC usually present angiomyolipomas, angiofibromas, hypopigmented macules, shagreen patch, and/or periungual fibromas.[archbronconeumol.org]

  • Acquired Disorder

    Oval (ash leaf) hypopigmented macules are the earliest cutaneous sign of tuberous sclerosis.[clevelandclinicmeded.com] Ash Leaf Spots Oval (ash leaf) hypopigmented macules are the earliest cutaneous sign of tuberous sclerosis.[clevelandclinicmeded.com]

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